Search Results - "Ebanks, Brad"
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A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer
Published in PloS one (24-07-2023)“…High-resolution respirometry methods allow for the assessment of oxygen consumption by the electron transfer systems within cells, tissue samples, and isolated…”
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Mitochondrial ATP Synthase is a Target of Oxidative Stress in Neurodegenerative Diseases
Published in Frontiers in molecular biosciences (14-02-2022)“…The mitochondrial ATP synthase is responsible for the production of cellular ATP, and it does so by harnessing the membrane potential of the mitochondria that…”
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Sequence and structure comparison of ATP synthase F0 subunits 6 and 8 in notothenioid fish
Published in PloS one (01-10-2021)“…Mitochondrial changes such as tight coupling of the mitochondria have facilitated sustained oxygen and respiratory activity in haemoglobin-less icefish of the…”
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A Common Anaesthetic, MS-222, Alters Measurements Made Using High-Resolution Respirometry in the Three-Spined Stickleback (Gasterosteus aculeatus)
Published in Fishes (01-01-2023)“…Submersion in the anaesthetic MS-222 is a well-established and effective method used during the euthanasia of fish, but the consequences of treatment with this…”
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Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex
Published in International journal of molecular sciences (27-10-2021)“…Ageing is a major risk factor for many of the most prevalent diseases, including neurodegenerative diseases, cancer, and heart disease. As the global…”
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Quantitative Proteomics and Network Analysis of Differentially Expressed Proteins in Proteomes of Icefish Muscle Mitochondria Compared with Closely Related Red-Blooded Species
Published in Biology (Basel, Switzerland) (26-07-2022)“…Antarctic icefish are extraordinary in their ability to thrive without haemoglobin. We wanted to understand how the mitochondrial proteome has adapted to the…”
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Experience of an NIHR Clinical Lectureship (medical/dental) and the determining factors for a clinical academic career post lectureship: a mixed-method evaluation
Published in BMJ open (17-11-2023)“…ObjectivesThe objective of this study is to investigate early-to-late postdoctoral clinical academic progression and the experiences of NIHR Clinical…”
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Mitochondrial Haemoglobin Is Upregulated with Hypoxia in Skeletal Muscle and Has a Conserved Interaction with ATP Synthase and Inhibitory Factor 1
Published in Cells (Basel, Switzerland) (01-03-2023)“…The globin protein superfamily has diverse functions. Haemoglobin has been found in non-erythroid locations, including within the mitochondria. Using…”
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ATP synthase and Alzheimer's disease: putting a spin on the mitochondrial hypothesis
Published in Aging (Albany, NY.) (27-08-2020)“…It is estimated that over 44 million people across the globe have dementia, and half of these cases are believed to be Alzheimer's disease (AD). As the…”
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Proteomic analysis of the ATP synthase interactome in notothenioids highlights a pathway that inhibits ceruloplasmin production
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-08-2022)“…Antarctic notothenioids have unique adaptations that allow them to thrive in subzero Antarctic waters. Within the suborder Notothenioidei, species of the…”
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Sequence and structure comparison of ATP synthase F.sub.0 subunits 6 and 8 in notothenioid fish
Published in PloS one (06-10-2021)“…Mitochondrial changes such as tight coupling of the mitochondria have facilitated sustained oxygen and respiratory activity in haemoglobin-less icefish of the…”
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The dysregulated Pink1- Drosophila mitochondrial proteome is partially corrected with exercise
Published in Aging (Albany, NY.) (15-06-2021)“…One of the genes which has been linked to the onset of juvenile/early onset Parkinson’s disease (PD) is PINK1. There is evidence that supports the therapeutic…”
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Corrigendum: Acute imidacloprid exposure alters mitochondrial function in bumblebee flight muscle and brain
Published in Frontiers in insect science (22-04-2024)“…[This corrects the article DOI: 10.3389/finsc.2021.765179.]…”
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Acute Imidacloprid Exposure Alters Mitochondrial Function in Bumblebee Flight Muscle and Brain
Published in Frontiers in insect science (01-12-2021)“…Mitochondria are intracellular organelles responsible for cellular respiration with one of their major roles in the production of energy in the form of ATP…”
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