Search Results - "Edden, Richard A.E"

Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humans by Muthukumaraswamy, Suresh D, Edden, Richard A.E, Jones, Derek K, Swettenham, Jennifer B, Singh, Krish D

“…Functional imaging of the human brain is an increasingly important technique for clinical and cognitive neuroscience research, with functional MRI (fMRI) of…”
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GABA (gamma-aminobutyric acid) levels in dorsal anterior cingulate cortex are negatively associated with food motivation in a pediatric sample by Duck, Sarah Ann, Smith, Kimberly R., Saleh, Muhammad G., Jansen, Elena, Papantoni, Afroditi, Song, Yulu, Edden, Richard A.E., Carnell, Susan

“…Food motivation varies between individuals, affecting body weight and risk for eating disorders. Prior neuroimaging studies in youth and adults have revealed…”
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Reproducibility of brain spectroscopy at 7T using conventional localization and spectral editing techniques by Wijtenburg, S. Andrea, Rowland, Laura M., Edden, Richard A.E., Barker, Peter B.

“…Purpose To evaluate the reproducibility of spectroscopic measurements from the anterior cingulate (AC) and the dorsolateral prefrontal cortex (DLPFC) regions…”
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Measuring the longitudinal relaxation time of GABA in vivo at 3 tesla by Puts, Nicolaas A.J., Barker, Peter B., Edden, Richard A.E.

“…Purpose: To measure the in vivo longitudinal relaxation time T1 of GABA at 3 Tesla (T). Materials and Methods: J‐difference edited single‐voxel MR spectroscopy…”
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GABA levels in the ventromedial prefrontal cortex during the viewing of appetitive and disgusting food images by Padulo, Caterina, Pizzi, Stefano Delli, Bonanni, Laura, Edden, Richard A.E, Ferretti, Antonio, Marzoli, Daniele, Franciotti, Raffaella, Manippa, Valerio, Onofrj, Marco, Sepede, Gianna, Tartaro, Armando, Tommasi, Luca, Puglisi-Allegra, Stefano, Brancucci, Alfredo

“…Highlights • A decrease of GABA concentration in the vmPFC was observed during the observation of appetitive and disgusting food images. • No changes in Glx…”
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Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid-edited MR spectroscopy spectra by Edden, Richard A.E., Puts, Nicolaas A.J., Harris, Ashley D., Barker, Peter B., Evans, C. John

“…Purpose The purpose of this study is to describe the Gannet toolkit for the quantitative batch analysis of gamma‐aminobutyric acid (GABA) ‐edited MRS data…”
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Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data by Oeltzschner, Georg, Zöllner, Helge J., Hui, Steve C.N., Mikkelsen, Mark, Saleh, Muhammad G., Tapper, Sofie, Edden, Richard A.E.

“…•Osprey is an open-source analysis toolbox for magnetic resonance spectroscopy data.•Includes pre-processing, linear-combination modelling, and…”
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Tissue correction for GABA-edited MRS: Considerations of voxel composition, tissue segmentation, and tissue relaxations by Harris, Ashley D., Puts, Nicolaas A.J., Edden, Richard A.E.

“…Purpose To develop a tissue correction for GABA‐edited magnetic resonance spectroscopy (MRS) that appropriately addresses differences in voxel gray matter…”
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Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA by Mullins, Paul G., McGonigle, David J., O'Gorman, Ruth L., Puts, Nicolaas A.J., Vidyasagar, Rishma, Evans, C. John, Edden, Richard A.E.

“…There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held…”
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Regional balance between glutamate+glutamine and GABA+ in the resting human brain by Steel, Adam, Mikkelsen, Mark, Edden, Richard A.E., Robertson, Caroline E.

“…Models of healthy brain function and psychiatric conditions assume that excitatory and inhibitory activity are balanced in the human brain at multiple spatial…”
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Comparison of different linear‐combination modeling algorithms for short‐TE proton spectra by Zöllner, Helge J., Považan, Michal, Hui, Steve C.N., Tapper, Sofie, Edden, Richard A.E., Oeltzschner, Georg

“…Short‐TE proton MRS is used to study metabolism in the human brain. Common analysis methods model the data as a linear combination of metabolite basis spectra…”
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Comparison of methods for spectral alignment and signal modelling of GABA-edited MR spectroscopy data by Rideaux, Reuben, Mikkelsen, Mark, Edden, Richard A.E.

