Search Results - "Ebube, Nkere K."

Sustained release of acetaminophen from a heterogeneous mixture of two hydrophilic non-ionic cellulose ether polymers by Ebube, Nkere K., Jones, Alan B.

“…This study examined the release of acetaminophen (APAP) from hydroxypropyl methylcellulose (HPMC) and hydroxypropyl cellulose (HPC) matrices. The effect of…”
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A Comparison of Reflectance and Transmittance Near-Infrared Spectroscopic Techniques in Determining Drug Content in Intact Tablets by Thosar, Shilpa S., Forbess, Reba A., Ebube, Nkere K., Chen, Yixin, Rubinovitz, Ronald L., Kemper, Mark S., Reier, George E., Wheatley, Thomas A., Shukla, Atul J.

“…Drug contents of intact tablets were determined using non-destructive near infrared (NIR) reflectance and transmittance spectroscopic techniques. Tablets were…”
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Preformulation studies and characterization of the physicochemical properties of amorphous polymers using artificial neural networks by Ebube, Nkere K., Owusu-Ababio, Godfried, Adeyeye, Christiana Moji

“…The utility of artificial neural networks (ANNs) as a preformulation tool to determine the physicochemical properties of amorphous polymers such as the…”
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Sustained Release of Acetaminophen from Heterogeneous Matrix Tablets: Influence of Polymer Ratio, Polymer Loading, and Co-active on Drug Release by Ebube, Nkere K., Hikal, Ahmed H., Wyandt, Christy M., Beer, Don C., Miller, Larry G., Jones, Alan B.

“…ABSTRACT The aim of this research was to investigate the effect of pseudoephedrine (PE), polymer ratio, and polymer loading on the release of acetaminophen…”
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Effect of drug, formulation and process variables on granulation and compaction characteristics of heterogeneous matrices. Part 1: HPMC and HPC systems by Ebube, Nkere K, Hikal, Ahmed H, Wyandt, Christy M, Beer, Don C, Miller, Larry G, Jones, Alan B

“…The purpose of this study was to investigate the effects of hydroxypropyl methylcellulose (HPMC) and hydroxypropyl cellulose (HPC) ratios, total polymer…”
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Preformulation Studies and Characterization of Proposed Chondroprotective Agents: Glucosamine HCl and Chondroitin Sulfate by Ebube, Nkere K., Mark, William, Hahm, Huijeong

“…Purpose: Glucosamine HCl and chondroitin sulfate are proposed chondroprotective agents commonly used as dietary supplements. This study examined the…”
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Controlled Release Tacrine Delivery System for the Treatment of Alzheimer's Disease by Qing Yang, Douglas Williams, Godfried Owusu-Ababio, Nkere K. Ebube, Muhammad J. Habib

“…Alzheimer's disease is a neurodegenerative condition that affects ~5 million people and is the fourth leading cause of death in America. Tacrine is one of the…”
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Comparative Dissolution Studies for Mefenamic Acid-Polyethylene Glycol Solid Dispersion Systems and Tablets by Owusu-Ababio, Godfried, Ebube, Nkere K., Reams, Renee, Habib, Muhammad

“…ABSTRACT The purpose of this study was to enhance the dissolution of mefenamic acid (MFA) through the formation of solid dispersion systems, and to compare the…”
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Relating Formulation Variables to in Vitro Dissolution Using an Artificial Neural Network by Ebube, Nkere K., McCall, Troy, Chen, Yixin, Meyer, Marvin C.

“…ABSTRACT The purpose of this paper was to investigate the effect of several experimental variables on the ability of a neural network to predict in vitro…”
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