Search Results - "Echeverría, Gustavo"

Enol-imino–Keto-enamine Tautomerism in a Diazepine Derivative: How Decisive Are the Intermolecular Interactions in the Equilibrium? by Rocha, Mariana, Gil, Diego M, Echeverría, Gustavo A, Piro, Oscar E, Jios, Jorge L, Ulic, Sonia E

“…The strange tautomeric equilibrium behavior exhibited by a new o-hydroxyphenyl diazepine derivative when the compound is analyzed both in solution and solid…”
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Promising Dual Anticancer and Antimetastatic Action by a Cu(II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models by Santa Maria de la Parra, Lucía, Romo, Adolfo I. B., Rodríguez-López, Joaquín, Nascimento, Otaciro R., Echeverría, Gustavo A., Piro, Oscar E., León, Ignacio E.

“…Osteosarcoma cancers are becoming more common in children and young adults, and existing treatments have low efficacy and a very high mortality rate, making it…”
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Tautomerism and Rotamerism of Favipiravir and Halogenated Analogues in Solution and in the Solid State by Romero, Angel H., Fuentes, Germán, Suescun, Leopoldo, Piro, Oscar, Echeverría, Gustavo, Gotopo, Lourdes, Pezaroglo, Horacio, Álvarez, Guzmán, Cabrera, Gustavo, Cerecetto, Hugo, Couto, Marcos

“…Favipiravir is an important selective antiviral against RNA-based viruses, and currently, it is being repurposed as a potential drug for the treatment of…”
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Anticancer activity of a new copper(II) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies on 2D and 3D breast cancer cell models by Balsa, Lucia M, Ferraresi-Curotto, Verónica, Lavecchia, Martin J, Echeverría, Gustavo A, Piro, Oscar E, García-Tojal, Javier, Pis-Diez, Reinaldo, González-Baró, Ana C, León, Ignacio E

“…We report here the synthesis, crystal structure, characterization and anticancer activity of a copper(ii)-hydrazone complex, [Cu(MeBHoVa)(H2O)2](NO3) (for…”
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Pre-existing T-cell immunity to SARS-CoV-2 in unexposed healthy controls in Ecuador, as detected with a COVID-19 Interferon-Gamma Release Assay by Echeverría, Gustavo, Guevara, Ángel, Coloma, Josefina, Ruiz, Alison Mera, Vasquez, María Mercedes, Tejera, Eduardo, de Waard, Jacobus H.

“…•We used an IGRA to analyze a T-cell response in COVID-19 patients and healthy unexposed controls.•We show that 80% of the convalescent COVID-19 patients had…”
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Multifunctional organometallic compounds for the treatment of Chagas disease: Re(I) tricarbonyl compounds with two different bioactive ligands by Soba, Mariano, Scalese, Gonzalo, Casuriaga, Federico, Pérez, Nicolás, Veiga, Nicolás, Echeverría, Gustavo A, Piro, Oscar E, Faccio, Ricardo, Pérez-Díaz, Leticia, Gasser, Gilles, Machado, Ignacio, Gambino, Dinorah

“…Chagas' disease (American Trypanosomiasis) is an ancient and endemic illness in Latin America caused by the protozoan parasite Although there is an urgent need…”
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Spontaneous resolution of diastereomeric glycosyl isoxazolines: A combined theoretical and experimental study in solution and in the crystalline form by Barri, Ivan A., Riafrecha, Leonardo E., Echeverría, Gustavo A., Piro, Oscar E., Colinas, Pedro A.

“…•A galactosyl isoxazoline has been prepared by phenyl nitrile oxide cycloaddition.•The two diastereomeric isoxazolines have been spontaneously resolved by…”
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Synthesis and structural characterization of poly-thiolactones with varied ring sizes and endocyclic functional groups by Espinosa, Zuly Y. Delgado, Echeverría, Gustavo A., Piro, Oscar E., Erben, Mauricio F.

“…•Novel poly-thiolactone synthesis with endocyclic ether, polyether, and lactone groups.•Controlled thioester bond formation using diacyl chlorides and…”
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Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis by Echeverría, Gustavo, Zumárraga, Martín J., Proaño-Pérez, Freddy, Blasco, Francisco Barceló, de Waard, Jacobus H.

“…Although several brands of tuberculin purified protein derivatives (PPDs) are available for diagnosing bovine tuberculosis (bTB), comparative studies to…”
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Role of fluorine-fluorine and weak intermolecular interactions in the supramolecular network of a new trifluoromethyl-1,5-benzodiazepine: Crystal structure, Hirshfeld surface analysis and theoretical study by Rocha, Mariana, Echeverría, Gustavo A., Piro, Oscar E., Jios, Jorge L., Ulic, Sonia E., Gil, Diego M.

“…[Display omitted] •The role of F⋯F interactions has been evaluated experimental and theoretically.•Two tautomeric forms (enol-imino and keto-enamine) of BDZP…”
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A novel Co(II) complex with sulfamethoxazole ligand: Isostructuralism, non-covalent interactions, Hirshfeld surfaces, crystal voids and energy calculations by Santo, Alejandro Di, Pérez, Hiram, Echeverría, Gustavo A., Piro, Oscar E., Frontera, Antonio, Gil, Diego M.

