Search Results - "Edassery, Seby L."

Inflammasome expression is higher in ovarian tumors than in normal ovary by Luborsky, Judith, Barua, Animesh, Edassery, Seara, Bahr, Janice M, Edassery, Seby L

“…Chronic inflammation fundamentally influences cancer risk and development. A mechanism of chronic inflammation is the formation of inflammasome complexes which…”
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Proteomic profiling of regenerated urinary bladder tissue in a non-human primate augmentation model by Sharma, Tiffany T., Edassery, Seby L., Rajinikanth, Nachiket, Karra, Vikram, Bury, Matthew I., Sharma, Arun K.

“…Urinary bladder dysfunction can be caused by environmental, genetic, and developmental insults. Depending upon insult severity, the bladder may lose its…”
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Cotransplantation with specific populations of spina bifida bone marrow stem/progenitor cells enhances urinary bladder regeneration by Sharma, Arun K., Bury, Matthew I., Fuller, Natalie J., Marks, Andrew J., Kollhoff, David M., Rao, Manoj V., Hota, Partha V., Matoka, Derek J., Edassery, Seby L., Thaker, Hatim, Sarwark, John F., Janicki, Joseph A., Ameer, Guillermo A., Cheng, Earl Y.

“…Spina bifida (SB) patients afflicted with myelomeningocele typically possess a neurogenic urinary bladder and exhibit varying degrees of bladder dysfunction…”
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BET1 variants establish impaired vesicular transport as a cause for muscular dystrophy with epilepsy by Donkervoort, Sandra, Krause, Niklas, Dergai, Mykola, Yun, Pomi, Koliwer, Judith, Gorokhova, Svetlana, Geist Hauserman, Janelle, Cummings, Beryl B, Hu, Ying, Smith, Rosemarie, Uapinyoying, Prech, Ganesh, Vijay S, Ghosh, Partha S, Monaghan, Kristin G, Edassery, Seby L, Ferle, Pia E, Silverstein, Sarah, Chao, Katherine R, Snyder, Molly, Ellingwood, Sara, Bharucha‐Goebel, Diana, Iannaccone, Susan T, Dal Peraro, Matteo, Foley, A Reghan, Savas, Jeffrey N, Bolduc, Véronique, Fasshauer, Dirk, Bönnemann, Carsten G, Schwake, Michael

“…BET1 is required, together with its SNARE complex partners GOSR2, SEC22b, and Syntaxin‐5 for fusion of endoplasmic reticulum‐derived vesicles with the ER‐Golgi…”
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Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure by Edassery, Seby L., M.S, Shatavi, Seerin V., M.D, Kunkel, Jeremy P., Ph.D, Hauer, Charles, Ph.D, Brucker, Cosima, M.D, Penumatsa, Krishna, M.S, Yu, Yi, M.S, Dias, James A., Ph.D, Luborsky, Judith L., Ph.D

“…Objective To identify ovarian autoantigens associated with ovarian autoantibodies. Design Hypothesis-generating prospective study. Setting Urban infertility…”
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Immune cells in the normal ovary and spontaneous ovarian tumors in the laying hen (Gallus domesticus) model of human ovarian cancer by Bradaric, Michael J, Penumatsa, Krishna, Barua, Animesh, Edassery, Seby L, Yu, Yi, Abramowicz, Jacques S, Bahr, Janice M, Luborsky, Judith L

“…Spontaneous ovarian cancer in chickens resembles human tumors both histologically and biochemically. The goal was to determine if there are differences in…”
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Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors by Penumatsa, Krishna, Edassery, Seby L, Barua, Animesh, Bradaric, Michael J, Luborsky, Judith L

“…We showed there are specific ALDH1 autoantibodies in ovarian autoimmune disease and ovarian cancer, suggesting a role for ALDH1 in ovarian pathology. However,…”
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Long-lived mitochondrial cristae proteins in mouse heart and brain by Bomba-Warczak, Ewa, Edassery, Seby L, Hark, Timothy J, Savas, Jeffrey N

“…Long-lived proteins (LLPs) have recently emerged as vital components of intracellular structures whose function is coupled to long-term stability. Mitochondria…”
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Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model by Barua, Animesh, Abramowicz, Jacques S., Edassery, Seby, Bahr, Janice M., Bitterman, Pincas, McNeal, Sa’Rah, Basu, Sanjib

“…Ovarian cancer (OVCA) mainly disseminates in the peritoneal cavity. Immune functions are important to prevent OVCA progression and recurrence. The mechanism of…”
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Mitochondrial calcium uniporter deletion prevents painful diabetic neuropathy by restoring mitochondrial morphology and dynamics by George, Dale S., Hackelberg, Sandra, Jayaraj, Nirupa D., Ren, Dongjun, Edassery, Seby L., Rathwell, Craig A., Miller, Rachel E., Malfait, Anne-Marie, Savas, Jeffrey N., Miller, Richard J., Menichella, Daniela M.

