Search Results - "Eckhardt, Bruna V"
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CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
Published in Nucleic acids research (08-05-2023)“…Abstract During every cell cycle, both the genome and the associated chromatin must be accurately replicated. Chromatin Assembly Factor-1 (CAF-1) is a key…”
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Journal Article -
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Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF
Published in Science advances (29-07-2022)“…Nucleosome assembly requires the coordinated deposition of histone complexes H3-H4 and H2A-H2B to form a histone octamer on DNA. In the current paradigm,…”
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Journal Article