“…•Cr alignment produces GABA+ estimates more predictive of grey matter volume fraction than other alignment methods.•Cr alignment produces the fewest outliers,…”
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Dorsolateral Prefrontal γ-Aminobutyric Acid in Men Predicts Individual Differences in Rash Impulsivity by Boy, Frederic, Evans, C. John, Edden, Richard A.E, Lawrence, Andrew D, Singh, Krish D, Husain, Masud, Sumner, Petroc

“…Background Impulsivity is a multifaceted personality construct associated with numerous psychiatric disorders. Recent research has characterized four facets of…”
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GABA levels are differentially associated with bimanual motor performance in older as compared to young adults by Maes, Celine, Cuypers, Koen, Heise, Kirstin-Friederike, Edden, Richard A.E., Gooijers, Jolien, Swinnen, Stephan P.

“…•GABA levels were lower in older as compared to young adults for the SM1 voxel only.•The association between GABA levels and motor performance was…”
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Brain extended and closed forms glutathione levels decrease with age and extended glutathione is associated with visuospatial memory by Hu, Xin, Pan, Keyu, Zhao, Min, Lv, Jiali, Wang, Jing, Zhang, Xiaofeng, Liu, Yuxi, Song, Yulu, Gudmundson, Aaron T., Edden, Richard A.E., Ren, Fuxin, Zhang, Tao, Gao, Fei

“…•Decreased GSH levels with age in the PCC in a large cohort of 276 subjects.•The timecourse of GSH level in the PCC and ACC differed between males and…”
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Neurochemical and functional reorganization of the cognitive-ear link underlies cognitive impairment in presbycusis by Li, Ning, Ma, Wen, Ren, Fuxin, Li, Xiao, Li, Fuyan, Zong, Wei, Wu, Lili, Dai, Zongrui, Hui, Steve C.N., Edden, Richard A.E., Li, Muwei, Gao, Fei

“…•Auditory GABA levels and auditory network (AN)-DMN FC decreased in presbycusis.•Auditory GABA levels and AN-DMN FC mediated the cognitive-ear link in…”
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GABA levels and measures of intracortical and interhemispheric excitability in healthy young and older adults: an MRS-TMS study by Hermans, Lize, Levin, Oron, Maes, Celine, van Ruitenbeek, Peter, Heise, Kirstin-Friederike, Edden, Richard A.E., Puts, Nicolaas A.J., Peeters, Ronald, King, Bradley R., Meesen, Raf L.J., Leunissen, Inge, Swinnen, Stephan P., Cuypers, Koen

“…Edited magnetic resonance spectroscopy (MRS) and transcranial magnetic stimulation (TMS) have often been used to study the integrity of the GABAergic…”
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A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia by Coughlin, Jennifer M., Yang, Kun, Marsman, Anouk, Pradhan, Subechhya, Wang, Min, Ward, Rebecca E., Bonekamp, Susanne, Ambinder, Emily B., Higgs, Cecilia P., Kim, Pearl K., Edwards, Jamie A., Varvaris, Mark, Wang, Hongxing, Posporelis, Sotirios, Ma, Shuangchao, Tsujimura, Tsuyoshi, Edden, Richard A. E., Pomper, Martin G., Sedlak, Thomas W., Fournier, Margot, Schretlen, David J., Cascella, Nicola G., Barker, Peter B., Sawa, Akira

“…Involvement of oxidative stress in the pathophysiology of schizophrenia (SZ) is suggested by studies of peripheral tissue. Nonetheless, it is unclear how such…”
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Multimodal assessment of the GABA system in patients with fragile-X syndrome and neurofibromatosis of type 1 by Lacroix, Angelina, Proteau-Lemieux, Mélodie, Côté, Samantha, Near, Jamie, Hui, Steve C.N., Edden, Richard A.E., Lippé, Sarah, Çaku, Artuela, Corbin, François, Lepage, Jean-François

“…Fragile-X syndrome (FXS) and Neurofibromatosis of type 1 (NF-1) are two monogenic disorders sharing neurobehavioral symptoms and pathophysiological mechanisms…”
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Decreased auditory GABA+ concentrations in presbycusis demonstrated by edited magnetic resonance spectroscopy by Gao, Fei, Wang, Guangbin, Ma, Wen, Ren, Fuxin, Li, Muwei, Dong, Yuling, Liu, Cheng, Liu, Bo, Bai, Xue, Zhao, Bin, Edden, Richard A.E.

“…Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the central auditory system. Altered GABAergic neurotransmission has been found in…”
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