Search Results - "Ecker, Rupert C."
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Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer
Published in Current treatment options in oncology (01-10-2023)“…Opinion statement Prostate cancer (PCa) is the second most diagnosed malignant neoplasm and is one of the leading causes of cancer-related death in men…”
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AC-265347 Inhibits Neuroblastoma Tumor Growth by Induction of Differentiation without Causing Hypocalcemia
Published in International journal of molecular sciences (13-04-2022)“…Neuroblastoma is the most common extracranial solid tumor of childhood, with heterogeneous clinical manifestations ranging from spontaneous regression to…”
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Microscopy‐based multicolor tissue cytometry at the single‐cell level
Published in Cytometry. Part A (01-06-2004)“…Cytomics is a novel perspective from which to look at life. As with genomics and proteomics before, this discipline requires novel and innovative techniques…”
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Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β
Published in Clinical cancer research (01-07-2011)“…In glioma-in contrast to various other cancers-the impact of T-lymphocytes on clinical outcome is not clear. We investigated the clinical relevance and…”
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Clinical and cytological effects of pimecrolimus cream 1% after resolution of active atopic dermatitis lesions by topical corticosteroids: a randomized controlled trial
Published in Dermatology (Basel) (01-02-2011)“…Topical pimecrolimus may maintain remissions of atopic dermatitis (AD) by inhibiting subclinical inflammation. To evaluate clinical and cytological effects of…”
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Next-Generation Digital Histopathology of the Tumor Microenvironment
Published in Genes (07-04-2021)“…Progress in cancer research is substantially dependent on innovative technologies that permit a concerted analysis of the tumor microenvironment and the…”
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Application of spectral imaging microscopy in cytomics and fluorescence resonance energy transfer (FRET) analysis
Published in Cytometry. Part A (01-06-2004)“…Background Specific signal detection has been a fundamental issue in fluorescence microscopy. In the context of tissue samples, this problem has been even more…”
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Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer
Published in Leukemia (01-11-2022)“…The composition of the gut microbiome influences the clinical course after allogeneic hematopoietic stem cell transplantation (HSCT), but little is known about…”
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Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer
Published in Leukemia (01-03-2023)Get full text
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An improved method for discrimination of cell populations in tissue sections using microscopy‐based multicolor tissue cytometry
Published in Cytometry. Part A (01-03-2006)“…Background: In tissue context, researchers and pathologists lack a generally applicable standard for quantitative determination of cytological parameters…”
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Cytomics goes 3D: Toward tissomics
Published in Cytometry. Part A (01-05-2005)Get full text
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Cytokine Expression Pattern in Benign Prostatic Hyperplasia Infiltrating T Cells and Impact of Lymphocytic Infiltration on Cytokine mRNA Profile in Prostatic Tissue
Published in Laboratory investigation (01-08-2003)“…The aim of the study is to characterize the type of immune response in benign prostatic hyperplasia (BPH) tissue. BPH tissue–derived T cells (n = 10) were…”
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Monocytes/macrophages in kidney allograft intimal arteritis: no association with markers of humoral rejection or with inferior outcome
Published in Nephrology, dialysis, transplantation (01-06-2009)“…Background. Several studies indicate that interstitial and intracapillary monocytes/macrophages (MO) represent a significant proportion of graft-infiltrating…”
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A functional chimaeric S-layer-enhanced green fluorescent protein to follow the uptake of S-layer-coated liposomes into eukaryotic cells
Published in Biochemical journal (15-04-2004)“…The chimaeric gene encoding a C-terminally truncated form of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 and the EGFP (enhanced green fluorescent…”
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3D parallel coordinate systems—A new data visualization method in the context of microscopy‐based multicolor tissue cytometry
Published in Cytometry. Part A (01-07-2006)“…Background: Presentation of multiple interactions is of vital importance in the new field of cytomics. Quantitative analysis of multi‐ and polychromatic…”
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Inhibition of restenosis by tissue factor pathway inhibitor: in vivo and in vitro evidence for suppressed monocyte chemoattraction and reduced gelatinolytic activity
Published in Blood (01-03-2004)“…Activation of inflammatory and procoagulant mechanisms is thought to contribute significantly to the initiation of restenosis, a common complication after…”
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Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia
Published in Blood (06-07-2023)“…•KDM1A activation marks high-risk CLL, and genetic KDM1A depletion impedes leukemic growth via cell-intrinsic and milieu-derived programs.•KDM1A loss alters H3…”
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