Search Results - "Econs, M J"

Evaluation of vertebral fracture assessment by dual X-ray absorptiometry in a multicenter setting by Fuerst, T, Wu, C, Genant, H. K, von Ingersleben, G, Chen, Y, Johnston, C, Econs, M. J, Binkley, N, Vokes, T. J, Crans, G, Mitlak, B. H

“…Summary The utility of vertebral fracture assessment (VFA) by DXA to detect prevalent vertebral fracture in a multicenter setting was investigated by…”
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FGF-23 Is Elevated by Chronic Hyperphosphatemia by Gupta, A., Winer, K., Econs, M. J., Marx, S. J., Collins, M. T.

“…The Identification and characterization of FGF-23 has provided an opportunity to gain new insight into phosphorus metabolism. Circulating FGF-23 promotes renal…”
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Race and sex differences in bone mineral density and geometry at the femur by Peacock, M, Buckwalter, K.A, Persohn, S, Hangartner, T.N, Econs, M.J, Hui, S

“…Abstract Introduction Differences in osteoporotic hip fracture incidence between American whites and blacks and between women and men are considered to result,…”
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Effect of raloxifene after recombinant teriparatide [hPTH(1–34)] treatment in postmenopausal women with osteoporosis by Adami, S., San Martin, J., Muñoz-Torres, M., Econs, M. J., Xie, L., Dalsky, G. P., McClung, M., Felsenberg, D., Brown, J. P., Brandi, M. L., Sipos, A.

“…Summary Loss of bone mineral density occurs after discontinuation of teriparatide, if no subsequent treatment is given. Sequential raloxifene prevented rapid…”
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Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis by KOLLER, D. L, ECONS, M. J, PEACOCK, M, JOHNSTON, C. C, FOROUD, T, MORIN, P. A, CHRISTIAN, J. C, HUI, S. L, PARRY, P, CURRAN, M. E, RODRIGUEZ, L. A, CONNEALLY, P. M, JOSLYN, G

“…A major determinant of the risk for osteoporosis is peak bone mineral density (BMD), which is largely determined by genetic factors. We recently reported…”
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Resolution of severe, adolescent-onset hypophosphatemic rickets following resection of an FGF-23-producing tumour of the distal ulna by Ward, L.M, Rauch, F, White, K.E, Filler, G, Matzinger, M.A, Letts, M, Travers, R, Econs, M.J, Glorieux, F.H

“…Oncogenic hypophosphatemic osteomalacia (OHO) is an uncommon hypophosphatemic syndrome characterized by bone pain, proximal muscle weakness and rickets. It has…”
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Pex Gene Deletions in Gy and Hyp Mice Provide Mouse Models for X-Linked Hypophosphatemia by Strom, Tim M., Francis, Fiona, Lorenz, Bettina, Böddrich, Annett, Lehrach, Hans, Econs, Michael J., Meitinger, Thomas

“…X-linked hypophosphatemic rickets in humans is caused by mutations in the PEX gene which codes for a protein homologous to neutral endopeptidases. Hyp and Gy…”
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MEPE, a New Gene Expressed in Bone Marrow and Tumors Causing Osteomalacia by Rowe, Peter S.N, de Zoysa, Priyal A, Dong, Rong, Wang, Huei Rong, White, Kenneth E, Econs, Michael J, Oudet, Claudine L

“…Oncogenic hypophosphatemic osteomalacia (OHO) is characterized by a renal phosphate leak, hypophosphatemia, low-serum calcitriol (1,25-vitamin-D3), and…”
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Association studies of ALOX5 and bone mineral density in healthy adults by Foroud, T., Ichikawa, S., Koller, D., Lai, D., Curry, L., Xuei, X., Edenberg, H. J., Hui, S., Peacock, M., Econs, M. J.

“…Summary Animal studies suggest that arachidonate 5-lipoxygenase (encoded by ALOX5) may be a genetic determinant of bone mineral density. We tested this…”
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Osteoglophonic dysplasia: A 'common' mutation in a rare disease by Sow, AJ, Ramli, R, Latiff, ZA, Ichikawa, S, Gray, AK, Nordin, R, Abd Jabar, MN, Primuharsa Putra, SHA, Siar, CH, Econs, MJ

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Autosomal Dominant Hypophosphatemic Rickets/Osteomalacia: Clinical Characterization of a Novel Renal Phosphate-Wasting Disorder by Econs, Michael J, McEnery, Paul T

“…Renal phosphate-wasting disorders are the most common form of hereditary rickets and osteomalacia in western countries. Although autosomal dominant…”
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Identification of a quantitative trait locus on rat chromosome 4 that is strongly linked to femoral neck structure and strength by Alam, I., Sun, Q., Liu, L., Koller, D.L., Fishburn, T., Carr, L.G., Econs, M.J., Foroud, T., Turner, C.H.

