Search Results - "Eaton, Emma D."
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Extracellular Alpha-Synuclein Promotes a Neuroinhibitory Secretory Phenotype in Astrocytes
Published in Life (Basel, Switzerland) (08-09-2020)“…Multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are α-synucleinopathies that exhibit widespread astrogliosis as a component of the…”
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Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration
Published in PloS one (27-04-2011)“…One of the key pathological features of AD is the formation of insoluble amyloid plaques. The major constituent of these extracellular plaques is the…”
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Human Ischaemic Cascade Studies Using SH-SY5Y Cells: a Systematic Review and Meta-Analysis
Published in Translational stroke research (01-12-2018)“…Low translational yield for stroke may reflect the focus of discovery science on rodents rather than humans. Just how little is known about human neuronal…”
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The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions
Published in Molecular and cellular neuroscience (01-03-2015)“…Multiple system atrophy (MSA) exhibits widespread astrogliosis together with α-synuclein (α-syn) glial cytoplasmic inclusions (GCIs) in mature…”
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The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Aβ Aggregation and Toxicity in Rat Cortical Neurons
Published in PloS one (11-08-2010)“…Background A major pathological hallmark of AD is the deposition of insoluble extracellular β-amyloid (Aβ) plaques. There are compelling data suggesting that…”
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6
The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons
Published in PloS one (11-08-2010)“…A major pathological hallmark of AD is the deposition of insoluble extracellular beta-amyloid (Abeta) plaques. There are compelling data suggesting that Abeta…”
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7
Tg2576 Cortical Neurons That Express Human Ab Are Susceptible to Extracellular A[beta]-Induced, K.sup.+ Efflux Dependent Neurodegeneration
Published in PloS one (27-04-2011)“…Background One of the key pathological features of AD is the formation of insoluble amyloid plaques. The major constituent of these extracellular plaques is…”
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8
The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated A[beta] Aggregation and Toxicity in Rat Cortical Neurons
Published in PloS one (11-08-2010)“…Background A major pathological hallmark of AD is the deposition of insoluble extracellular [beta]-amyloid (A[beta]) plaques. There are compelling data…”
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9
The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Ab Aggregation and Toxicity in Rat Cortical Neurons
Published in PloS one (11-08-2010)“…A major pathological hallmark of AD is the deposition of insoluble extracellular b-amyloid (Ab) plaques. There are compelling data suggesting that Ab…”
Get full text
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