Search Results - "Eaton, Samuel C"

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma by Bailey, Sean T., Smith, Aleisha M., Kardos, Jordan, Wobker, Sara E., Wilson, Harper L., Krishnan, Bhavani, Saito, Ryoichi, Lee, Hyo Jin, Zhang, Jing, Eaton, Samuel C., Williams, Lindsay A., Manocha, Ujjawal, Peters, Dorien J., Pan, Xinchao, Carroll, Thomas J., Felsher, Dean W., Walter, Vonn, Zhang, Qing, Parker, Joel S., Yeh, Jen Jen, Moffitt, Richard A., Leung, Janet Y., Kim, William Y.

“…Renal carcinoma is a common and aggressive malignancy whose histopathogenesis is incompletely understood and that is largely resistant to cytotoxic…”
Get full text

Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling by Quintana, Megan T, Parry, Traci L, He, Jun, Yates, Cecelia C, Sidorova, Tatiana N, Murray, Katherine T, Bain, James R, Newgard, Christopher B, Muehlbauer, Michael J, Eaton, Samuel C, Hishiya, Akinori, Takayama, Shin, Willis, Monte S

“…The Bcl2-associated anthanogene (BAG) 3 protein is a member of the BAG family of cochaperones, which supports multiple critical cellular processes, including…”
Get full text

AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System by Rockwell, Hannah E., McCurdy, Victoria J., Eaton, Samuel C., Wilson, Diane U., Johnson, Aime K., Randle, Ashley N., Bradbury, Allison M., Gray-Edwards, Heather L., Baker, Henry J., Hudson, Judith A., Cox, Nancy R., Sena-Esteves, Miguel, Seyfried, Thomas N., Martin, Douglas R.

“…Sandhoff disease (SD) is an autosomal recessive neurodegenerative disease caused by a mutation in the gene for the β-subunit of β-N-acetylhexosaminidase (Hex),…”
Get full text

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma by Moffitt, Richard A, Marayati, Raoud, Flate, Elizabeth L, Volmar, Keith E, Loeza, S Gabriela Herrera, Hoadley, Katherine A, Rashid, Naim U, Williams, Lindsay A, Eaton, Samuel C, Chung, Alexander H, Smyla, Jadwiga K, Anderson, Judy M, Kim, Hong Jin, Bentrem, David J, Talamonti, Mark S, Iacobuzio-Donahue, Christine A, Hollingsworth, Michael A, Yeh, Jen Jen

“…Jen Jen Yeh and colleagues apply statistical methods to separate tumor, stroma and normal tissue gene expression signatures from pancreatic ductal…”
Get full text

Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo by Mota, Roberto, Parry, Traci L., Yates, Cecelia C., Qiang, Zhaoyan, Eaton, Samuel C., Mwiza, Jean Marie, Tulasi, Deepthi, Schisler, Jonathan C., Patterson, Cam, Zaglia, Tania, Sandri, Marco, Willis, Monte S.

“…The muscle-specific ubiquitin ligase atrogin-1 (MAFbx) has been identified as a critical regulator of pathologic and physiological cardiac hypertrophy; it…”
Get full text

251. Defining Conserved Structural Components of the AAV Capsid That Enable Tissue-Specific Transduction Following Systemic Administration by Warischalk, Jayme K., Eaton, Samuel C., Samulski, R. Jude

Get full text

Pharmacological Inhibition of p38/MAPK Improves Cardiac Function in Cardiac‐specific Bag3‐P209L Transgenic Mice by Eaton, Samuel C., Takayama, Shinuchi, Sidorova, Tatiana N., Murray, Katherine T., Willis, Monte S.

“…Abstract only Bag3 (Bcl‐2‐associated athanogene‐3) is a small heat shock protein expressed predominantly in cardiac and skeletal muscle that regulates…”
Get full text

Abstract 18238: Cardiomyocyte-specific Bag3+ Mutation P209L Induces Mitochondrial Fragmentation, Increased Apoptosis, and Activates p38 Signaling in vivo by Quintana, Megan T, Eaton, Samuel C, Yates, Cecelia C, Takayama, Shinichi, Willis, Monte S

“…IntroductionThere are 6 members of the Bcl2-related anthanogene (BAG) protein family, which act as co-chaperones expressed at high levels in skeletal and…”
Get full text