Search Results - "Eberlein, Catherine A"

Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models by Eberlein, Catherine A, Stetson, Daniel, Markovets, Aleksandra A, Al-Kadhimi, Katherine J, Lai, Zhongwu, Fisher, Paul R, Meador, Catherine B, Spitzler, Paula, Ichihara, Eiki, Ross, Sarah J, Ahdesmaki, Miika J, Ahmed, Ambar, Ratcliffe, Laura E, O'Brien, Elizabeth L Christey, Barnes, Claire H, Brown, Henry, Smith, Paul D, Dry, Jonathan R, Beran, Garry, Thress, Kenneth S, Dougherty, Brian, Pao, William, Cross, Darren A E

“…Resistance to targeted EGFR inhibitors is likely to develop in EGFR-mutant lung cancers. Early identification of innate or acquired resistance mechanisms to…”
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Abstract B05: Discovery, validation and targeting of novel synthetic lethal interactions in academic drug discovery by March, H. Nikki, Chapman, Phil, Blaikley, Elizabeth, Eberlein, Catherine A., Cockerill, Mark, Hitchin, Samantha, Waddell, Ian D., Ogilvie, Donald

“…The identification of novel oncology targets for small molecule drug discovery is becoming increasingly challenging despite 10-15% of the human genome…”
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