Search Results - "Edde, Bernard"

Polyglutamylation Is a Post-translational Modification with a Broad Range of Substrates by van Dijk, Juliette, Miro, Julie, Strub, Jean-Marc, Lacroix, Benjamin, van Dorsselaer, Alain, Edde, Bernard, Janke, Carsten

“…Polyglutamylation is a post-translational modification that generates lateral acidic side chains on proteins by sequential addition of glutamate amino acids…”
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A Targeted Multienzyme Mechanism for Selective Microtubule Polyglutamylation by van Dijk, Juliette, Rogowski, Krzysztof, Miro, Julie, Lacroix, Benjamin, Eddé, Bernard, Janke, Carsten

“…Polyglutamylases are enzymes that form polyglutamate side chains of variable lengths on proteins. Polyglutamylation of tubulin is believed to regulate…”
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Tubulin Polyglutamylase Enzymes Are Members of the TTL Domain Protein Family by Janke, Carsten, Rogowski, Krzysztof, Wloga, Dorota, Regnard, Catherine, Kajava, Andrey V, Strub, Jean-Marc, Temurak, Nevzat, van Dijk, Juliette, Boucher, Dominique, van Dorsselaer, Alain, Suryavanshi, Swati, Gaertig, Jacek, Eddé, Bernard

“…Polyglutamylation of tubulin has been implicated in several functions of microtubules, but the identification of the responsible enzyme(s) has been…”
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Tubulin Glutamylation Regulates Ciliary Motility by Altering Inner Dynein Arm Activity by Suryavanshi, Swati, Eddé, Bernard, Fox, Laura A., Guerrero, Stella, Hard, Robert, Hennessey, Todd, Kabi, Amrita, Malison, David, Pennock, David, Sale, Winfield S., Wloga, Dorota, Gaertig, Jacek

“…How microtubule-associated motor proteins are regulated is not well understood. A potential mechanism for spatial regulation of motor proteins is provided by…”
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Glutamylation on α-Tubulin Is Not Essential but Affects the Assembly and Functions of a Subset of Microtubules in Tetrahymena thermophila by Wloga, Dorota, Rogowski, Krzysztof, Sharma, Neeraj, Van Dijk, Juliette, Janke, Carsten, Eddé, Bernard, Bré, Marie-Hélène, Levilliers, Nicolette, Redeker, Virginie, Duan, Jianming, Gorovsky, Martin A, Jerka-Dziadosz, Maria, Gaertig, Jacek

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterisation of PGs1, a subunit of a protein complex co-purifying with tubulin polyglutamylase by Regnard, Catherine, Fesquet, Didier, Janke, Carsten, Boucher, Dominique, Desbruyéres, Elisabeth, Koulakoff, Annette, Insina, Christine, Travo, Pierre, Eddé, Bernard

“…Polyglutamylation is a post-translational modification initially discovered on tubulin. It has been implicated in multiple microtubule functions, including…”
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Ilf3 and NF90 associate with the axonal targeting element of Tau mRNA by Larcher, Jean-Christophe, Gasmi, Laila, Viranaïcken, Wildriss, Eddé, Bernard, Bernard, Rozenn, Ginzburg, Irith, Denoulet, Philippe

“…ABSTRACT In neurons, the selective translocation of Tau mRNA toward axons is due to the presence of a nucleotide sequence located in its 3′ untranslated region…”
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Polyglutamylation of Nucleosome Assembly Proteins by Regnard, Catherine, Desbruyères, Elisabeth, Huet, Jean-Claude, Beauvallet, Christian, Pernollet, Jean-Claude, Eddé, Bernard

“…Polyglutamylation is an original posttranslational modification, discovered on tubulin, consisting in side chains composed of several glutamyl units and…”
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The polyglutamylated lateral chain of alpha-tubulin plays a key role in flagellar motility by Gagnon, C, White, D, Cosson, J, Huitorel, P, Eddé, B, Desbruyères, E, Paturle-Lafanechère, L, Multigner, L, Job, D, Cibert, C

“…To investigate whether a specific isotype of tubulin is involved in flagellar motility, we have developed and screened a panel of monoclonal antibodies (mAb)…”
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Posttranslational Glutamylation of α-Tubulin by Eddé, Bernard, Rossier, Jean, Le Caer, Jean-Pierre, Desbruyères, Elizabeth, Gros, François, Denoulet, Philippe

