Search Results - "Eckley, D. M."

Dynactin Is Required for Microtubule Anchoring at Centrosomes by Quintyne, N. J., Gill, S. R., Eckley, D. M., Crego, C. L., Compton, D. A., Schroer, T. A.

“…The multiprotein complex, dynactin, is an integral part of the cytoplasmic dynein motor and is required for dynein-based motility in vitro and in vivo. In…”
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Cytoplasmic Dynein as a Facilitator of Nuclear Envelope Breakdown by Salina, Davide, Bodoor, Khaldon, Eckley, D.Mark, Schroer, Trina A., Rattner, J.B., Burke, Brian

“…During prophase in higher cells, centrosomes localize to deep invaginations in the nuclear envelope in a microtubule-dependent process. Loss of nuclear…”
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Molecular Analysis of the INCENPs (Inner Centromere Proteins): Separate Domains Are Required for Association with Microtubules during Interphase and with the Central Spindle during Anaphase by Mackay, Alastair M., Eckley, D. Mark, Chue, Calvin, Earnshaw, William C.

“…It has recently been proposed that mitotic chromosomes transport certain cytoskeletal proteins to the metaphase plate so that these proteins are able to…”
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Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End by Eckley, D. Mark, Gill, Steven R., Melkonian, Karin A., Bingham, James B., Goodson, Holly V., Heuser, John E., Schroer, Trina A.

“…The multisubunit protein, dynactin, is a critical component of the cytoplasmic dynein motor machinery. Dynactin contains two distinct structural domains: a…”
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A Dominant Mutant of Inner Centromere Protein (INCENP), a Chromosomal Protein, Disrupts Prometaphase Congression and Cytokinesis by Mackay, Alastair M., Ainsztein, Alexandra M., Eckley, D. Mark, Earnshaw, William C.

“…INCENP is a tightly bound chromosomal protein that transfers to the spindle midzone at the metaphase/anaphase transition. Here, we show that an INCENP…”
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Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells by Adams, R R, Eckley, D M, Vagnarelli, P, Wheatley, S P, Gerloff, D L, Mackay, A M, Svingen, P A, Kaufmann, S H, Earnshaw, W C

“…The inner centromere protein (INCENP), which has previously been described in chicken, frog and mouse, is required for correct chromosome segregation and…”
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Chromosomal Proteins and Cytokinesis: Patterns of Cleavage Furrow Formation and Inner Centromere Protein Positioning in Mitotic Heterokaryons and Mid-Anaphase Cells by Eckley, D. Mark, Ainsztein, Alexandra M., Mackay, Alastair M., Goldberg, Ilya G., Earnshaw, William C.

“…After the separation of sister chromatids in anaphase, it is essential that the cell position a cleavage furrow so that it partitions the chromatids into two…”
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Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals by Kazanis, Ilias, Lathia, Justin D, Vadakkan, Tegy J, Raborn, Eric, Wan, Ruiqian, Mughal, Mohamed R, Eckley, D Mark, Sasaki, Takako, Patton, Bruce, Mattson, Mark P, Hirschi, Karen K, Dickinson, Mary E, ffrench-Constant, Charles

“…The subependymal zone (SEZ) of the lateral ventricles is one of the areas of the adult brain where new neurons are continuously generated from neural stem…”
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Knee X-Ray Image Analysis Method for Automated Detection of Osteoarthritis by Shamir, Lior, Ling, Shari M., Scott, William W., Bos, Angelo, Orlov, Nikita, Macura, Tomasz J., Eckley, D. Mark, Ferrucci, Luigi, Goldberg, Ilya G.

“…We describe a method for automated detection of radiographic osteoarthritis (OA) in knee X-ray images. The detection is based on the Kellgren-Lawrence (KL)…”
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Nucleotide sequence of the mouse alpha 1-acid glycoprotein gene 1 by Cooper, R, Eckley, D M, Papaconstantinou, J

“…In a previous paper we presented evidence for the existence of at least two alpha 1-acid glycoprotein (AGP) genes in the mouse. One of the cDNA clones…”
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S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion by Warren, Cheryl D, Eckley, D Mark, Lee, Marina S, Hanna, Joseph S, Hughes, Adam, Peyser, Brian, Jie, Chunfa, Irizarry, Rafael, Spencer, Forrest A

“…Cohesion establishment and maintenance are carried out by proteins that modify the activity of Cohesin, an essential complex that holds sister chromatids…”
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Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1 by Eckley, D Mark, Schroer, Trina A

“…The dynein activator dynactin is a multiprotein complex with distinct microtubule- and cargo-binding domains. The cargo-binding domain contains a short,…”
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Nucleotide sequence of the mouse alpha sub(1)-acid glycoprotein gene 1 by Cooper, R, Eckley, D M, Papaconstantinou, J

“…In a previous paper the authors presented evidence for the existence of at least two alpha sub(1)-acid glycoprotein (AGP) genes in the mouse. One of the cDNA…”
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Nucleotide sequence of the mouse α1-acid glycoprotein gene 1 by COOPER, R, ECKLEY, D. M, PAPACONSTANTINOU, J

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