Search Results - "Ebert, Matthias P A"

Performance of epigenetic markers SEPT9 and ALX4 in plasma for detection of colorectal precancerous lesions by Tänzer, Marc, Balluff, Benjamin, Distler, Jürgen, Hale, Kari, Leodolter, Andreas, Röcken, Christoph, Molnar, Bela, Schmid, Roland, Lofton-Day, Catherine, Schuster, Tibor, Ebert, Matthias P A

“…Screening for colorectal cancer (CRC) has shown to reduce cancer-related mortality, however, acceptance and compliance to current programmes are poor…”
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Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ by Yu, Yanxiong, Farooq, Mohammad S., Eberhart Meessen, Sabine, Jiang, Yidan, Kato, Dominik, Zhan, Tianzuo, Weiss, Christel, Seger, Rony, Kang, Wei, Zhang, Xiang, Yu, Jun, Ebert, Matthias P. A., Burgermeister, Elke

“…Manipulation of the subcellular localization of transcription factors by preventing their shuttling via the nuclear pore complex (NPC) emerges as a novel…”
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TFAP2E–DKK4 and Chemoresistance in Colorectal Cancer by Ebert, Matthias P.A, Tänzer, Marc, Balluff, Benjamin, Burgermeister, Elke, Kretzschmar, Antje Karen, Hughes, David J, Tetzner, Reimo, Lofton-Day, Catherine, Rosenberg, Robert, Reinacher-Schick, Anke C, Schulmann, Karsten, Tannapfel, Andrea, Hofheinz, Ralf, Röcken, Christoph, Keller, Gisela, Langer, Rupert, Specht, Katja, Porschen, Rainer, Stöhlmacher-Williams, Jan, Schuster, Tibor, Ströbel, Philipp, Schmid, Roland M

“…Patients whose tumors showed methylation and decreased expression of the gene TFAP2E were more than five times as likely as patients with normal TFAP2E gene…”
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Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis by Weichert, Wilko, Dr, Röske, Annika, Gekeler, Volker, PhD, Beckers, Thomas, PhD, Ebert, Matthias PA, Prof, Pross, Matthias, MD, Dietel, Manfred, Prof, Denkert, Carsten, MD, Röcken, Christoph, Prof

“…Summary Background Although histone deacetylases (HDACs) are known to have an important regulatory role in cancer cells, and HDAC inhibitors (HDIs) have…”
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Epigenetic identification of ubiquitin carboxyl‐terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors by Yu, Jun, Tao, Qian, Cheung, Kin F., Jin, Hongchuan, Poon, Fan Fong, Wang, Xian, Li, Hongyu, Cheng, Yuen Y., Röcken, Christoph, Ebert, Matthias P. A., Chan, Anthony T. C., Sung, Joseph J. Y.

“…The ubiquitin carboxyl‐terminal hydrolase L1 (UCHL1) is a carboxyl‐terminal ubiquitin hydrolase regulating cellular ubiquitin levels, recently suggested as a…”
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Preventive Transhepatic Tract Embolisation after Percutaneous Biliary Interventions: A Systematic Review by Hetjens, Svetlana, Rudi, Jochen, Chang, De-Hua, Schmitz, Daniel, Ebert, Matthias P. A.

“…Preventive transhepatic tract embolisation (PTTE) after percutaneous biliary intervention (PBI) may reduce adverse events. The aim of this systematic review…”
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Identification and Confirmation of Increased Fibrinopeptide A Serum Protein Levels in Gastric Cancer Sera by Magnet Bead Assisted MALDI-TOF Mass Spectrometry by Ebert, Matthias P. A, Niemeyer, Dagmar, Deininger, Sören O, Wex, Thomas, Knippig, Claudia, Hoffmann, Juliane, Sauer, Jörg, Albrecht, Wolfgang, Malfertheiner, Peter, Röcken, Christoph