“…•A new Co(II) complex with sulfamethoxazole as ligand has been synthesized and characterized.•The crystal structure has been solved by X-ray diffraction…”
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Unravelling the importance of hydrogen bonds and dihydrogen interactions in the supramolecular assembly of a caryolan-1-ol derivative: an experimental and theoretical investigation by Muro, Ana Carolina, Maturano, Lourdes Valeria, Echeverría, Gustavo A., Piro, Oscar E., Catalán, César A.N., Gil, Diego M.

“…•A caryolan-1-ol derivative (3) has been synthesized and characterized.•The crystal structure of 3 has been solved by single-crystal X-ray diffraction…”
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Crystal engineering with novel antipyrine derivatives: Insights from X-ray diffraction, Hirshfeld surface analysis, and DFT calculations on intermolecular interactions by Rocha, Mariana, Saeed, Aamer, Gil, Diego M., Echeverría, Gustavo A., Piro, Oscar E., Khurshid, Asma, Arshad, Muhammad, Shah, Syed Adnan Ali, Erben, Mauricio Federico

“…•Synthesis of three novel antipyrine-amide derivatives confirmed by spectroscopic analysis.•Molecular and crystal structures for the three compounds were…”
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Exploring weak intermolecular interactions in thiocyanate-bonded Zn(ii) and Cd(ii) complexes with methylimidazole: crystal structures, Hirshfeld surface analysis and luminescence properties by Di Santo, Alejandro, Pérez, Hiram, Echeverría, Gustavo A, Piro, Oscar E, Iglesias, Rodrigo A, Carbonio, Raúl E, Ben Altabef, Aida, Gil, Diego M

“…Four new thiocyanate-Zn(ii) and -Cd(ii) complexes with 1-methylimidazole (1-MeIm) and 2-methylimidazole (2-MeIm), namely, Zn(1-MeIm) (SCN) (1), Zn(2-MeIm)…”
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Ternary copper(II) complex of 5-hydroxytryptophan and 1,10-phenanthroline with several pharmacological properties and an adequate safety profile by Naso, Luciana G., Martínez Medina, Juan J., D'Alessandro, Franco, Rey, Marilin, Rizzi, Alberto, Piro, Oscar E., Echeverría, Gustavo A., Ferrer, Evelina G., Williams, Patricia A.M.

“…We report the synthesis and biological evaluation of a ternary copper complex, [Cu(5HTP)(phen)(H2O)](NO3).2H2O, with the antioxidant agent 5-hydroxytryptophan…”
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Crystal structure and infrared and Raman spectra of K3[Cr(CN)5NO].2H2O, a member of an iconic family of complexes in coordination chemistry by Piro, Oscar E., Echeverría, Gustavo A., Navaza, Alda, Güida, Jorge A.

“…[Display omitted] •Accurate metrics of [CrI(CN)5NO]3- complex in its dihydrate potassium salt.•Advanced X-ray data collection and space group and structure…”
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Molecular recognition of halogen-bond of Diiodine with an Ambidentate ligand: Fluorometry as lead strategy for analysis in solution by Gotopo, Lourdes A., Güida, Jorge A., Echeverría, Gustavo, Piro, Oscar E., Romero, Ivan E., Castelli, Romina, Cabrera, Gustavo, Cabral, Pablo, Cerecetto, Hugo E., Romero, Angel H.

“…•Exact chemical connectivity of the halogen bond for an ambidentate ligand in solution and solid state.•Fluorometry as lead strategy for elucidation for…”
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Glucoimines incorporating classical and non-classical carbonic anhydrase pharmacophores: Design, synthesis, conformational analysis, biological evaluation, and docking simulations by Vásquez, Ivana R., Riafrecha, Leonardo E., Martínez Heredia, Leandro, Echeverría, Gustavo A., Piro, Oscar E., Lavecchia, Martín J., Supuran, Claudiu T., Colinas, Pedro A.

“…•Glucoimines incorporating classical and non-classical CA pharmacophores are described.•Conformational behavior of glucoimines has been studied in solution and…”
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Novel synthesis and crystallographic results of zinc substituted hydroxyapatite with high thermal stability by Guerra-López, José R., Bianchi, Ana E., Ramos, Marcelo A., Ferraresi-Curotto, Verónica, Güida, Jorge A., Echeverría, Gustavo A.

“…Hydroxyapatite (CaHap) doped with different amounts of Zn(II) has been studied by complementary techniques, X-ray powder diffraction (XRPD), thermogravimetry…”
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Lamotriginium crotonate and lamotriginium salicylate ethanol monosolvate: the role of solvent molecules in the packing organization by Freire, Eleonora, Echeverría, Gustavo A., Baggio, Ricardo

“…Two lamotriginium salts, namely lamotriginium crotonate [systematic name: 3,5‐diamino‐6‐(2,3‐dichlorophenyl)‐1,2,4‐triazin‐2‐ium but‐2‐enoate,…”
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