Search Results - "Edelman, L."

Machine learning approaches for integrating clinical and imaging features in late-life depression classification and response prediction by Patel, Meenal J., Andreescu, Carmen, Price, Julie C., Edelman, Kathryn L., Reynolds III, Charles F., Aizenstein, Howard J.

“…Objective Currently, depression diagnosis relies primarily on behavioral symptoms and signs, and treatment is guided by trial and error instead of evaluating…”
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Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease by Redente, Elizabeth F, Aguilar, Martin A, Black, Bart P, Edelman, Benjamin L, Bahadur, Ali N, Humphries, Stephen M, Lynch, David A, Wollin, Lutz, Riches, David W H

“…Rheumatoid arthritis (RA)-associated interstitial lung disease (RA-ILD) develops in ~20% of patients with RA. SKG mice, which are genetically prone to…”
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Transitional human alveolar type II epithelial cells suppress extracellular matrix and growth factor gene expression in lung fibroblasts by Correll, Kelly A, Edeen, Karen E, Zemans, Rachel L, Redente, Elizabeth F, Serban, Karina A, Curran-Everett, Douglas, Edelman, Benjamin L, Mikels-Vigdal, Amanda, Mason, Robert J

“…Epithelial-fibroblast interactions are thought to be very important in the adult lung in response to injury, but the specifics of these interactions are not…”
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Corticosteroids inhibit VEGF-induced vascular leakage in a rabbit model of blood–retinal and blood–aqueous barrier breakdown by Edelman, Jeffrey L., Lutz, David, Castro, Marisol R.

“…Recent clinical studies show that a single intravitreal injection of the corticosteroid triamcinolone acetonide (TAA) may reduce edematous retinal swelling and…”
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Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis by Redente, Elizabeth F, Chakraborty, Sangeeta, Sajuthi, Satria, Black, Bart P, Edelman, Ben L, Seibold, Max A, Riches, David Wh

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic disease of the distal lung alveoli that culminates in respiratory failure and…”
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Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis by Cooley, Joseph C, Javkhlan, Nomin, Wilson, Jasmine A, Foster, Daniel G, Edelman, Benjamin L, Ortiz, Luis A, Schwartz, David A, Riches, David Wh, Redente, Elizabeth F

“…Patients with progressive fibrosing interstitial lung diseases (PF-ILDs) carry a poor prognosis and have limited therapeutic options. A hallmark feature is…”
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Applying the Age-Friendly Health System Framework to Long Term Care Settings by Edelman, L. S., Drost, J., Moone, R. P., Owens, K., Towsley, G. L., Tucker-Roghi, G., Morley, John E.

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Lipid Infusion Accelerates Removal of Bupivacaine and Recovery From Bupivacaine Toxicity in the Isolated Rat Heart by Weinberg, Guy L., Ripper, Richard, Murphy, Patricia, Edelman, Lucas B., Hoffman, William, Strichartz, Gary, Feinstein, Douglas L.

“…Infusion of a lipid emulsion has been advocated for treatment of severe bupivacaine cardiac toxicity. The mechanism of lipid rescue is unknown. These studies…”
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Intravitreal Steroids for Macular Edema: The Past, the Present, and the Future by Cunningham, Matthew A., BS, Edelman, Jeffrey L., PhD, Kaushal, Shalesh, MD, PhD

“…Abstract Macular edema, a condition usually associated with an underlying disease process, is a common cause of severe visual loss. There have been a variety…”
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Trauma and resilience informed research principles and practice: A framework to improve the inclusion and experience of disadvantaged populations in health and social care research by Edelman, Natalie L

“…Trauma, socio-economic, cultural and structural issues are associated with poor outcomes for most health conditions and may also make research participation…”
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449 Progression of silica-induced pulmonary fibrosis is arrested after selective ablation of Col1a1+ fibroblasts by Foster, Daniel G, Javkhlan, Nomin, Wilson, Jasmine, Edelman, Benjamin L., Riches, David W. H., Redente, Elizabeth F.