“…Gastric cancer is the second most common malignancy and prognosis remains dismal. The reasons for the poor prognosis are the lack of sensitive serum markers…”
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Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis by Hitkova, Ivana, Yuan, Gang, Anderl, Florian, Gerhard, Markus, Kirchner, Thomas, Reu, Simone, Röcken, Christoph, Schäfer, Claus, Schmid, Roland M, Vogelmann, Roger, Ebert, Matthias P A, Burgermeister, Elke

“…Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by…”
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APC promoter methylation and protein expression in hepatocellular carcinoma by Csepregi, Antal, Röcken, Christoph, Hoffmann, Juliane, Gu, Ping, Saliger, Stephan, Müller, Oliver, Schneider-Stock, Regine, Kutzner, Nadine, Roessner, Albert, Malfertheiner, Peter, Ebert, Matthias P. A.

“…Purpose We investigated the impact of promoter methylation on APC protein expression in patients with hepatocellular carcinoma (HCC). Materials and methods 50…”
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Overexpression of cathepsin B in gastric cancer identified by proteome analysis by Ebert, Matthias P. A., Krüger, Sabine, Fogeron, Marie-Laure, Lamer, Stephanie, Chen, Jie, Pross, Matthias, Schulz, Hans-Ulrich, Lage, Hermann, Heim, Steffen, Roessner, Albert, Malfertheiner, Peter, Röcken, Christoph

“…We aimed to validate an analytical approach based on proteomics on gastric cancer specimens for the identification of new putative diagnostic or prognostic…”
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Meta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Gastric Cancer Risk: A Huge-GSEC Review by Boccia, Stefania, Hung, Rayjean, Ricciardi, Gualtiero, Gianfagna, Francesco, Ebert, Matthias P. A., Fang, Jing-Yuan, Gao, Chang-Ming, Götze, Tobias, Graziano, Francesco, Lacasaña-Navarro, Marina, Lin, Dongxin, López-Carrillo, Lizbeth, Qiao, You-Lin, Shen, Hongbing, Stolzenberg-Solomon, Rachael, Takezaki, Toshiro, Weng, Yu-Rong, Zhang, Fang Fang, van Duijn, Cornelia M., Boffetta, Paolo, Taioli, Emanuela

“…Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate, whose role in gastric carcinogenesis is controversial. The authors…”
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Vascular CXCR4 expression - a novel antiangiogenic target in gastric cancer? by Ingold, Barbara, Simon, Eva, Ungethüm, Ute, Kuban, Ralf-Jürgen, Müller, Berit M, Lupp, Amelie, Neumann, Ulf, Ebert, Matthias P A, Denkert, Carsten, Weichert, Wilko, Schulz, Stefan, Röcken, Christoph

“…G-protein-coupled receptors (GPCRs) are prime candidates for novel cancer prevention and treatment strategies. We searched for differentially expressed GPCRs…”
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Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy by Smeets, Dominiek, Miller, Ian S., O’Connor, Darran P., Das, Sudipto, Moran, Bruce, Boeckx, Bram, Gaiser, Timo, Betge, Johannes, Barat, Ana, Klinger, Rut, van Grieken, Nicole C. T., Cremolini, Chiara, Prenen, Hans, Mazzone, Massimiliano, Depreeuw, Jeroen, Bacon, Orna, Fender, Bozena, Brady, Joseph, Hennessy, Bryan T., McNamara, Deborah A., Kay, Elaine, Verheul, Henk M., Maarten, Neerincx, Gallagher, William M., Murphy, Verena, Prehn, Jochen H. M., Koopman, Miriam, Punt, Cornelis J. A., Loupakis, Fotios, Ebert, Matthias P. A., Ylstra, Bauke, Lambrechts, Diether, Byrne, Annette T.

