Search Results - "Edatt, Lincy"

Horizontal transfer of miR‐23a from hypoxic tumor cell colonies can induce angiogenesis by Sruthi, T. V., Edatt, Lincy, Raji, Grace R., Kunhiraman, Haritha, Shankar, Sharath S., Shankar, Vandana, Ramachandran, Vishnu, Poyyakkara, Aswini, Kumar, Sameer V. B.

“…Neo vessel formation by angiogenesis is an important event during many pathological conditions including cancer, where it is indispensable for tumor growth and…”
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Regulation of poly ADP-ribosylation of VEGF by an interplay between PARP-16 and TNKS-2 by Kunhiraman, Haritha, Ramachandran, Vishnu, Edatt, Lincy, Sameer Kumar, V. B.

“…The biological activity of vascular endothelial growth factor (VEGF), the major cytokine regulating the process of angiogenesis is tightly controlled at…”
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Horizontal transfer of miR-106a/b from cisplatin resistant hepatocarcinoma cells can alter the sensitivity of cervical cancer cells to cisplatin by Raji, Grace R., Sruthi, T.V., Edatt, Lincy, Haritha, K., Sharath Shankar, S., Sameer Kumar, V.B.

“…Recent studies indicate that horizontal transfer of genetic material can act as a communication tool between heterogenous populations of tumour cells, thus…”
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Role of Sirtuins in Tumor Angiogenesis by Edatt, Lincy, Poyyakkara, Aswini, Raji, Grace R, Ramachandran, Vishnu, Shankar, S Sharath, Kumar, V B Sameer

“…Generally, changes in the metabolic status of cells under conditions like hypoxia and accumulation of lactate can be sensed by various sensing mechanisms,…”
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Study of In vitro antioxidant and DNA damage protection activity of a novel luteolin derivative isolated from Terminalia chebula by Soumya, K., Haridas, Karickal R., James, Jesna, Sameer Kumar, V. B., Edatt, Lincy, Sudheesh, S.

“…The present study aimed to investigate the efficacy of flavonoids isolated from the fruit of Terminalia chebula against the hydrogen peroxide-induced DNA…”
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Periostin+ Stromal Cells Guide Lymphovascular Invasion by Cancer Cells by Null, Jamie L, Kim, Dae Joong, McCann, James V, Pramoonjago, Patcharin, Fox, Jay W, Zeng, Jianhao, Kumar, Pankaj, Edatt, Lincy, Pecot, Chad V, Dudley, Andrew C

“…Cancer cell dissemination to sentinel lymph nodes is associated with poor patient outcomes, particularly in breast cancer. The process by which cancer cells…”
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Horizontal transfer of miR-383 sensitise cells to cisplatin by targeting VEGFA-Akt signalling loop by Raji, Grace R., Poyyakkara, Aswini, Sruthi, T. V., Edatt, Lincy, Haritha, K., Shankar, S. Sharath, Kumar, V. B. Sameer

“…Background Cellular resistance to cisplatin has been one of the major obstacles in the success of combination therapy for many types of cancers. Emerging…”
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ER stress mediated regulation of miR23a confer Hela cells better adaptability to utilize glycolytic pathway by Poyyakkara, Aswini, Raji, Grace R., Kunhiraman, Haritha, Edatt, Lincy, Kumar, Sameer V.B.

“…Cancer cells exhibit increased dependency on aerobic glycolysis, a phenomenon referred as the “Warburg effect” and therefore, blocking glycolysis by using…”
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Integrin β4 induced epithelial-to-mesenchymal transition involves miR-383 mediated regulation of GATA6 levels by Poyyakkara, Aswini, Raji, Grace R., Padmaja, K. P., Ramachandran, Vishnu, Changmai, Udeshna, Edatt, Lincy, Punathil, Rabina, Kumar, V. B. Sameer

“…Background The process of transdifferentiating epithelial cells to mesenchymal-like cells (EMT) involves cells gradually taking on an invasive and migratory…”
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MicroRNA106a regulates matrix metalloprotease 9 in a sirtuin‐1 dependent mechanism by Edatt, Lincy, Maurya, Ashutosh K., Raji, Grace, Kunhiraman, Haritha, Kumar, Sameer V. B.

