Search Results - "Eberstål, Sofia"

Identification of two distinct mesenchymal stromal cell populations in human malignant glioma by Svensson, Andreas, Ramos-Moreno, Tania, Eberstål, Sofia, Scheding, Stefan, Bengzon, Johan

“…Gene profiling has revealed that malignant gliomas can be divided into four distinct molecular subtypes, where tumors with a mesenchymal gene expression are…”
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Low‐dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo by Stefani, Francesca Romana, Eberstål, Sofia, Vergani, Stefano, Kristiansen, Trine A., Bengzon, Johan

“…Solid tumors, including gliomas, still represent a challenge to clinicians and first line treatments often fail, calling for new paradigms in cancer therapy…”
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Intratumoral COX‐2 inhibition enhances GM‐CSF immunotherapy against established mouse GL261 brain tumors by Eberstål, Sofia, Sandén, Emma, Fritzell, Sara, Darabi, Anna, Visse, Edward, Siesjö, Peter

“…Immunotherapy has shown effectiveness against experimental malignant brain tumors, but the clinical results have been less convincing most likely due to…”
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Intratumoral temozolomide synergizes with immunotherapy in a T cell-dependent fashion by Fritzell, Sara, Sandén, Emma, Eberstål, Sofia, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…Despite temozolomide (TMZ) treatment, the prognosis for patients with glioblastoma multiforme is still dismal. As dose escalation of TMZ is limited by systemic…”
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A standardized and reproducible protocol for serum-free monolayer culturing of primary paediatric brain tumours to be utilized for therapeutic assays by Sandén, Emma, Eberstål, Sofia, Visse, Edward, Siesjö, Peter, Darabi, Anna

“…In vitro cultured brain tumour cells are indispensable tools for drug screening and therapeutic development. Serum-free culture conditions tentatively preserve…”
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IFNγ in combination with IL-7 enhances immunotherapy in two rat glioma models by Fritzell, Sara, Eberstål, Sofia, Sandén, Emma, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…Abstract Peripheral immunization, using a combination of interferon-gamma (IFNγ)- and interleukin-7 (IL-7)-producing tumor cells, eradicated 75% of…”
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Immunizations with unmodified tumor cells and simultaneous COX-2 inhibition eradicate malignant rat brain tumors and induce a long-lasting CD8+ T cell memory by Eberstål, Sofia, Fritzell, Sara, Sandén, Emma, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…Abstract Malignant brain tumors induce pronounced immunosuppression, which diminishes immune responses generated by immunotherapy. Here we report that…”
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Inhibition of cyclooxygenase-2 enhances immunotherapy against experimental brain tumors by Eberstål, Sofia, Badn, Wiaam, Fritzell, Sara, Esbjörnsson, Magnus, Darabi, Anna, Visse, Edward, Siesjö, Peter

“…Glioblastoma multiforme is the most common and aggressive malignant brain tumor in humans, and the prognosis is very poor despite conventional therapy…”
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L ow‐dose irradiated mesenchymal stromal cells break tumor defensive properties in vivo by Stefani, Francesca Romana, Eberstål, Sofia, Vergani, Stefano, Kristiansen, Trine A., Bengzon, Johan

“…Solid tumors, including gliomas, still represent a challenge to clinicians and first line treatments often fail, calling for new paradigms in cancer therapy…”
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Cure of established GL261 mouse gliomas after combined immunotherapy with GM‐CSF and IFNγ is mediated by both CD8+ and CD4+ T‐cells by Smith, Karin Enell, Fritzell, Sara, Badn, Wiaam, Eberstål, Sofia, Janelidze, Shorena, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…We were the first to demonstrate that combined immunotherapy with GM‐CSF producing GL261 cells and recombinant IFNγ of preestablished GL261 gliomas could cure…”
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Intratumorally implanted mesenchymal stromal cells potentiate peripheral immunotherapy against malignant rat gliomas by Ströjby, Salina, Eberstål, Sofia, Svensson, Andreas, Fritzell, Sara, Bexell, Daniel, Siesjö, Peter, Darabi, Anna, Bengzon, Johan

“…Abstract Bone marrow-derived mesenchymal stromal cells (MSCs) target glioma extensions and micro-satellites efficiently when implanted intratumorally. Here, we…”
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Abstract 2409: Enhanced cell-based immunotherapy by IFNγ, IL-7 or COX-2 inhibition in a rat glioma model by Fritzell, Sara V., Eberstål, Sofia, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…Abstract Introduction: Glioblastoma multiforme (GBM) is the most common brain tumor in adults and the median survival time after diagnosis is less than a year…”
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Abstract LB-321: Changing the route of immunization determines outcome in immunotherapy of experimental brain tumors: Translation in development by Darabi, Anna C., Sande'n, Emma, Eberstål, Sofia, Janelidze, Shorena, Visse, Edward, Siesjö, Peter

“…Abstract Introduction: Based on our previous experimental result we have performed a clinical trial at the Lund University Hospital, with immunotherapy using…”
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Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells by Smith, Karin Enell, Fritzell, Sara, Badn, Wiaam, Eberstål, Sofia, Janelidze, Shorena, Visse, Edward, Darabi, Anna, Siesjö, Peter

“…We were the first to demonstrate that combined immunotherapy with GM-CSF producing GL261 cells and recombinant IFNgamma of preestablished GL261 gliomas could…”
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Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNy is mediated by both CD8+ and CD4+ T-cells by SMITH, Karin Enell, FRITZELL, Sara, BADN, Wiaam, EBERSTAL, Sofia, JANELIDZE, Shorena, VISSE, Edward, DARABI, Anna, SIESJÖ, Peter

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