“…Increased copy number alterations (CNAs) indicative of chromosomal instability (CIN) have been associated with poor cancer outcome. Here, we study CNAs as…”
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Identification of Gastric Cancer Patients by Serum Protein Profiling by Ebert, Matthias P. A, Meuer, Jörn, Wiemer, Jan C, Schulz, Hans-Ulrich, Reymond, Marc A, Traugott, Ulrich, Malfertheiner, Peter, Röcken, Christoph

“…Using surface-enhanced laser desorption ionization mass spectrometry (SELDI/TOF−MS) and ProteinChip technology, coupled with a pattern-matching algorithm and…”
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Updated German guideline on diagnosis and treatment of squamous cell carcinoma and adenocarcinoma of the esophagus by Porschen, Rainer, Fischbach, Wolfgang, Gockel, Ines, Hollerbach, Stephan, Hölscher, Arnulf, Jansen, Petra Lynen, Miehlke, Stephan, Pech, Oliver, Stahl, Michael, Vanhoefer, Udo, Ebert, Matthias P. A.

“…Diagnosis and therapy of esophageal carcinoma is challenging and requires a multidisciplinary approach. The purpose of the updated German guideline “Diagnosis…”
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Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure by Lin, Tao, Wang, Shanshan, Munker, Stefan, Jung, Kyounghwa, Macías‐Rodríguez, Ricardo U., Ruiz‐Margáin, Astrid, Schierwagen, Robert, Liu, Hui, Shao, Chen, Fan, Chunlei, Feng, Rilu, Yuan, Xiaodong, Wang, Sai, Wandrer, Franziska, Meyer, Christoph, Wimmer, Ralf, Liebe, Roman, Kroll, Jens, Zhang, Long, Schiergens, Tobias, ten Dijke, Peter, Teufel, Andreas, Marx, Alexander, Mertens, Peter R., Wang, Hua, Ebert, Matthias P.A., Bantel, Heike, De Toni, Enrico, Trebicka, Jonel, Dooley, Steven, Shin, Donghun, Ding, Huiguo, Weng, Hong‐Lei

“…Background and Aims In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, liver progenitor cells (LPCs) take over key hepatocyte…”
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Systematic evaluation of the miRNA-ome and its downstream effects on mRNA expression identifies gastric cancer progression by Tchernitsa, Oleg, Kasajima, Atsuko, Schäfer, Reinhold, Kuban, Ralf-Jürgen, Ungethüm, Ute, Györffy, Balazs, Neumann, Ulf, Simon, Eva, Weichert, Wilko, Ebert, Matthias PA, Röcken, Christoph

“…We investigated the differential expression of Dicer and Drosha, as well as that of microRNA (miRNA), in adjacent normal and tumour samples of patients with…”
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Promoter methylation of the Wnt/β‐catenin signaling antagonist Dkk‐3 is associated with poor survival in gastric cancer by Yu, Jun, Tao, Qian, Cheng, Yuen Y., Lee, Kwan Y., Ng, Simon S. M., Cheung, Kin F., Tian, Linwei, Rha, Sun Y., Neumann, Ulf, Röcken, Christoph, Ebert, Matthias P. A., Chan, Francis K. L., Sung, Joseph J. Y.

“…BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the…”
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Caveats of caveolin-1 in cancer progression by Burgermeister, Elke, Liscovitch, Mordechai, Röcken, Christoph, Schmid, Roland M, Ebert, Matthias P.A

“…Abstract Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately gained recognition as a stage- and tissue-specific…”
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Molecular Imaging of Proliferation and Glucose Utilization: Utility for Monitoring Response and Prognosis after Neoadjuvant Therapy in Locally Advanced Gastric Cancer by Ott, Katja, Herrmann, Ken, Schuster, Tibor, Langer, Rupert, Becker, Karen, Wieder, Hinrich A., Wester, Hans-Jürgen, Siewert, Jörg-Rüdiger, Büschenfelde, Christian Meyer zum, Buck, Andreas K., Wilhelm, Dirk, Ebert, Matthias P. A., Peschel, Christian, Schwaiger, Markus, Lordick, Florian, Krause, Bernd Joachim

“…Background Metabolic imaging of gastric cancer is limited due to the 30% of primary tumors that are not 18 F-fluorodeoxyglucose (FDG) avid. In contrast, the…”
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