Search Results - "Edelman, Lucas B."

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements by Schoenfelder, Stefan, Furlan-Magaril, Mayra, Mifsud, Borbala, Tavares-Cadete, Filipe, Sugar, Robert, Javierre, Biola-Maria, Nagano, Takashi, Katsman, Yulia, Sakthidevi, Moorthy, Wingett, Steven W, Dimitrova, Emilia, Dimond, Andrew, Edelman, Lucas B, Elderkin, Sarah, Tabbada, Kristina, Darbo, Elodie, Andrews, Simon, Herman, Bram, Higgs, Andy, LeProust, Emily, Osborne, Cameron S, Mitchell, Jennifer A, Luscombe, Nicholas M, Fraser, Peter

“…The mammalian genome harbors up to one million regulatory elements often located at great distances from their target genes. Long-range elements control genes…”
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Two-transcript gene expression classifiers in the diagnosis and prognosis of human diseases by Edelman, Lucas B, Toia, Giuseppe, Geman, Donald, Zhang, Wei, Price, Nathan D

“…Identification of molecular classifiers from genome-wide gene expression analysis is an important practice for the investigation of biological systems in the…”
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In silico models of cancer by Edelman, Lucas B., Eddy, James A., Price, Nathan D.

“…Cancer is a complex disease that involves multiple types of biological interactions across diverse physical, temporal, and biological scales. This complexity…”
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Lipid Infusion Accelerates Removal of Bupivacaine and Recovery From Bupivacaine Toxicity in the Isolated Rat Heart by Weinberg, Guy L., Ripper, Richard, Murphy, Patricia, Edelman, Lucas B., Hoffman, William, Strichartz, Gary, Feinstein, Douglas L.

“…Infusion of a lipid emulsion has been advocated for treatment of severe bupivacaine cardiac toxicity. The mechanism of lipid rescue is unknown. These studies…”
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Systems biology of embryogenesis by Edelman, Lucas B, Chandrasekaran, Sriram, Price, Nathan D

“…The development of a complete organism from a single cell involves extraordinarily complex orchestration of biological processes that vary intricately across…”
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Metabolic context affects hemodynamic response to bupivacaine in the isolated rat heart by Edelman, Lucas B., Ripper, Richard, Kelly, Kemba, Di Gregorio, Guido, Weinberg, Guy L.

“…Previous studies have demonstrated that the local anesthetic bupivacaine selectively inhibits oxidative metabolism of fatty acids in isolated cardiac…”
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Lipid Infusion Accelerates Removal of Bupivacaine and Recovery From Bupivacaine Toxicity in the Isolated Rat Heart by Weinberg, Guy L., Ripper, Richard, Murphy, Patricia, Edelman, Lucas B., Hoffman, William, Strichartz, Gary, Feinstein, Douglas L.

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Chapter 11 - Systems Biology and Systems Medicine by Price, Nathan D., Edelman, Lucas B., Lee, Inyoul, Yoo, Hyuntae, Hwang, Daehee, Carlson, George, Galas, David J., Heath, James R., Hood, Leroy

“…A systems approach to medicine argues that disease arises from disease-perturbed biological networks and the dynamically changing, altered patterns of gene…”
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CHAPTER 6 - Systems Biology and the Emergence of Systems Medicine by Price, Nathan D., Edelman, Lucas B., Lee, Inyoul, Yoo, Hyuntae, Hwang, Daehee, Carlson, George, Galas, David J., Heath, James R., Hood, Leroy

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