Search Results - "Eddie C. Y. Wang"

Oestrogen-deficiency induces bone loss by modulating CD14 + monocyte and CD4 + T cell DR3 expression and serum TL1A levels by Collins, Fraser L, Stone, Michael D, Turton, Jane, McCabe, Laura R, Wang, Eddie C Y, Williams, Anwen S

“…Oestrogen-deficiency induced by menopause is associated with reduced bone density and primary osteoporosis, resulting in an increased risk of fracture. While…”
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Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18 by Prod'homme, Virginie, Tomasec, Peter, Cunningham, Charles, Lemberg, Marius K, Stanton, Richard J, McSharry, Brian P, Wang, Eddie C Y, Cuff, Simone, Martoglio, Bruno, Davison, Andrew J, Braud, Véronique M, Wilkinson, Gavin W G

“…Human CMV (HCMV)-encoded NK cell-evasion functions include an MHC class I homolog (UL18) with high affinity for the leukocyte inhibitory receptor-1 (CD85j,…”
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Adenovirus E3/19K Promotes Evasion of NK Cell Recognition by Intracellular Sequestration of the NKG2D Ligands Major Histocompatibility Complex Class I Chain-Related Proteins A and B by MCSHARRY, Brian P, BURGERT, Hans-Gerhard, LITTLE, Ann-Margaret, WANG, Eddie C. Y, TOMASEC, Peter, WILKINSON, Gavin W. G, OWEN, Douglas P, STANTON, Richard J, PROD'HOMME, Virginie, SESTER, Martina, KOEBERNICK, Katja, GROH, Veronika, SPIES, Thomas, COX, Steven

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1- NK Cells by Prod'homme, Virginie, Griffin, Cora, Aicheler, Rebecca J, Wang, Eddie C. Y, McSharry, Brian P, Rickards, Carole R, Stanton, Richard J, Borysiewicz, Leszek K, Lopez-Botet, Miguel, Wilkinson, Gavin W. G, Tomasec, Peter

“…The inhibitory leukocyte Ig-like receptor 1 (LIR-1, also known as ILT2, CD85j, or LILRB1) was identified by its high affinity for the human CMV (HCMV) MHC…”
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IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection by Stacey, Maria A, Marsden, Morgan, Wang, Eddie C Y, Wilkinson, Gavin W G, Humphreys, Ian R

“…IL-10 is an immunomodulatory cytokine that acts to antagonize T cell responses elicited during acute and chronic infections. Thus, the IL-10R signaling pathway…”
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The cytokine receptor DR3 identifies and promotes the activation of thymic NKT17 cells by Luo, Shunqun, Liman, Nurcin, Li, Can, Crossman, Assiatu, Wang, Eddie C. Y., Meylan, Françoise, Park, Jung-Hyun

“…Invariant natural killer T ( i NKT) cells correspond to a population of thymus-generated T cells with innate-like characteristics and effector functions. Among…”
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Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex by Nightingale, Katie, Potts, Martin, Hunter, Leah M, Fielding, Ceri A, Zerbe, Cassie M, Fletcher-Etherington, Alice, Nobre, Luis, Wang, Eddie C Y, Strang, Blair L, Houghton, Jack W, Antrobus, Robin, Suarez, Nicolas M, Nichols, Jenna, Davison, Andrew J, Stanton, Richard J, Weekes, Michael P

“…Human cytomegalovirus (HCMV) is an important human pathogen and a paradigm of viral immune evasion, targeting intrinsic, innate, and adaptive immunity. We have…”
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Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation by Fielding, Ceri A, Aicheler, Rebecca, Stanton, Richard J, Wang, Eddie C Y, Han, Song, Seirafian, Sepehr, Davies, James, McSharry, Brian P, Weekes, Michael P, Antrobus, P Robin, Prod'homme, Virginie, Blanchet, Fabien P, Sugrue, Daniel, Cuff, Simone, Roberts, Dawn, Davison, Andrew J, Lehner, Paul J, Wilkinson, Gavin W G, Tomasec, Peter

“…NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating…”
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HCMV-Encoded NK Modulators: Lessons From in vitro and in vivo Genetic Variation by Patel, Mihil, Vlahava, Virginia-Maria, Forbes, Simone K, Fielding, Ceri A, Stanton, Richard J, Wang, Eddie C Y

“…Human cytomegalovirus (HCMV) is under constant selective pressure from the immune system . Study of HCMV genes that have been lost in the absence of, or…”
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Death Receptor 3 (TNFRSF25) Increases Mineral Apposition by Osteoblasts and Region Specific New Bone Formation in the Axial Skeleton of Male DBA/1 Mice by Williams, Anwen S., Choy, Ernest, Stone, Michael D., Bloom, Anja C., Williams, Jessica O., Collins, Fraser L., Wang, Eddie C. Y.

