Search Results - "Echeverria, Pablo"

Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study by Kett, Daniel H, Azoulay, Elie, Echeverria, Pablo M, Vincent, Jean-Louis

“…OBJECTIVES:To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients…”
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The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation by Bhattacharya, Kaushik, Weidenauer, Lorenz, Luengo, Tania Morán, Pieters, Ellis C., Echeverría, Pablo C., Bernasconi, Lilia, Wider, Diana, Sadian, Yashar, Koopman, Margreet B., Villemin, Matthieu, Bauer, Christoph, Rüdiger, Stefan G. D., Quadroni, Manfredo, Picard, Didier

“…Hop/Stip1/Sti1 is thought to be essential as a co-chaperone to facilitate substrate transfer between the Hsp70 and Hsp90 molecular chaperones. Despite this…”
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The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity by Echeverria, Pablo C, Bhattacharya, Kaushik, Joshi, Abhinav, Wang, Tai, Picard, Didier

“…The molecular chaperone Hsp90 is an essential and highly abundant central node in the interactome of eukaryotic cells. Many of its large number of client…”
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Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility by Echeverria, Pablo C., Picard, Didier

“…Steroid hormone receptors (SHRs) are notorious intracellular travellers, transiting among different cellular compartments as they mature, are subjected to…”
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Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins by Mazaira, Gisela I, Echeverria, Pablo C, Galigniana, Mario D

“…It has been demonstrated that tetratricopeptide-repeat (TPR) domain proteins regulate the subcellular localization of glucocorticoid receptor (GR). This study…”
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Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling by Segala, Gregory, Bennesch, Marcela A., Ghahhari, Nastaran Mohammadi, Pandey, Deo Prakash, Echeverria, Pablo C., Karch, François, Maeda, Robert K., Picard, Didier

“…In response to extracellular signals, many signalling proteins associated with the plasma membrane are sorted into endosomes. This involves endosomal fusion,…”
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Progesterone/RANKL is a major regulatory axis in the human breast by Tanos, Tamara, Sflomos, George, Echeverria, Pablo C, Ayyanan, Ayyakkannu, Gutierrez, Maria, Delaloye, Jean-Francois, Raffoul, Wassim, Fiche, Maryse, Dougall, William, Schneider, Pascal, Yalcin-Ozuysal, Ozden, Brisken, Cathrin

“…Estrogens and progesterones are major drivers of breast development but also promote carcinogenesis in this organ. Yet, their respective roles and the…”
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The Hegemonic Character of Techno-Functional Neo-Immanentism and Its Relationship with Culture Wars by Sánchez Capdequí, Celso, Gil-Gimeno, Javier, Echeverría Esparza, Pablo

“…This paper analyzes the social processes that have led to the consolidation of a technocratic secular order and the type of cultural struggle that has made…”
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Drosophila melanogaster as a model organism for screening acetylcholinesterase reactivators by Macedo, Pablo Echeverria, Batista, Jéssica Eduarda Santos, Souza, Lorena Raspanti, Dafre, Alcir Luiz, Farina, Marcelo, Kuca, Kamil, Posser, Thais, Pinto, Paulo Marcos, Boldo, Juliano Tomazzoni, Franco, Jeferson Luis

“…The widely used insecticide chlorpyrifos (CP) is known to inhibit acetylcholinesterase (AChE) activity attributed to result in various neurological disorders…”
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Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy by Fierro-Monti, Ivo, Echeverria, Pablo, Racle, Julien, Hernandez, Celine, Picard, Didier, Quadroni, Manfredo

“…The molecular chaperone Hsp90-dependent proteome represents a complex protein network of critical biological and medical relevance. Known to associate with…”
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Protozoan HSP90-heterocomplex: molecular interaction network and biological significance by Figueras, Maria J, Echeverria, Pablo C, Angel, Sergio O

“…The HSP90 chaperone is a highly conserved protein from bacteria to higher eukaryotes. In eukaryotes, this chaperone participates in different large complexes,…”
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RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes by Recouvreux, María Sol, Grasso, Esteban Nicolás, Echeverria, Pablo Christian, Rocha-Viegas, Luciana, Castilla, Lucio Hernán, Schere-Levy, Carolina, Tocci, Johanna Melisa, Kordon, Edith Claudia, Rubinstein, Natalia

“…Runx1 participation in epithelial mammary cells is still under review. Emerging data indicates that Runx1 could be relevant for breast tumor promotion…”
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An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine by Echeverría, Pablo C, Bernthaler, Andreas, Dupuis, Pierre, Mayer, Bernd, Picard, Didier

“…Understanding the functions of proteins requires information about their protein-protein interactions (PPI). The collective effort of the scientific community…”
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Toxoplasma gondii Hsp90: potential roles in essential cellular processes of the parasite by Angel, Sergio O, Figueras, Maria J, Alomar, Maria L, Echeverria, Pablo C, Deng, Bin

“…Hsp90 is a widely distributed and highly conserved molecular chaperone that is ubiquitously expressed throughout nature, being one of the most abundant…”
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A review of recent patents on the protozoan parasite HSP90 as a drug target by Angel, Sergio O, Matrajt, Mariana, Echeverria, Pablo C

“…Diseases caused by protozoan parasites are still an important health problem. These parasites can cause a wide spectrum of diseases, some of which are severe…”
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Candida prophylaxis and therapy in the ICU by Echeverria, Pablo M, Kett, Daniel H, Azoulay, Elie

“…The incidence of invasive candidiasis in critically ill patients has increased over the past decade and is associated with considerable morbidity and…”
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Toxoplasma gondii Hsp90 is a Potential Drug Target Whose Expression and Subcellular Localization are Developmentally Regulated by Echeverria, Pablo C., Matrajt, Mariana, Harb, Omar S., Zappia, María P., Costas, Monica A., Roos, David S., Dubremetz, Jean François, Angel, Sergio O.

“…Two replicative forms characterize the asexual cycle of the protozoan parasite Toxoplasma gondii: rapidly growing tachyzoites and slowly dividing encysted…”
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The Hsp90 co-chaperone p23 of Toxoplasma gondii: Identification, functional analysis and dynamic interactome determination by Echeverria, Pablo C., Figueras, Maria J., Vogler, Malvina, Kriehuber, Thomas, de Miguel, Natalia, Deng, Bin, Dalmasso, Maria C., Matthews, Dwight E., Matrajt, Mariana, Haslbeck, Martin, Buchner, Johannes, Angel, Sergio O.

“…Toxoplasma Hsp90 co-chaperone p23 translocates to the parasite nucleus in the bradyzoite stage. A proteomic snapshot of Toxoplasma p23 and Hsp90 interactomes…”
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The removal of arsenic and metals from highly acidic water in horizontal subsurface flow constructed wetlands with alternative supporting media by Lizama-Allende, Katherine, Ayala, José, Jaque, Ignacio, Echeverría, Pablo

“…A laboratory-scale horizontal subsurface flow constructed wetland system was used to quantify the arsenic removal capacity in the treatment of highly acidic,…”
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Recombinant GRA4 or ROP2 protein combined with alum or the gra4 gene provides partial protection in chronic murine models of toxoplasmosis by Martin, Valentina, Supanitsky, Alicia, Echeverria, Pablo C, Litwin, Silvana, Tanos, Tamara, De Roodt, Adolfo R, Guarnera, Eduardo A, Angel, Sergio O

“…The efficacy of vaccination with Toxoplasma gondii recombinant GRA4 (rGRA4) and ROP2 (rRPO2) proteins and a mix of both combined with alum were evaluated in…”
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