Search Results - "Easterbrook, P J"

Incidence and Risk Factors for Immune Reconstitution Inflammatory Syndrome in an Ethnically Diverse HIV Type 1–Infected Cohort by Ratnam, I., Chiu, C., Kandala, N.-B., Easterbrook, P. J.

“…Background. It is estimated that 10%–25% of patients who start highly active antiretroviral therapy (HAART) experience immune reconstitution inflammatory…”
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Wide variation in estimates of global prevalence and burden of chronic hepatitis B and C infection cited in published literature by Basnayake, S. K., Easterbrook, P. J.

“…Summary To evaluate the extent of heterogeneity in global estimates of chronic hepatitis B (HBV) and C (HCV) cited in the published literature, we undertook a…”
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Impact of human immunodeficiency virus (HIV) infection on the progression of liver fibrosis in hepatitis C virus infected patients by Mohsen, A H, Easterbrook, P J, Taylor, C, Portmann, B, Kulasegaram, R, Murad, S, Wiselka, M, Norris, S

“…Objectives: To compare the rate of hepatic fibrosis progression in hepatitis C virus (HCV) infected and human immunodeficiency virus (HIV)-HCV coinfected…”
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Hepatitis C: global epidemiology and strategies for control by Lanini, S., Easterbrook, P.J., Zumla, A., Ippolito, G.

“…It is estimated that globally there are approximately 100 million persons with serological evidence of current or past HCV infection, and that HCV causes about…”
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Publication bias in clinical research by Easterbrook, P J, Berlin, J A, Gopalan, R, Matthews, D R

“…In a retrospective survey, 487 research projects approved by the Central Oxford Research Ethics Committee between 1984 and 1987, were studied for evidence of…”
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The Changing Pattern of AIDS-defining Illnesses with the Introduction of Highly Active Antiretroviral Therapy (HAART)in a London Clinic by Ives, N.J., Gazzard, B.G., Easterbrook, P.J.

“…Objectives:To quantify the progressive impact of combination antiretroviral therapy (ART) on the incidence of AIDS-defining illnesses (ADIs) over a 9-year…”
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Sexual risk behaviours and sexual health outcomes among heterosexual black Caribbeans: comparing sexually transmitted infection clinic attendees and national probability survey respondents by Gerver, S M, Easterbrook, P J, Anderson, M, Solarin, I, Elam, G, Fenton, K A, Garnett, G, Mercer, C H

“…We compared sociodemographic characteristics, sexual risk behaviours and sexual health experiences of 266 heterosexual black Caribbeans recruited at a London…”
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The metabolic toxicities of antiretroviral therapy by Herman, J S, Easterbrook, P J

“…Since the adoption of highly active antiretroviral therapy (HAART) in the mid-1990s, certain metabolic toxicities have been increasingly recognized. These…”
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Comparison between HIV‐ and CMV‐specific T cell responses in long‐term HIV infected donors by PAPAGNO, L., APPAY, V., SUTTON, J., ROSTRON, T., GILLESPIE, G. M. A., OGG, G. S., KING, A., MAKADZANHGE, A. T., WATERS, A., BALOTTA, C., VYAKARNAM, A., EASTERBROOK, P. J., ROWLAND‐JONES, S. L.

“…Summary The mechanisms underlying non‐progression in HIV‐1 infection are not well understood; however, this state has been associated previously with strong…”
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CD4 responses to conserved HIV‐1 T helper epitopes show both negative and positive associations with virus load in chronically infected subjects by BOAZ, M. J., WATERS, A., MURAD, S., EASTERBROOK, P. J., D’SOUSA, E., VAN WHEELEY, C., VYAKARNAM, A.

“…SUMMARY Characterization of immune responses to immunodominant CD4 epitopes in HIV‐1 that are associated with control of HIV infection could be used to…”
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Epidemiological risk factors for hypersensitivity reactions to abacavir by Easterbrook, PJ, Waters, A, Murad, S, Ives, N, Taylor, C, King, D, Vyakarnam, A, Thorburn, D

“…We investigated risk factors for hypersensitivity reactions (HSR) to abacavir in a case–control study. In a multivariate analysis, white race [odds ratio (OR),…”
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Patterns and predictors of the use of different antiretroviral drug regimens at treatment initiation in the UK by Easterbrook, PJ, Phillips, AN, Hill, T, Matthias, R, Fisher, M, Gazzard, B, Gilson, R, Scullard, G, Johnson, M, Dunn, DT, Orkin, C, Anderson, J, Schwenk, A, Leen, C, Sabin, CA

“…Background We describe the patterns of antiretroviral drug use at treatment initiation from 1996 to 2005 in a large UK multicentre cohort. Methods We examined…”
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Chemokine Receptor Polymorphisms and Human Immunodeficiency Virus Disease Progression by Easterbrook, Philippa J., Rostron, Tim, Ives, Natalie, Troop, Maxine, Gazzard, Brian G., Rowland-Jones, Sarah L.

“…The role of polymorphisms in genes encoding chemokines and their receptors (CCR2B, SDF-1, and the promoter region of CCR5) in human immunodeficiency virus…”
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Non-progression in HIV infection by Easterbrook, P J

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HLA-Cw0602 and HIV-associated psoriasis by MALLON, E, YOUNG, D, BUNCE, M, GOTCH, F. M, EASTERBROOK, P. J, NEWSON, R, BUNKER, C. B

“…The aetiopathogenesis of psoriasis is unknown, but genetic and environmental factors may be involved. Psoriasis may not be one disease but a cutaneous…”
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Long-term non-progression in HIV infection: Definitions and epidemiological issues by Easterbrook, Philippa J.

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The relationship of psychological variables and disease progression among long-term HIV-infected men by Psychd, S T, Troop, M, Burgess, A P, Button, J, Goodall, R, Flynn, R, Gazzard, B G, Catalán, J, Easterbrook, P J

“…This study investigated the contribution of psychological factors to disease progression among long-term HIV-1 infected gay men. Participants completed…”
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An association of disseminated Mycoplasma fermentans in HIV-1 positive patients with non-Hodgkin's lymphoma by Ainsworth, J G, Easterbrook, P J, Clarke, J, Gilroy, C B, Taylor-Robinson, D

“…We examined the relationship between the haematogenous dissemination of Mycoplasma fermentans and non-Hodgkin's lymphoma (NHL) in 265 HIV-1 positive patients…”
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Low Prevalence of Antiretroviral Drug Resistance among HIV-1 Seroconverters in London, 1984–1991 by Easterbrook, P.J, Hertogs, K, Waters, A, Wills, B, Gazzard, B.G, Larder, B

“…Objectives: To examine the prevalence of resistance mutations and natural polymorphisms to reverse transcriptase (RT) and protease inhibitors in a cohort of…”
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Fate of Research Studies by Easterbrook, P J, Matthews, D R

“…A retrospective survey was conducted of 720 research protocols, approved by the Central Oxford Research Ethics Committee between 1984 and 1987, to determine…”
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