Search Results - "Edelman, Kathryn"

Machine learning approaches for integrating clinical and imaging features in late-life depression classification and response prediction by Patel, Meenal J., Andreescu, Carmen, Price, Julie C., Edelman, Kathryn L., Reynolds III, Charles F., Aizenstein, Howard J.

“…Objective Currently, depression diagnosis relies primarily on behavioral symptoms and signs, and treatment is guided by trial and error instead of evaluating…”
Get full text

fMRI Correlates of White Matter Hyperintensities in Late-Life Depression by Aizenstein, Howard J., Andreescu, Carmen, Edelman, Kathryn L., Cochran, Jennifer L., Price, Julie, Butters, Meryl A., Karp, Jordan, Patel, Meenal, Reynolds, Charles F.

“…Brain activation differences during emotional processing between elderly patients with and without major depressive disorder were greater for depressed…”
Get full text

Amyloid-Beta Deposition is Associated with Increased Medial Temporal Lobe Activation during Memory Encoding in the Cognitively Normal Elderly by Edelman, Kathryn, M.S, Tudorascu, Dana, Ph.D, Agudelo, Christian, M.D, Snitz, Beth, Ph.D, Karim, Helmet, B.Sc, Cohen, Ann, Ph.D, Mathis, Chester, Ph.D, Price, Julie, Ph.D, Weissfeld, Lisa, Ph.D, Klunk, William, M.D., Ph.D, Aizenstein, Howard, M.D., Ph.D

“…Background Much is unknown about changes that occur in the brain in the years preceding the cognitive and functional impairment associated with Alzheimer…”
Get full text

[ 18 F]FDG, [ 11 C]PiB, and [ 18 F]AV-1451 PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline by Okonkwo, David O, Puffer, Ross C, Minhas, Davneet S, Beers, Sue R, Edelman, Kathryn L, Sharpless, Jane, Laymon, Charles M, Lopresti, Brian J, Benso, Steven, Puccio, Ava M, Pathak, Sudhir, Ikonomovic, Milos D, Mettenburg, Joseph M, Schneider, Walter, Mathis, Chester A, Mountz, James M

“…Trauma-related neurodegeneration can be difficult to differentiate from multifactorial neurodegenerative syndromes, both clinically and radiographically. We…”
Get full text

White Matter Hyperintensity Burden and Disability in Older Adults: Is Chronic Pain a Contributor? by Buckalew, Neilly, MS, MD, Haut, Marc W., PhD, Aizenstein, Howard, MD, PhD, Rosano, Caterina, MD, MPH, Edelman, Kathryn Dunfee, BS, Perera, Subashan, PhD, Marrow, Lisa, PhD, Tadic, Stasa, MD, Venkatraman, Vijay, MS, PhD, Weiner, Debra, MD

“…Objective To primarily explore differences in global and regional white matter hyperintensities (WMH) in older adults with self-reported disabling and…”
Get full text

White Matter Hyperintensity Accumulation During Treatment of Late-Life Depression by Khalaf, Alexander, Edelman, Kathryn, Tudorascu, Dana, Andreescu, Carmen, Reynolds, Charles F, Aizenstein, Howard

“…White matter hyperintensities (WMHs) have been shown to be associated with the development of late-life depression (LLD) and eventual treatment outcomes. This…”
Get full text

Preliminary Evidence for Improvement in Symptoms, Cognitive, Vestibular, and Oculomotor Outcomes Following Targeted Intervention with Chronic mTBI Patients by Kontos, Anthony P, Collins, Michael W, Holland, Cyndi L, Reeves, Valerie L, Edelman, Kathryn, Benso, Steven, Schneider, Walter, Okonkwo, David

“…Abstract Introduction To determine if targeted, active interventions would improve symptoms and impairment in previously intractable patients with chronic mild…”
Get full text

The correlation of in vivo tau with amyloid beta, hypometabolism, and cortical atrophy in chronic TBI subjects by Minhas, Davneet, Laymon, Charles, Beers, Sue, Sharpless, Jane, Puccio, Ava, Edelman, Kathryn, Mathis, Chester, Okonkwo, David, Mountz, James

“…Introduction: Traumatic brain injury (TBI) is associated with an earlier age of onset of Alzheimer's disease (AD). Recent neuropathologic studies characterize…”
Get full text

PET Imaging of Neurodegeneration With [18F]AV-1451 PET After Repetitive Traumatic Brain Injury by Mesley, Matthew, Puffer, Ross, Laymon, Charles, Lopresti, Brian, Edelman, Kathryn, Sharpless, Jane, Billigen, Julia, Wilkins, Tiffany, Puccio, Ava, Mathis, Chet, Mountz, James, Okonkwo, David O

Get full text

Altered cerebral blood flow patterns associated with pathologic worry in the elderly by Andreescu, Carmen, Gross, James J., Lenze, Eric, Edelman, Kathryn Dunfee, Snyder, Sara, Tanase, Costin, Aizenstein, Howard

“…Background: Generalized anxiety disorder (GAD) is the most prevalent anxiety disorder among the elderly and has high functional and cognitive morbidity…”
Get full text

Comparison of [18F]AV-1451 PET with HDFT in chronic TBI subjects by Mountz, James, Minhas, Davneet, Laymon, Charles, Beers, Sue, Puccio, Ava, Edelman, Kathryn, Sharpless, Jane, Lopresti, Brian, Puffer, Ross, Schneider, Walter, Mathis, Chester, Okonkwo, David

“…Objectives: Traumatic brain injury (TBI) subjects are more likely to have dementia characterized by increased hyperphosphorylated tau at an early age, relative…”
Get full text

Targeted Intervention Improves Symptoms and Impairments in Patients With Mild Traumatic Brain Injury With Chronic Symptom: A Prospective, Multiple Interventional Research Trial by Eagle, Shawn R, Kontos, Anthony P, Collins, Michael W, Mucha, Anne, Holland, Cyndi L, Edelman, Kathryn, Benso, Steven, Schneider, Walter, Soose, Ryan, Okonkwo, David O

“…Mild traumatic brain injury (mTBI) and its potential long-term consequences is a primary concern for the US military. The purpose of the study is to evaluate…”
Get more information

Machine Learning Approaches for Integrating Clinical and Imaging Features in LLD Classification and Response Prediction by Patel, Meenal J., Andreescu, Carmen, Price, Julie C., Edelman, Kathryn L., Reynolds, Charles F., Aizenstein, Howard J.

Get full text

Impact of Multi-Disciplinary Care and Clinical Coach Coordinators on Participant Satisfaction and Retention in TBI Clinical Trials: A TEAM-TBI Study by Mesley, Matthew S, Edelman, Kathryn, Sharpless, Jane, Borrasso, Allison, Billigen, Julia B, Puffer, Ross, Williams, Dana, Benso, Steven, Puccio, Ava M, Schneider, Walt, Soose, Ryan, Beers, Sue, Kontos, Anthony, Collins, Michael, Okonkwo, David O

“…Abstract Background Targeted Evaluation Action and Monitoring of Traumatic Brain Injury (TEAM-TBI) is a monitored, multiple interventional research identifying…”
Get full text

[18F]FDG, [11C]PiB, and [18F]AV-1451 PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline by Okonkwo, David O, Puffer, Ross C, Minhas, Davneet S, Beers, Sue R, Edelman, Kathryn L, Sharpless, Jane, Laymon, Charles M, Lopresti, Brian J, Benso, Steven, Puccio, Ava M, Pathak, Sudhir, Ikonomovic, Milos D, Mettenburg, Joseph M, Schneider, Walter, Mathis, Chester A, Mountz, James M

Get full text