Search Results - "Eckerle, Isabella"
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Novel SARS-CoV-2 variants: the pandemics within the pandemic
Published in Clinical microbiology and infection (01-08-2021)“…Many new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the…”
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COVID-19 epidemic in Switzerland: on the importance of testing, contact tracing and isolation
Published in Swiss medical weekly (19-03-2020)“…Switzerland is among the countries with the highest number of coronavirus disease-2019 (COVID-19) cases per capita in the world. There are likely many people…”
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Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents
Published in Emerging infectious diseases (01-10-2020)“…Children do not seem to drive transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We isolated culture-competent virus in vitro from…”
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Definitions for coronavirus disease 2019 reinfection, relapse and PCR re-positivity
Published in Clinical microbiology and infection (01-03-2021)Get full text
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Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study
Published in The Lancet (British edition) (01-08-2020)“…Assessing the burden of COVID-19 on the basis of medically attended case numbers is suboptimal given its reliance on testing strategy, changing case…”
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Development and Validation of the Elecsys Anti-SARS-CoV-2 Immunoassay as a Highly Specific Tool for Determining Past Exposure to SARS-CoV-2
Published in Journal of clinical microbiology (22-09-2020)“…The Elecsys Anti-SARS-CoV-2 immunoassay (Roche Diagnostics) was developed to provide accurate, reliable detection of antibodies to severe acute respiratory…”
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Serologic vaccination response after solid organ transplantation: a systematic review
Published in PloS one (22-02-2013)“…Infectious diseases after solid organ transplantation (SOT) are one of the major complications in transplantation medicine. Vaccination-based prevention is…”
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Scientific consensus on the COVID-19 pandemic: we need to act now
Published in The Lancet (British edition) (31-10-2020)“…The infection fatality rate of COVID-19 is several-fold higher than that of seasonal influenza,2 and infection can lead to persisting illness, including in…”
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Antibody persistence in the first 6 months following SARS-CoV-2 infection among hospital workers: a prospective longitudinal study
Published in Clinical microbiology and infection (01-05-2021)“…To evaluate longitudinally the persistence of humoral immunity for up to 6 months in a cohort of hospital employees with mild coronavirus disease 2019…”
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Diagnostic accuracy of two commercial SARS-CoV-2 antigen-detecting rapid tests at the point of care in community-based testing centers
Published in PloS one (31-03-2021)“…Determine the diagnostic accuracy of two antigen-detecting rapid diagnostic tests (Ag-RDT) for SARS-CoV-2 at the point of care and define individuals'…”
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A high-throughput microfluidic nanoimmunoassay for detecting anti–SARS-CoV-2 antibodies in serum or ultralow-volume blood samples
Published in Proceedings of the National Academy of Sciences - PNAS (04-05-2021)“…Novel technologies are needed to facilitate large-scale detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific antibodies in human…”
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Neutralization capacity of antibodies elicited through homologous or heterologous infection or vaccination against SARS-CoV-2 VOCs
Published in Nature communications (04-07-2022)“…Emerging SARS-CoV-2 variants raise questions about escape from previous immunity. As the population immunity to SARS-CoV-2 has become more complex due to prior…”
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Validation and clinical evaluation of a SARS-CoV-2 surrogate virus neutralisation test (sVNT)
Published in Emerging microbes & infections (01-01-2020)“…To understand SARS-CoV-2 immunity after natural infection or vaccination, functional assays such as virus neutralising assays are needed. So far, assays to…”
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Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity
Published in Cell reports (Cambridge) (05-10-2021)“…SARS-CoV-2 infection in children is less severe than it is in adults. We perform a longitudinal analysis of the early innate responses in children and adults…”
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Sequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tract
Published in Emerging microbes & infections (01-12-2022)“…Although frequently reported since the beginning of the pandemic, questions remain regarding the impact of Severe Acute Respiratory Syndrome Coronavirus 2…”
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Link of a ubiquitous human coronavirus to dromedary camels
Published in Proceedings of the National Academy of Sciences - PNAS (30-08-2016)“…The four human coronaviruses (HCoVs) are globally endemic respiratory pathogens. The Middle East respiratory syndrome (MERS) coronavirus (CoV) is an emerging…”
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Persistence of anti-SARS-CoV-2 antibodies: immunoassay heterogeneity and implications for serosurveillance
Published in Clinical microbiology and infection (01-11-2021)“…Serological studies have been critical in tracking the evolution of the COVID-19 pandemic. Data on anti-SARS-CoV-2 antibodies persistence remain sparse,…”
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Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination
Published in Emerging infectious diseases (01-08-2020)“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) created an exceptional situation in which numerous laboratories in Europe…”
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A SARS-CoV-2 omicron (B.1.1.529) variant outbreak in a primary school in Geneva, Switzerland
Published in The Lancet infectious diseases (01-06-2022)“…Cumulative infection incidence was four (33%) of 12 children in class A (which increased to five [42%] of 12 if including a probable case, as defined in the…”
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Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroconversion and occupational exposure of employees at a Swiss university hospital: A large longitudinal cohort study
Published in Infection control and hospital epidemiology (01-03-2022)“…The dynamics of coronavirus disease 2019 (COVID-19) seroconversion of hospital employees are understudied. We measured the proportion of seroconverted…”
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