“…Cellular migration is important during many physiological as well as pathological conditions and is regulated very tightly by an intricate network of signaling…”
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2‐Deoxy Glucose Modulates Expression and Biological Activity of VEGF in a SIRT‐1 Dependent Mechanism by Kunhiraman, Haritha, Edatt, Lincy, Thekkeveedu, Sruthi, Poyyakkara, Aswini, Raveendran, Viji, Kiran, Manikantan Syamala, Sudhakaran, Perumana, Kumar, Sameer V.B.

“…ABSTRACT Reprogramming of energy metabolism particularly switching over of cells to aerobic glycolysis leading to accumulation of lactate is a hallmark of…”
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Modulation of digestive enzymes, GH, IGF-1 and IGF-2 genes in the teleost, Tilapia (Oreochromis mossambicus) by dietary curcumin by Midhun, Sebastian J., Arun, Damodaran, Edatt, Lincy, Sruthi, M. V., Thushara, V. V., Oommen, Oommen V., Sameer Kumar, V. B., Divya, Lekha

“…Aquaculture is faced with the challenges of the use of synthetic compounds as growth enhancers and the presence of several contaminants in water. These factors…”
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Synthesis of Novel Quin[1,2-b]Acridines: In Vitro Cytotoxicity and Molecular Docking Studies by Satheeshkumar, Rajendran, Edatt, Lincy, Muthusankar, Aathi, Sameer Kumar, V. B., Rajendra Prasad, Karnam Jayarampillai

“…An attempted synthesis of 5-aryl-6,7-dihydrodibenzo[b,j][1,10]phenanthroline derivatives from 2,3-dihydroacridin-4(1H)-ones with 2-aminocarboxylic acid…”
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2-Deoxy Glucose Modulates Expression and Biological Activity of VEGF in a SIRT-1 Dependent Mechanism: R EGULATION OF VEGF BY 2-DG by Kunhiraman, Haritha, Edatt, Lincy, Thekkeveedu, Sruthi, Poyyakkara, Aswini, Raveendran, Viji, Kiran, Manikantan Syamala, Sudhakaran, Perumana, Kumar, Sameer V.B.

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2-Deoxy glucose regulate MMP-9 in a SIRT-1 dependent and NFkB independent mechanism by Edatt, Lincy, Haritha, K., Sruthi, T. V., Aswini, P., Sameer Kumar, V. B.

“…MMP9 is a member of the family of zinc-containing endopeptidases which degrade various components of the extracellular matrix, thereby regulating matrix…”
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Spon1+ inflammatory monocytes promote collagen remodeling and lung cancer metastasis through lipoprotein receptor 8 signaling by Whately, Kristina M, Sengottuvel, Nisitha, Edatt, Lincy, Srivastava, Sonal, Woods, Allison T, Tsai, Yihsuan S, Porrello, Alessandro, Zimmerman, Matthew P, Chack, Aaron C, Jefferys, Stuart R, Yacovone, Gabriella, Kim, Dae Joong, Dudley, Andrew C, Amelio, Antonio L, Pecot, Chad V

“…Lung cancer is the leading cause of cancer-related deaths in the world, and non-small cell lung cancer (NSCLC) is the most common subset. We previously found…”
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Synthesis of heteroannulated cyclopent[b]indoles: Exploration of in vitro cytotoxicity and molecular docking studies by Satheeshkumar, Rajendran, Muthusankar, Aathi, Edatt, Lincy, Sameer Kumar, V. B., Sparkes, Hazel A., Rajendra Prasad, Karnam Jayarampillai

“…A series of novel cyclopent[b]indole analogues that hold isoxazolo-, pyrido-templates were designed and synthesized in good yields. The in vitro cytotoxicity…”
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A Facile Regioselective Synthesis of New Class of Cyclopent[b]indole dispiro heterocycles via1,3‐Dipolar Cycloaddition protocol and in vitro Cytotoxic studies by Satheeshkumar, Rajendran, Edatt, Lincy, Kumar, V. B. Sameer, Prasad, Karnam Jayarampillai Rajendra

“…The construction of azomethine ylides in situ from acenaphthoquinone/isatin and secondary amino acids such as sarcosine and thiaproline with cyclopent[b]indole…”
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