Search Results - "Eason, Isaac R"
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Water Accessibility Refinement of the Extended Structure of KirBac1.1 in the Closed State
Published in Frontiers in molecular biosciences (30-11-2021)“…NMR structures of membrane proteins are often hampered by poor chemical shift dispersion and internal dynamics which limit resolved distance restraints…”
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A Cholesterol Dimer Stabilizes the Inactivated State of an Inward‐Rectifier Potassium Channel
Published in Angewandte Chemie International Edition (21-03-2022)“…Cholesterol oligomers reside in multiple membrane protein X‐ray crystal structures. Yet, there is no direct link between these oligomers and a biological…”
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Cooperative Gating of a K+ Channel by Unmodified Biological Anionic Lipids Viewed by Solid-State NMR Spectroscopy
Published in Journal of the American Chemical Society (21-02-2024)“…Lipids adhere to membrane proteins to stimulate or suppress molecular and ionic transport and signal transduction. Yet, the molecular details of lipid–protein…”
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Growth phase-specific changes in the composition of E. coli transcription complexes
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-03-2019)“…In E. coli, a single oligomeric enzyme transcribes the genomic DNA, while multiple auxiliary proteins and regulatory RNA interact with the core RNA polymerase…”
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2H,13C‑Cholesterol for Dynamics and Structural Studies of Biological Membranes
Published in ACS omega (24-05-2022)“…We present a cost-effective means of 2H and 13C enrichment of cholesterol. This method exploits the metabolism of 2H,13C-acetate into acetyl-CoA, the first…”
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2 H, 13 C-Cholesterol for Dynamics and Structural Studies of Biological Membranes
Published in ACS omega (24-05-2022)“…We present a cost-effective means of H and C enrichment of cholesterol. This method exploits the metabolism of H, C-acetate into acetyl-CoA, the first…”
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Journal Article -
7
A Cholesterol Dimer Stabilizes the Inactivated State of an Inward‐Rectifier Potassium Channel
Published in Angewandte Chemie (21-03-2022)“…Cholesterol oligomers reside in multiple membrane protein X‐ray crystal structures. Yet, there is no direct link between these oligomers and a biological…”
Get full text
Journal Article