Search Results - "Ebady, Rhodaba"
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The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells
Published in PLoS pathogens (01-09-2016)“…Syphilis is a chronic disease caused by the bacterium Treponema pallidum subsp. pallidum. Treponema pallidum disseminates widely throughout the host and…”
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Biomechanics of Borrelia burgdorferi Vascular Interactions
Published in Cell reports (Cambridge) (06-09-2016)“…Systemic dissemination of microbes is critical for progression of many infectious diseases and is associated with most mortality due to bacterial infection…”
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Journal Article -
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Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete
Published in Scientific reports (08-05-2017)“…Treponema pallidum subsp. pallidum , the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate…”
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Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen
Published in PloS one (24-06-2016)“…Insulin-insufficient type 1 diabetes is associated with attenuated bactericidal function of neutrophils, which are key mediators of innate immune responses to…”
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Plasma fibronectin stabilizes Borrelia burgdorferi– endothelial interactions under vascular shear stress by a catch-bond mechanism
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2017)“…Bacterial dissemination via the cardiovascular system is the most common cause of infection mortality. A key step in dissemination is bacterial interaction…”
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Quantifying pulmonary vein antrum contact area with novel dual-sized cryoballoon to optimize pulmonary vein isolation
Published in Heart rhythm (01-11-2024)Get full text
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Contributions of the B. burgdorferi Vascular Adhesin BBK32 and Endothelial Surface Receptors to Mechanical Stabilization of Bacterial – Vascular Interactions
Published 01-01-2020“…Systemic dissemination of microbes is critical for progression of many infectious diseases and is associated with most mortality due to bacterial infection…”
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Dissertation -
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Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules
Published in Molecular microbiology (01-12-2012)“…Summary Systemic dissemination of microbial pathogens permits microbes to spread from the initial site of infection to secondary target tissues and is…”
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Journal Article -
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Flow-Tolerant Adhesion of a Bacterial Pathogen to Human Endothelial Cells Through Interaction With Biglycan
Published in The Journal of infectious diseases (15-05-2016)“…Background. Bacterial pathogens causing systemic infections disseminate from the initial infection focus to the target organs usually through the blood…”
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Journal Article -
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Infection with the Lyme disease pathogen suppresses innate immunity in mice with diet‐induced obesity
Published in Cellular microbiology (01-05-2017)“…Obesity is a major global public health concern. Immune responses implicated in obesity also control certain infections. We investigated the effects of…”
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Journal Article -
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The Structure of Treponema pallidum Tp0751
Published in PLoS pathogens (28-09-2016)Get full text
Journal Article