Search Results - "Eckels, David"

Immunologic effects of continuous-flow left ventricular assist devices before and after heart transplant by Ko, Byung-Soo, Drakos, Stavros, Kfoury, Abdallah G, Hurst, Denise, Stoddard, Gregory J, Willis, Carrie A, Delgado, Julio C, Hammond, Elizabeth H, Gilbert, Edward M, Alharethi, Rami, Revelo, Monica P, Nativi-Nicolau, Jose, Reid, Bruce B, McKellar, Stephen H, Wever-Pinzon, Omar, Miller, Dylan V, Eckels, David D, Fang, James C, Selzman, Craig H, Stehlik, Josef

“…Background Immune allosensitization can be triggered by continuous-flow left ventricular assist devices (CF LVAD). However, the effect of this type of…”
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Accelerating Evidence Synthesis in Observational Studies: Development of a Living Natural Language Processing-Assisted Intelligent Systematic Literature Review System by Manion, Frank J, Du, Jingcheng, Wang, Dong, He, Long, Lin, Bin, Wang, Jingqi, Wang, Siwei, Eckels, David, Cervenka, Jan, Fiduccia, Peter C, Cossrow, Nicole, Yao, Lixia

“…Systematic literature review (SLR), a robust method to identify and summarize evidence from published sources, is considered to be a complex, time-consuming,…”
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In Vitro Responses to Avian Influenza H5 by Human CD4 T Cells by Cusick, Matthew F, Wang, Shuping, Eckels, David D

“…To address the question of whether human T cells are capable of recognizing novel isolates of influenza virus, in vitro responses to recombinant Ags and…”
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Utility of Virtual Crossmatch in Sensitized Patients Awaiting Heart Transplantation by Stehlik, Josef, MD, MPH, Islam, Nauman, MD, Hurst, Denise, Kfoury, Abdallah G., MD, Movsesian, Matthew A., MD, Fuller, Ann, Delgado, Julio C., MD, Hammond, M. Elizabeth H., MD, Gilbert, Edward M., MD, Renlund, Dale G., MD, Bader, Feras, MD, Fisher, Patrick W., MD, PhD, Bull, David A., MD, Singhal, Arun K., MD, PhD, Eckels, David D., PhD

“…Background Organ transplant candidates with serum antibodies directed against human leukocyte antigens (HLA) face longer waiting times and higher mortality…”
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Prior Human Leukocyte Antigen-Allosensitization and Left Ventricular Assist Device Type Affect Degree of Post-implantation Human Leukocyte Antigen-Allosensitization by Drakos, Stavros G., MD, Kfoury, Abdallah G., MD, Kotter, John R., MD, Reid, Bruce B., MD, Clayson, Stephen E., MD, Selzman, Craig H., MD, Stehlik, Josef, MD, Fisher, Patrick W., DO, PhD, Merida, Mario, MS, Eckels, David D., MD, Brunisholz, Kim, BS, Horne, Benjamin D., PhD, Stoker, Sandi, RN, BSN, Li, Dean Y., MD, PhD, Renlund, Dale G., MD

“…Left ventricular assist device (LVAD) implantation before heart transplantation has been associated with formation of antibodies directed against human…”
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The detection and role of circulating antibodies in rejection by Eckels, David D., Stehlik, Josef, Kfoury, Abdallah G.

“…In this review, we first discuss the evolution and current controversies in antibody detection methodology for transplant candidates. Then, we summarize how…”
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Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen by Cusick, Matthew F, Libbey, Jane E, Trede, Nikolaus S, Eckels, David D, Fujinami, Robert S

“…Abstract Immune-mediated diseases [multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE)] are driven by proliferating, highly activated…”
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The impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation by Bull, David A., MD, Reid, Bruce B., MD, Selzman, Craig H., MD, Mesley, Rebecca, BS, Drakos, Stavros, MD, Clayson, Steven, MD, Stoddard, Greg, PhD, Gilbert, Edward, MD, Stehlik, Josef, MD, Bader, Feras, MD, Kfoury, Abdallah, MD, Budge, Deborah, MD, Eckels, David D., PhD, Fuller, Anne, BS, Renlund, Dale, MD, Patel, Amit N., MD

