Search Results - "Eckerson, H W"

Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities by Gan, K N, Smolen, A, Eckerson, H W, La Du, B N

“…Evidence is presented that human serum contains a single enzyme with both paraoxonase and arylesterase activities. Throughout the steps of purification and…”
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Characteristics of the genetically determined allozymic forms of human serum paraoxonase/arylesterase by Smolen, A, Eckerson, H W, Gan, K N, Hailat, N, La Du, B N

“…Human serum paraoxonase/arylesterase is an esterase with broad substrate specificity. It occurs in two genetically determined allozymic forms, which we have…”
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The human serum paraoxonase/arylesterase polymorphism by Eckerson, H W, Wyte, C M, La Du, B N

“…The heterozygous human serum paraoxonase phenotype can be clearly distinguished from both homozygous phenotypes on the basis of its distinctive ratio of…”
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The human serum paraoxonase polymorphism: identification of phenotypes by their response to salts by Eckerson, H W, Romson, J, Wyte, C, La Du, B N

“…A method for identifying two human serum paraoxonase phenotypes in vitro has been developed based upon the effect of NaCl upon paraoxonase activity. In a…”
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Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase by Lockridge, O, Mottershaw-Jackson, N, Eckerson, H W, La Du, B N

“…The enzyme in human serum that rapidly hydrolyzes diacetylmorphine (heroin) to 6-acetylmorphine is identified in this report as serum cholinesterase (EC…”
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Multicenter reperfusion trial of intravenous anisoylated plasminogen streptokinase activator complex (APSAC) in acute myocardial infarction: Controlled comparison with intracoronary streptokinase by Anderson, Jeffrey L., Rothbard, Robert L., Hackworthy, Rosemary A., Sorensen, Sherman G., Fitzpatrick, Patricia G., Dahl, Charles F., Hagan, Arthur D., Browne, Kevin F., Symkoviak, Gary P., Menlove, Ronald L., Barry, William H., Eckerson, Harry W., Marder, Victor J.

“…The recent establishment of a firm therapeutic role for reperfusion in acute myocardial infarction has stimulated interest in the development of more ideal…”
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Multicenter patency trial of intravenous anistreplase compared with streptokinase in acute myocardial infarction by ANDERSON, J. L, SORENSEN, S. G, MORENO, F. L, HACHWORTHY, R. A, BROWNE, K. F, DALE, H. T, LEYA, F, DANGOISSE, V, ECKERSON, H. W, MARDER, V. J

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Paraoxon hydrolysis vs. covalent binding in the elimination of paraoxon in the rabbit by Butler, E G, Eckerson, H W, La Du, B N

“…Hydrolysis and covalent binding to nonessential esterases are two biochemical processes which can prevent paraoxon from reacting with the essential enzyme,…”
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A mathematical model for evaluating the reaction of paraoxon with human serum cholinesterase and with polymorphic forms of paraoxonase by Eckerson, H W, La Du, B N

“…The inhibition of cholinesterase of human serum by paraoxon can be predicted by a mathematical model which considers two competing reactions for paraoxon: one,…”
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Interchain disulfide bonds and subunit organization in human serum cholinesterase by Lockridge, O, Eckerson, H W, La Du, B N

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An improved method for phenotyping individuals for the human serum paraoxonase arylesterase polymorphism by La Du, B N, Piko, J I, Eckerson, H W, Vincent-Viry, M, Siest, G

“…Human serum paraoxonase/arylesterase is a polymorphic enzyme, determined by two allelic genes at one autosomal locus. These two isozymes are called (A) and…”
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Effect of entry exclusion on mating aggregates and transconjugants by Eckerson, H W, Reynard, A M

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The polymorphic paraoxonase/arylesterase isozymes of human serum by La Du, B N, Eckerson, H W

“…There is now considerable evidence that human serum contains an enzyme with both paraoxonase and arylesterase activities. The enzyme probably exists in two…”
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Multicenter patency trial of intravenous anistreplase compared with streptokinase in acute myocardial infarction. The TEAM-2 Study Investigators by Anderson, J L, Sorensen, S G, Moreno, F L, Hackworthy, R A, Browne, K F, Dale, H T, Leya, F, Dangoisse, V, Eckerson, H W, Marder, V J

“…Thrombolytic therapy has been shown to improve clinical outcome when administered early after the onset of symptoms of acute myocardial infarction; the…”
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Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies by Valentino, R J, Lockridge, O, Eckerson, H W, La Du, B N

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Immunological comparison of the usual and atypical human serum cholinesterase phenotypes by Eckerson, H W, Oseroff, A, Lockridge, O, La Du, B N

“…Antiserum prepared against highly purified usual human serum cholinesterase (the most common phenotype) cross-reacted identically with the atypical serum…”
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