“…Painful diabetic neuropathy (PDN) is an intractable complication affecting 25% of diabetic patients. Painful diabetic neuropathy is characterized by…”
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Prevalence of antitumor antibodies in laying hen model of human ovarian cancer by Barua, Animesh, Edassery, Seby L, Bitterman, Pincas, Abramowicz, Jacques S, Dirks, Angela L, Bahr, Janice M, Hales, Dale B, Bradaric, Michael J, Luborsky, Judith L

“…Antitumor antibodies are associated with tumors in human cancers. There is relatively little information on the timing and progression of antibody response to…”
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Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis by Tsioras, Konstantinos, Smith, Kevin C., Edassery, Seby L., Garjani, Mehraveh, Li, Yichen, Williams, Chloe, McKenna, Elizabeth D., Guo, Wenxuan, Wilen, Anika P., Hark, Timothy J., Marklund, Stefan L., Ostrow, Lyle W., Gilthorpe, Jonathan D., Ichida, Justin K., Kalb, Robert G., Savas, Jeffrey N., Kiskinis, Evangelos

“…Mutations in SOD1 cause amyotrophic lateral sclerosis (ALS) through gain-of-function effects, yet the mechanisms by which misfolded mutant SOD1 (mutSOD1)…”
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Selenium-Binding Protein 1 (SBP1) autoantibodies in ovarian disorders and ovarian cancer by Yu-Rice, Yi, Edassery, Seby L, Urban, Nicole, Hellstrom, Ingegerd, Hellstrom, Karl Erik, Deng, Youping, Li, Yan, Luborsky, Judith L

“…Infertility is a risk factor for ovarian cancer (OvCa). The goal was to determine if antibodies to selenium-binding protein 1 (SBP1), an autoantibody we…”
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The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors by Yu, Yi, Edassery, Seby L, Barua, Animesh, Abramowicz, Jacques S, Bahr, Janice M, Hellstrom, Ingegerd, Luborsky, Judith L

“…Study of the hen immune system led to seminal contributions to basic immunological principles. Recent studies of spontaneous ovarian cancer in the laying hen…”
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Sphingosine-1 phosphate receptor (S1p1), a critical receptor controlling human lymphocyte trafficking, is expressed in hen and human ovaries and ovarian tumors by Bradaric, Michael J, Barua, Animesh, Penumatsa, Krishna, Yi, Yu, Edassery, Seby L, Sharma, Sameer, Abramowicz, Jacques S, Bahr, Janice M, Luborsky, Judith L

“…Sphingosine-1 receptor 1 (S1P1) plays a major role in regulating lymphocyte egress from peripheral lymph tissue. Lymphocyte trafficking is potentially a…”
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Histopathology of ovarian tumors in laying hens: a preclinical model of human ovarian cancer by Barua, Animesh, Bitterman, Pincas, Abramowicz, Jacques S, Dirks, Angela L, Bahr, Janice M, Hales, Dale B, Bradaric, Michael J, Edassery, Seby L, Rotmensch, Jacob, Luborsky, Judith L

“…The high mortality rate due to ovarian cancer (OVCA) is attributed to the lack of an effective early detection method. Because of the nonspecificity of…”
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Enhancement of Ovarian Tumor Detection by DR6-Targeted Ultrasound Imaging Agents in Laying Hen Model of Spontaneous Ovarian Cancer by Barua, Animesh, Edassery, Seby L, McNeal, Sa'Rah, Bahr, Janice M, Bitterman, Pincas, Basu, Sanjib, Sharma, Sameer, Abramowicz, Jacques S

“…The lack of an effective early detection test leads to high case to death ratio of women with ovarian cancer (OVCA). To improve early detection,…”
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Multipotent bone marrow cell-seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration by Bury, Matthew I, Fuller, Natalie J, Wang, Xinlong, Chan, Yvonne Y, Sturm, Renea M, Oh, Sang Su, Sofer, Laurel A, Arora, Hans C, Sharma, Tiffany T, Nolan, Bonnie G, Feng, Wei, Rabizadeh, Rebecca R, Barac, Milica, Edassery, Sonia S, Goedegebuure, Madeleine M, Wang, Larry W, Ganesh, Balaji, Halliday, Lisa C, Seniw, Mark E, Edassery, Seby L, Mahmud, Nadim B, Hofer, Matthias D, McKenna, Kevin E, Cheng, Earl Y, Ameer, Guillermo A, Sharma, Arun K

“…To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies, including urinary diversion…”
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Association of interleukin 16 with the development of ovarian tumor and tumor-associated neoangiogenesis in laying hen model of spontaneous ovarian cancer by Yellapa, Aparna, Bahr, Janice M, Bitterman, Pincas, Abramowicz, Jacques S, Edassery, Seby L, Penumatsa, Krishna, Basu, Sanjib, Rotmensch, Jacob, Barua, Animesh

“…Tumor-associated neoangiogenesis (TAN) is an early event in ovarian tumor development. Interleukin 16 (IL-16) is a proangiogenic cytokine that stimulates…”
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Selenium-Binding Protein 1 expression in ovaries and ovarian tumors in the laying hen, a spontaneous model of human ovarian cancer by Stammer, Karen, Edassery, Seby L, Barua, Animesh, Bitterman, Pincas, Bahr, Janice M, Hales, Dale Buchanan, Luborsky, Judith L

“…Abstract Objective. Reduced Selenium-Binding Protein 1 (SELENBP1) expression was recently shown in multiple cancers. There is little information on the…”
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