Search Results - "Eberhardt, Christine"

Racemic and chiral lactams as potent, selective and functionally active CCR4 antagonists by Newhouse, Bradley, Allen, Shelley, Fauber, Benjamin, Anderson, Aaron S., Eary, C. Todd, Hansen, Joshua D., Schiro, Justin, Gaudino, John J., Laird, Ellen, Chantry, David, Eberhardt, Christine, Burgess, Laurence E.

“…A series of racemic and chiral, nonracemic lactams that display high binding affinities, functional chemotaxis antagonism, and selectivity toward CCR4 are…”
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Human Lysophosphatidic Acid Acyltransferase by Eberhardt, Christine, Gray, Patrick W., Tjoelker, Larry W.

“…Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate (LPA)) is a phospholipid with diverse biological activities. The mediator serves as an intermediate in…”
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Abstract A252: A phase 1 study of ARRY-382, an oral inhibitor of colony-stimulating factor-1 receptor (CSF1R), in patients with advanced or metastatic cancers by Bendell, Johanna C., Tolcher, Anthony W., Jones, Suzanne F., Beeram, Muralidhar, Infante, Jeffrey R., Larsen, Paul, Rasor, Kevin, Garrus, Jennifer E., Li, Jinfang, Cable, P. Louann, Eberhardt, Christine, Schreiber, Jennifer, Rush, Selena, Wood, Kenneth W., Barrett, Emma, Patnaik, Amita

“…Introduction: Within the tumor microenvironment, CSF1R signaling is thought to play an important role in recruitment and differentiation of tumor-associated…”
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Safety and Efficacy Of ARRY-502, a Potent, Selective, Oral CRTh2 Antagonist, In Patients With Mild To Moderate Th2-Driven Asthma by Wenzel, Sally E., MD, FAAAAI, Hopkins, Robert, Saunders, Michael, Dr, Chantry, David, Anderson, Lisa, Aitchison, Roger, Eberhardt, Christine, Bell, Stacie, Cole, Jeremy, Dr, Wolfe, James, Dr, Spector, Sheldon L., Dr, Sher, Lawrence D., Dr, Kerwin, Edward M., Dr, Burgess, Larry, Dr

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Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists by Allen, Shelley, Newhouse, Bradley, Anderson, Aaron S., Fauber, Benjamin, Allen, Andrew, Chantry, David, Eberhardt, Christine, Odingo, Joshua, Burgess, Laurence E.

“…Substituted thiazolidinones were identified as CCR4 antagonists from high throughput screening. Subsequent lead optimization efforts resulted in defined…”
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Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q34.3 by Eberhardt, C, Gray, P W, Tjoelker, L W

“…Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate (LPA)) is a phospholipid with diverse biological activities. The mediator serves as an intermediate in…”
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Identification and characterization of a potent and selective antagonist of the prostaglandin D2 receptor (94.23) by Eberhardt, Christine, Wright, Dale, Gomez, Anna, Cook, Adam, Doherty, George, Corrette, Christopher, Hunt, Kevin, Clark, Christopher, Kim, Ganghyeok, Romoff, Todd, Delisle, Kirk, Hayter, Laura, Neale, Jason, Dean, Brian, Chantry, David, Carter, Laura, Burgess, Laurence E

“…Prostaglandin D2 (PGD2) is a potent lipid mediator released from activated mast cells during allergic responses which exerts its pro-inflammatory effects…”
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Synthesis of spirolactams and spiropiperidines as CCR4 receptor antagonists by Hansen, Joshua D., Newhouse, Bradley J., Allen, Shelley, Anderson, Aaron, Eary, Todd, Schiro, Justin, Gaudino, John, Laird, Ellen, Allen, Andrew C., Chantry, David, Eberhardt, Christine, Burgess, Laurence E.

“…The synthesis of racemic and non-racemic spirocyclic lactams that display high binding affinity toward CCR4 is described. Two distinct series of spirocycles…”
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Values Education: Dealing with the Responsibility by Eberhardt, Christine M

“…An annotated listing of over 80 journal articles and research reports on values education, a brief summary of the opinions and findings in the articles, and…”
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