“…The high degree of tubulin heterogeneity in neurons is controlled mainly at the posttranslational level. Several variants of α-tubulin can be…”
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Characterization of a major brain tubulin variant which cannot be tyrosinated by Paturle-Lafanechere, Laurence, Edde, Bernard, Denoulet, Philippe, Van Dorsselaer, Alain, Mazarguil, Honore, Le Caer, Jean Pierre, Wehland, Juergen, Job, Didier

“…Brain tubulin preparations contain an abundant type of tubulin which does not undergo the normal cycle of tyrosination-detyrosination, and whose nature is…”
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Polyglutamylation is a posttranslational modification with a broad range of substrates by van Dijk, Juliette, Miro, Julie, Strub, Jean-Marc, Lacroix, Benjamin, van Dorsselaer, Alain, Edde, Bernard, Janke, Carsten

“…Polyglutamylation is a posttranslational modification that generates lateral acidic side chains on proteins by sequential addition of glutamate amino acids…”
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Glutamylation on -Tubulin Is Not Essential but Affects the Assembly and Functions of a Subset of Microtubules in Tetrahymena thermophila by Wloga, Dorota, Rogowski, Krzysztof, Sharma, Neeraj, Dijk, Juliette Van, Janke, Carsten, Edde, Bernard, Bre, Marie-Helene, Levilliers, Nicolette, Redeker, Virginie, Duan, Jianming, Gorovsky, Martin A, Jerka-Dziadosz, Maria, Gaertig, Jacek

“…Tubulin undergoes glutamylation, a conserved posttranslational modification of poorly understood function. We show here that in the ciliate Tetrahymena, most…”
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Differential distribution of glutamylated tubulin during spermatogenesis in mammalian testis by Fouquet, J P, Edde, B, Kann, M L, Wolff, A, Desbruyeres, E, Denoulet, P

“…The distribution of glutamylated tubulin has been analyzed in mammalian testis using the specific mAb GT335 by immunoelectron microscopy and immunoblotting. In…”
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Polyglutamylated .alpha.-tubulin can enter the tyrosination/detyrosination cycle by Edde, Bernard, Rossier, Jean, Le Caer, Jean Pierre, Prome, Jean Claude, Desbruyeres, Elisabeth, Gros, Francois, Denoulet, Philippe

“…We have previously identified a major modification of neuronal alpha-tubulin which consists of the posttranslational addition of a varying number of glutamyl…”
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Posttranslational Glutamylation of (alpha)-Tubulin by Edde, Bernard, Rossier, Jean, Gros, Francois, Denoulet, Philippe, Desbruyeres, Elizabeth

“…Amino acid analysis, Edman degradation sequencing, and mass spectrometric analysis of the alpha-tubulin, a neuron in the brain, suggested that such peptides…”
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Evolution of tubulin heterogeneity during mouse brain development by Denoulet, P, Edde, B, Jeantet, C, Gros, F

“…In this report, we have characterized tubulin subunit heterogeneity and its evolution during mouse brain development, from embryonic to adult stages. A…”
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Developmental regulation of polyglutamylated alpha- and beta-tubulin in mouse brain neurons by Audebert, S, Koulakoff, A, Berwald-Netter, Y, Gros, F, Denoulet, P, Eddé, B

“…Polyglutamylation is an important posttranslational modification of tubulin that is very active in nerve cells, where it accounts for the main factor…”
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Reversible polyglutamylation of α- and β-tubulin and microtubule dynamics in mouse brain neurons by AUDEBERT, S, DESBRUYERES, E, GRUSZCZYNSKI, C, KOULAKOFF, A, GROS, F, DENOULET, P, EDDE, B

“…The relationship between microtubule dynamics and polyglutamylation of tubulin was investigated in young differentiating mouse brain neurons. Selective…”
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Changes in some cytoskeletal proteins during neuroblastoma cell differentiation by Edde, B, Portier, M M, Sahuquillo, C, Jeantet, C, Gros, F

“…After in vitro microtubule assembly of mouse neuroblastoma crude extracts, six protein species migrate in the tubulin region of two-dimensional…”
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