“…OBJECTIVES/GOALS: Silicosis is a highly fatal progressive fibrotic disease of the lungs characterized by accumulation and persistence of fibroblasts that…”
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Increased cell surface Fas expression is necessary and sufficient to sensitize lung fibroblasts to Fas ligation-induced apoptosis: implications for fibroblast accumulation in idiopathic pulmonary fibrosis by Wynes, Murry W, Edelman, Benjamin L, Kostyk, Amanda G, Edwards, Michael G, Coldren, Christopher, Groshong, Steve D, Cosgrove, Gregory P, Redente, Elizabeth F, Bamberg, Alison, Brown, Kevin K, Reisdorph, Nichole, Keith, Rebecca C, Frankel, Stephen K, Riches, David W H

“…Idiopathic pulmonary fibrosis (IPF) is associated with the accumulation of collagen-secreting fibroblasts and myofibroblasts in the lung parenchyma. Many…”
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Retinal gene expression and visually evoked behavior in diabetic long evans rats by Kirwin, Stefanie J, Kanaly, Suzanne T, Hansen, Candice R, Cairns, Belinda J, Ren, Meina, Edelman, Jeffrey L

“…Patients with diabetic retinopathy may experience severe vision loss due to macular edema and neovascularization secondary to vascular abnormalities. However,…”
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[ 18 F]FDG, [ 11 C]PiB, and [ 18 F]AV-1451 PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline by Okonkwo, David O, Puffer, Ross C, Minhas, Davneet S, Beers, Sue R, Edelman, Kathryn L, Sharpless, Jane, Laymon, Charles M, Lopresti, Brian J, Benso, Steven, Puccio, Ava M, Pathak, Sudhir, Ikonomovic, Milos D, Mettenburg, Joseph M, Schneider, Walter, Mathis, Chester A, Mountz, James M

“…Trauma-related neurodegeneration can be difficult to differentiate from multifactorial neurodegenerative syndromes, both clinically and radiographically. We…”
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Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells by Nehmé, Alissar, Lobenhofer, Edward K, Stamer, W Daniel, Edelman, Jeffrey L

“…In addition to their well-documented ocular therapeutic effects, glucocorticoids (GCs) can cause sight-threatening side-effects including ocular hypertension…”
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Quantitative Image Analysis of Laser-induced Choroidal Neovascularization in Rat by Edelman, Jeffrey L, Castro, Marisol R

“…Rodent models of laser-induced choroidal neovascularization (CNV) are now extensively used to identify angiogenic proteins, determine the role of specific…”
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Efficient Transduction of Neural Cells In Vitro and In Vivo by a Baculovirus-Derived Vector by Sarkis, C, Serguera, C, Petres, S, Buchet, D, Ridet, J L, Edelman, L, Mallet, J

“…Gene delivery to the central nervous system is central to the development of gene therapy for neurological diseases. We developed a baculovirus-derived vector,…”
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New Persistent Opioid Use Among Patients With Cancer After Curative-Intent Surgery by Lee, Jay Soong-Jin, Hu, Hsou Mei, Edelman, Anthony L, Brummett, Chad M, Englesbe, Michael J, Waljee, Jennifer F, Smerage, Jeffrey B, Griggs, Jennifer J, Nathan, Hari, Jeruss, Jacqueline S, Dossett, Lesly A

“…Purpose The current epidemic of prescription opioid misuse has increased scrutiny of postoperative opioid prescribing. Some 6% to 8% of opioid-naïve patients…”
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Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing by Edelman, Theresa L B, McCulloch, Katherine A, Barr, Angela, Frøkjær-Jensen, Christian, Jorgensen, Erik M, Rougvie, Ann E

“…The Caenorhabditis elegans heterochronic gene pathway regulates the relative timing of events during postembryonic development. lin-42, the worm homolog of the…”
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Myeloid sarcoma of the periprostatic tissue and prostate: Case report and review of literature by Koppisetty, Shalini, Edelman, Brain, Rajpurkar, Atul

“…Myeloid sarcoma (MS) is a rare extramedullary tumor composed of immature cells of myeloid lineage that destroy the original tissue architecture in which it is…”
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