Search Results - "Easty, D J"

Brachyury-Related Transcription Factor Tbx2 and Repression of the Melanocyte-Specific TRP-1 Promoter by Carreira, S., Dexter, T. J., Yavuzer, U., Easty, D. J., Goding, C. R.

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Protein tyrosine kinases in malignant melanoma by Easty, D J, Bennett, D C

“…Protein tyrosyl phosphorylation is an essential component in intracellular signalling, with diverse and crucial functions including mediation of cell…”
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Microarray analysis of phosphatase gene expression in human melanoma by McArdle, L., Rafferty, M.M., Satyamoorthy, K., Maelandsmo, G.M., Dervan, P.A., Herlyn, M., Easty, D.J.

“…Summary Background  Tyrosine phosphate is abnormally elevated in malignant melanoma, and this has been interpreted to reflect the activity of oncogenic protein…”
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Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma by Easty, David J., Mitchell, Philip J., Patel, Ketan, Florenes, Vivi Ann, Spritz, Richard A., Bennett, Dorothy C.

“…Protein tyrosine kinases (PTKs) have been implicated in the development of many common human tumours including melanoma. Previously we isolated PTK gene…”
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Requirement for focal adhesion kinase in tumor cell adhesion by MAUNG, K, EASTY, D. J, HILL, S. P, BENNETT, D. C

“…Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase and a major phosphotyrosine-containing protein. FAK is found in cell-matrix attachment…”
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Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis by Easty, D J, Herlyn, M, Bennett, D C

“…Protein tyrosine kinases have been implicated in tumor initiation and progression. Here we used Northern blotting to study expression of their genes in…”
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Protein B61 as a new growth factor : expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression by EASTY, D. J, GUTHRIE, B. A, MAUNG, K, FARR, C. J, LINDBERG, R. A, TOSO, R. J, HERLYN, M, BENNETT, D. C

“…Epithelial cell kinase (ECK) is a receptor protein tyrosine kinase, the role of which in melanoma biology is unclear. Here we studied the role of ECK during…”
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The POU domain transcription factor Brn-2: elevated expression in malignant melanoma and regulation of melanocyte-specific gene expression by Eisen, T, Easty, D J, Bennett, D C, Goding, C R

“…Previous work has shown that melanoma cell lines express a distinct octamer binding protein. Given the role of octamer-binding proteins in cell differentiation…”
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Tyrosine phosphate in melanoma progression by Mcardle, L., Bergin, O., Fallowfield, M.E., Dervan, P.A., Easty, D.J.

“…Summary  Background Cellular tyrosine phosphorylation is regulated by two large families of enzymes. Protein tyrosine kinases (PTK) mediate addition, and…”
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Expression of NM23 in human melanoma progression and metastasis by EASTY, D. J, MAUNG, K, LASCU, I, VERON, M, FALLOWFIELD, M. E, HART, I. R, BENNETT, D. C

“…NM23 is a putative metastasis-suppressor gene for some human cancers. Here we have studied NM23 expression during melanoma progression using Northern blotting…”
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Up‐regulation of ephrin‐a1 during melanoma progression by Easty, David J., Hill, Simon P., Hsu, Mei‐Yu, Fallowfield, Mary E., Flørenes, Vivi Ann, Herlyn, Meenhard, Bennett, Dorothy C.

“…Ephrin‐A1, formerly called B61, is a new melanoma growth factor; it is angiogenic and chemoattractant for endothelial cells. EPH‐A2, or ECK (a receptor for…”
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Novel and Known Protein Tyrosine Kinases and Their Abnormal Expression in Human Melanoma by Easty, David J, Ganz, Sue E, Farr, Christine J, Lai, Cary, Herlyn, Meenhard, Bennett, Dorothy C

“…We have used the polymerase chain reaction and Northern blotting to identify protein tyrosine kinases that may play an an important role in the process of…”
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A study of ras gene mutations in colonic adenomas from familial polyposis coli patients by Farr, C J, Marshall, C J, Easty, D J, Wright, N A, Powell, S C, Paraskeva, C

“…Using an in vitro amplification step (polymerase chain reaction) followed by oligonucleotide dot blot analysis, DNA samples from 29 familial polyposis coli…”
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Protein Tyrosine Phosphatase Genes Downregulated in Melanoma by McArdle, Linda, Rafferty, Mairin, Bergin, Orla, Easty, David J., Mælandsmo, Gunhild M., Farr, Christine J., Dervan, Peter A., O'Loughlin, Sean, Herlyn, Meenhard

“…Phospho-tyrosine levels are increased in melanoma, apparently consistent with reports of elevated protein tyrosine kinase activity. Some protein tyrosine…”
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Melanosomal defects in melanocytes from mice lacking expression of the pink-eyed dilution gene: correction by culture in the presence of excess tyrosine by Rosemblat, S, Sviderskaya, E V, Easty, D J, Wilson, A, Kwon, B S, Bennett, D C, Orlow, S J

“…Mutations in the murine pink-eyed dilution (p) gene, or its human homologue P, result in oculocutaneous albinism. Melanocytes cultured from mice lacking p gene…”
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A study of protein synthesis in cells cultured from involved psoriatic skin by Easty, D J, Patel, K, Otto, W R, Dunn, M J, Kiil, J, Evans, D J

“…Using histochemical techniques an abnormal programme of epidermal differentiation has been well documented in psoriasis. In order to characterise further the…”
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Cloning of the murine homolog of the ocular albinism type 1 (OA1) gene: sequence, genomic structure, and expression analysis in pigment cells by Bassi, M T, Incerti, B, Easty, D J, Sviderskaya, E V, Ballabio, A

“…We report the isolation of the mouse homolog of OA1, the gene responsible for ocular albinism type 1. The mouse Oa1 gene encodes a putative protein of 405…”
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Cloning and characterisation of the chicken gene encoding the telomeric protein TRF2 by Konrad, Jonathan P, Mills, Walter, Easty, David J, Farr, Christine J

“…The telomere-associated protein TRF2 binds as a homodimer to double-stranded (TTAGGG)n arrays in vitro and localises to chromosome ends in vivo. Inhibition of…”
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Impaired growth and differentiation of diploid but not immortal melanoblasts from endothelin receptor B mutant (piebald) mice by Sviderskaya, Elena V., Easty, David J., Bennett, Dorothy C.

“…Endothelin 3 (Edn3) and its preferred receptor, endothelin receptor B (Ednrb), are implicated in development, especially that of two neural‐crest‐derived cell…”
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Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3 by Critcher, R, Stitson, R N, Wade-Martins, R, Easty, D J, Farr, C J

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