Search Results - "Eckersley, Sonia"

Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies by Randall, Kevin, Henderson, Neil, Reens, Jaimini, Eckersley, Sonia, Nyström, Ann-Christin, South, Marie C, Balendran, Clare A, Böttcher, Gerhard, Hughes, Glen, Price, Sally A

“…Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the…”
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Identification of a Subset of Human Non-Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma by CUMBERBATCH, Marie, XIMING TANG, KIM, Edward S, XINYING SU, SHUQIONG FAN, GRAY, Neil, BLOWERS, David P, WISTUBA, Ignacio I, WOMACK, Chris, BERAN, Garry, ECKERSLEY, Sonia, XIN WANG, ELLSTON, Rebecca P. A, DEARDEN, Simon, COSULICH, Sabina, SMITH, Paul D, BEHRENS, Carmen

“…The phosphoinositide 3-kinase (PI3K) pathway is a major oncogenic signaling pathway and an attractive target for therapeutic intervention. Signaling through…”
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Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease by Gu, Gucci Jijuan, Wu, Di, Lund, Harald, Sunnemark, Dan, Kvist, Alexander J, Milner, Roy, Eckersley, Sonia, Nilsson, Lars N G, Agerman, Karin, Landegren, Ulf, Kamali-Moghaddam, Masood

“…The appearance of neurofibrillary tangles (NFT), one of the major hallmarks of Alzheimer's disease (AD), is most likely caused by inappropriate phosphorylation…”
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The Use of Antibodies in Small-Molecule Drug Discovery by Marsden, Catherine J, Eckersley, Sonia, Hebditch, Max, Kvist, Alexander J, Milner, Roy, Mitchell, Danielle, Warwicker, Juli, Marley, Anna E

“…Antibodies are powerful research tools that can be used in many areas of biology to probe, measure, and perturb various biological structures. Successful drug…”
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Validation of the BRCA1 antibody MS110 and the utility of BRCA1 as a patient selection biomarker in immunohistochemical analysis of breast and ovarian tumours by Milner, Roy, Wombwell, Helen, Eckersley, Sonia, Barnes, Donna, Warwicker, Juli, Van Dorp, Erica, Dearden, Simon, Hughes, Glen, Harbron, Chris, Wellings, Bob, Hodgson, Darren, Womack, Chris, Gray, Neil, Lau, Alan, O’Connor, Mark J., Marsden, Catherine, Kvist, Alexander J.

“…BRCA1 protein measurement has previously been evaluated as a potential diagnostic marker without reaching a conclusive recommendation. In this study, we…”
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Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα by Abbott, W Mark, Snow, Melanie, Eckersley, Sonia, Renshaw, Jonathan, Davies, Gareth, Norman, Richard A, Ceuppens, Peter, Slootstra, Jerry, Benschop, Joris J, Hamuro, Yoshitomo, Lee, Jessica E, Newham, Peter

“…TNFα (tumour necrosis factor α) is an early mediator in the systemic inflammatory response to infection and is therefore a therapeutic target in sepsis…”
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Erratum to: Validation of the BRCA1 antibody MS110 and the utility of BRCA1 as a patient selection biomarker in immunohistochemical analysis of breast and ovarian tumours by Milner, Roy, Wombwell, Helen, Eckersley, Sonia, Barnes, Donna, Warwicker, Juli, Van Dorp, Erica, Rowlinson, Rachel, Dearden, Simon, Hughes, Glen, Harbron, Chris, Wellings, Bob, Hodgson, Darren, Womack, Chris, Gray, Neil, Lau, Alan, O’Connor, Mark J., Marsden, Catherine, Kvist, Alexander J.

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