“…Objectives. Genome wide association studies identified TNFSF member TNF-like protein 1A (TL1A, TNFSF15) as a potential modulator of ankylosing spondylitis…”
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Review: Novel Insights Into Tumor Necrosis Factor Receptor, Death Receptor 3, and Progranulin Pathways in Arthritis and Bone Remodeling by Williams, Anwen, Wang, Eddie C. Y., Thurner, Lorenz, Liu, Chuan‐ju

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The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases by Meylan, Françoise, Davidson, Todd S., Kahle, Erin, Kinder, Michelle, Acharya, Krishika, Jankovic, Dragana, Bundoc, Virgilio, Hodges, Marcus, Shevach, Ethan M., Keane-Myers, Andrea, Wang, Eddie C.Y., Siegel, Richard M.

“…DR3 (TRAMP, LARD, WSL-1, TNFRSF25) is a death-domain-containing tumor necrosis factor (TNF)-family receptor primarily expressed on T cells. TL1A, the…”
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Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity by Omidvar, Nader, Wang, Eddie C. Y, Brennan, Paul, Longhi, M. Paula, Smith, Richard A. G, Morgan, B. Paul

“…NK cell-mediated cytotoxicity of target cells is the result of a balance between the activating and inhibitory signals provided by their respective…”
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Modulation of natural killer cells by human cytomegalovirus by Wilkinson, Gavin W.G, Tomasec, Peter, Stanton, Richard J, Armstrong, Melanie, Prod’homme, Virginie, Aicheler, Rebecca, McSharry, Brian P, Rickards, Carole R, Cochrane, Daniel, Llewellyn-Lacey, Sian, Wang, Eddie C.Y, Griffin, Cora A, Davison, Andrew J

“…Abstract Human cytomegalovirus (HCMV) causes lifelong, persistent infections and its survival is under intense, continuous selective pressure from the immune…”
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Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation by Lau, Betty, Kerr, Karen, Gu, Quan, Nightingale, Katie, Antrobus, Robin, Suárez, Nicolás M, Stanton, Richard J, Wang, Eddie C Y, Weekes, Michael P, Davison, Andrew J

“…Long non-coding RNAs (lncRNAs) are transcripts of >200 nucleotides that are not translated into functional proteins. Cellular lncRNAs have been shown to act as…”
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HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells by Stanton, Richard J., Prod’homme, Virginie, Purbhoo, Marco A., Moore, Melanie, Aicheler, Rebecca J., Heinzmann, Marcus, Bailer, Susanne M., Haas, Jürgen, Antrobus, Robin, Weekes, Michael P., Lehner, Paul J., Vojtesek, Borivoj, Miners, Kelly L., Man, Stephen, Wilkie, Gavin S., Davison, Andrew J., Wang, Eddie C.Y., Tomasec, Peter, Wilkinson, Gavin W.G.

“…Immune evasion genes help human cytomegalovirus (HCMV) establish lifelong persistence. Without immune pressure, laboratory-adapted HCMV strains have undergone…”
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The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro by McLaren, James E, Calder, Claudia J, McSharry, Brian P, Sexton, Keith, Salter, Rebecca C, Singh, Nishi N, Wilkinson, Gavin W G, Wang, Eddie C Y, Ramji, Dipak P

“…TNF-like protein 1A (TL1A), a TNF superfamily cytokine that binds to death receptor 3 (DR3), is highly expressed in macrophage foam cell-rich regions of…”
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Human Cytomegalovirus Glycoprotein UL141 Targets the TRAIL Death Receptors to Thwart Host Innate Antiviral Defenses by Smith, Wendell, Tomasec, Peter, Aicheler, Rebecca, Loewendorf, Andrea, Nemčovičová, Ivana, Wang, Eddie C.Y., Stanton, Richard J., Macauley, Matt, Norris, Paula, Willen, Laure, Ruckova, Eva, Nomoto, Akio, Schneider, Pascal, Hahn, Gabriele, Zajonc, Dirk M., Ware, Carl F., Wilkinson, Gavin W.G., Benedict, Chris A.

“…Death receptors (DRs) of the TNFR superfamily contribute to antiviral immunity by promoting apoptosis and regulating immune homeostasis during infection, and…”
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Regulation of Early Cartilage Destruction in Inflammatory Arthritis by Death Receptor 3 by Wang, Eddie C. Y., Newton, Zarabeth, Hayward, Olivia A., Clark, Stephen R., Collins, Fraser, Perks, William V., Singh, Ravinder K., Twohig, Jason P., Williams, Anwen S.

“…Objective To investigate the role of death receptor 3 (DR‐3) and its ligand tumor necrosis factor–like molecule 1A (TL1A) in the early stages of inflammatory…”
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TL1A Both Promotes and Protects from Renal Inflammation and Injury by AL-LAMKI, Rafia S, JUN WANG, POBER, Jordan S, BRADLEY, John R, TOLKOVSKY, Aviva M, BRADLEY, J. Andrew, GRIFFIN, Jules L, THIRU, Sathia, WANG, Eddie C. Y, BOLTON, Eleanor, WANG MIN, MOORE, Paul

“…Death receptor 3 (DR3), a member of the TNF receptor (TNFR) superfamily, is induced in human renal tubular epithelial cells (TEC) in response to injury. This…”
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