“…Risk factors for osteoporotic hip fracture include reduced bone mineral density and poor structure of the femoral neck, both of which are heritable traits…”
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Linkage of a QTL Contributing to Normal Variation in Bone Mineral Density to Chromosome 11q12–13 by Koller, D. L., Rodriguez, L. A., Christian, J. C., Slemenda, C. W., Econs, M. J., Hui, S. L., Morin, P., Conneally, P. M., Joslyn, G., Curran, M. E., Peacock, M., Johnston, C. C., Foroud, T.

“…Osteoporosis is a leading public health problem that is responsible for substantial morbidity and mortality. A major determinant of the risk for osteoporosis…”
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New insights into the pathogenesis of inherited phosphate wasting disorders by Econs, M.J.

“…X-linked hypophosphatemic rickets and autosomal dominant hypophosphatemic rickets are inherited phosphate wasting disorders. X-linked hypophosphatemic rickets…”
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Linkage of Structure at the Proximal Femur to Chromosomes 3, 7, 8, and 19 by Koller, Dl, White, Ke, Liu, G, Hui, Sl, Conneally, Pm, Johnston, Cc, Econs, Mj, Foroud, T, Peacock, M

“…Risk for osteoporotic fracture is determined in part by femoral structure, which is under genetic control. We conducted a genome scan in 638 sister‐pairs for…”
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Polymorphisms in the bone morphogenetic protein 2 (BMP2) gene do not affect bone mineral density in white men or women by ICHIKAWA, S, JOHNSON, M. L, KOLLER, D. L, LAI, D, XUEI, X, EDENBERG, H. J, HUI, S. L, FOROUD, T. M, PEACOCK, M, ECONS, M. J

“…Peak bone mineral density (BMD) achieved during adulthood is a major determinant of osteoporotic fracture in later life. Although environmental factors affect…”
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Tumor-Induced Osteomalacia -- Unveiling a New Hormone by Econs, Michael J, Drezner, Marc K

“…Phosphate plays a critical part in the regulation of cell metabolism, and phosphate homeostasis is closely regulated in normal humans. Indeed, like serum…”
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Distribution of Mutations in the PEX Gene in Families with X-linked Hypophosphataemic Rickets (HYP) by Rowe, Peter S. N., Oudet, Claudine L., Francis, Fiona, Sinding, Christiane, Pannetier, Solange, Econs, Mike J., Strom, Tim M., Meitinger, Thomas, Garabedian, Michele, David, Albert, Macher, Marie-Alice, Questiaux, Elisabeth, Popowska, Ewa, Pronicka, Ewa, Read, Andrew P., Mokrzycki, Agnes, Glorieux, Francis H., Drezner, Marc K., Hanauer, Andre, Lehrach, Hans, Goulding, Johnathan N., O'Riordan, Jeffrey L. H.

“…Mutations in the PEXgene at Xp22.1 (phosphate-regulating gene with homologies to endopeptidases, on the X-chromosome), are responsible for X-linked…”
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A PHEX gene mutation is responsible for adult-onset vitamin D-resistant hypophosphatemic osteomalacia : Evidence that the disorder is not a distinct entity from X-linked hypophosphatemic rickets by ECONS, M. J, FRIEDMAN, N. E, BERGEN, H, ROWE, P. S. N, SPEER, M. C, FRANCIS, F, STROM, T. M, OUDET, C, SMITH, J. A, NINOMIYA, J. T, LEE, B. E

“…Previous investigators described a kindred with an X-linked dominant form of phosphate wasting in which affected children did not have radiographic evidence of…”
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Sibling pair linkage and association studies between bone mineral density and the insulin-like growth factor I gene locus by TAKACS, I, KOLLER, D. L, PEACOCK, M, CHRISTIAN, J. C, HUI, S. L, CONNEALLY, P. M, JOHNSTON, C. C, FOROUD, T, ECONS, M. J

“…A major determinant of the risk for osteoporosis in later life is bone mineral density (BMD) attained during early adulthood. BMD is a complex trait that…”
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