“…Objective To determine the impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation. Methods From January 1,…”
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Naturally occurring CD4+ T-cell epitope variants act as altered peptide ligands leading to impaired helper T-cell responses in hepatitis C virus infection by Cusick, Matthew F, Yang, Meiying, Gill, Joan C, Eckels, David D

“…Abstract Hepatitis C virus (HCV) has a high rate of replication and lacks RNA-proofreading capabilities, thereby leading to variant or mutant viruses…”
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Hepatitis C Virus Induces Regulatory T Cells by Naturally Occurring Viral Variants to Suppress T Cell Responses by Cusick, Matthew F., Schiller, Jennifer J., Gill, Joan C., Eckels, David D.

“…Regulatory T cell markers are increased in chronically infected individuals with the hepatitis C virus (HCV), but to date, the induction and maintenance of…”
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25-P HLA antibodies that are not detected by the C1q screen TM can fix complement and are clinically significant by Fuller, Anne, Williams, Kevin, Hurst, Denise, Ellinger, Lori, Eckels, David D

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Donor-reactive HLA antibodies in renal allograft recipients: Considerations, complications, and conundrums by Gebel, Howard M, Moussa, Omar, Eckels, David D, Bray, Robert A

“…Abstract Whether sensitized patients wait for a compatible crossmatch with a deceased donor, enter a paired exchange program with the hope of finding a…”
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Penaeus monodon tropomyosin induces CD4 T-cell proliferation in shrimp-allergic patients by Wang, Shuping, Delgado, Julio C, Ravkov, Eugene, Eckels, David D, Georgelas, Ann, Pavlov, Igor Y, Cusick, Matthew, Sebastian, Kate, Gleich, Gerald J, Wagner, Lori A

“…Abstract Shellfish allergy affects approximately 2% of the population and can cause immediate hypersensitivity reactions such as urticaria, swelling,…”
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Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity by Wang, Shuping, Buchli, Rico, Schiller, Jennifer, Gao, Jianen, VanGundy, Rodney S, Hildebrand, William H, Eckels, David D

“…AIM:To understand how interactions between hepatitis C virus(HCV) and the host's immune system might lead to viral persistence or effective elimination of…”
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Positive B-cell only flow cytometric crossmatch: Implications for renal transplantation by Delgado, Julio C., Eckels, David D.

“…In renal transplantation, the presence of anti-donor HLA antibodies is associated with early rejection and accelerated graft loss. The clinical relevance of…”
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No occurrence of de novo HLA antibodies in patients with early corticosteroid withdrawal in a 5-year prospective randomized study by Delgado, Julio C, Fuller, Anne, Ozawa, Miyuki, Smith, Lonnie, Terasaki, Paul I, Shihab, Fuad S, Eckels, David D

“…The purpose of this study was to determine the effect of early corticosteroid cessation on the occurrence of de novo human leukocyte antigen (HLA) antibody…”
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Mutations in Immunodominant T Cell Epitopes Derived from the Nonstructural 3 Protein of Hepatitis C Virus Have the Potential for Generating Escape Variants That May Have Important Consequences for T Cell Recognition by Wang, Huiru, Eckels, David D

“…One of the most disturbing features of hepatitis C virus (HCV) is its long-term persistence in the host. One hypothesis to explain this phenomenon is that HCV…”
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16-P: Complement-mediated inhibition of solid-phase antibody detection (SPAD) by Fuller, Anne, Williams, Kevin, Hurst, Denise, Konnick, Ketra, Eckels, David D

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Modulation of the peripheral T-Cell response by CD4 mutants of hepatitis C virus: transition from a Th1 to a Th2 response by Wang, Jane H, Layden, Thomas J, Eckels, David D

“…A disturbing feature of hepatitis C virus (HCV) is its long-term persistence in roughly 85% of those infected. Escape mutants may play a major role in HCV…”
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37-P: In silico vXM compared to FCXM in deceased donor kidney transplants by Lai, Jennifer, Eckels, David D, Gebel, Howard M, Bray, Robert A, Patel, Parul, Katznelson, Steven, Peddi, V. Ram, Osorio, Robert, Bry, William

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