Search Results - "Eary, J F"

A Statistical Modeling Approach to the Analysis of Spatial Patterns of FDG-PET Uptake in Human Sarcoma by O'Sullivan, F., Wolsztynski, E., O'Sullivan, J., Richards, T., Conrad, E. U., Eary, J. F.

“…Clinical experience with positron emission tomography (PET) scanning of sarcoma, using fluorodeoxyglucose (FDG), has established spatial heterogeneity in the…”
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[18F]FMISO and [18F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression by RAJENDRAN, J. G, WILSON, D. C, KROHN, K. A, CONRAD, E. U, PETERSON, L. M, BRUCKNER, J. D, RASEY, J. S, CHIN, L. K, HOFSTRAND, P. D, GRIERSON, J. R, EARY, J. F

“…Hypoxia imparts resistance to radiotherapy and chemotherapy and also promotes a variety of changes in tumor biology through inducible promoters. The purpose of…”
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Follow-up of relapsed B-cell lymphoma patients treated with iodine-131-labeled anti-CD20 antibody and autologous stem-cell rescue by Liu, S Y, Eary, J F, Petersdorf, S H, Martin, P J, Maloney, D G, Appelbaum, F R, Matthews, D C, Bush, S A, Durack, L D, Fisher, D R, Gooley, T A, Bernstein, I D, Press, O W

“…Radioimmunotherapy (RIT) is a promising treatment approach for B-cell lymphomas. This is our first opportunity to report long-term follow-up data and late…”
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Carbon-11-Thymidine and FDG to Measure Therapy Response by Shields, Anthony F, Mankoff, David A, Link, Jeanne M, Graham, Michael M, Eary, Janet F, Kozawa, Susie M, Zheng, Minna, Lewellen, Barbara, Lewellen, Thomas K, Grierson, John R, Krohn, Kenneth A

“…This study was performed to determine if PET imaging with 11C-thymidine could measure tumor response to chemotherapy early after the initiation of treatment…”
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Quantitative [F-18]fluorodeoxyglucose positron emission tomography in pretreatment and grading of sarcoma by EARY, J. F, CONRAD, E. U, BRUCKNER, J. D, FOLPE, A, HUNT, K. J, MANKOFF, D. A, HOWLETT, A. T

“…The purpose of this study was to determine the relationship between sarcoma tumor grade and the quantitative tumor metabolism value for…”
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(F-18) Fluorodeoxyglucose Positron Emission Tomography as a Predictor of Pathologic Grade and Other Prognostic Variables in Bone and Soft Tissue Sarcoma by FOLPE, A. L, LYLES, R. H, SPROUSE, J. T, CONRAD, E. U, EARY, J. F

“…Positron emission tomography (PET) can be used to measure tumor metabolism in sarcomas by measuring the standard uptake value (SUV) of (F-18)…”
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Statistical assessment of treatment response in a cancer patient based on pre‐therapy and post‐therapy FDG‐PET scans by Wolsztynski, E., O'Sullivan, F., O'Sullivan, J., Eary, J. F.

“…This work arises from consideration of sarcoma patients in which fluorodeoxyglucose positron emission tomography (FDG‐PET) imaging pre‐therapy and…”
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Radiolabeled-Antibody Therapy of B-Cell Lymphoma with Autologous Bone Marrow Support by Press, Oliver W, Eary, Janet F, Appelbaum, Frederick R, Martin, Paul J, Badger, Christopher C, Nelp, Wil B, Glenn, Stephan, Butchko, Greg, Fisher, Darrell, Fisher, Lloyd D, Porter, Bruce, Matthews, Dana C, Bernstein, Irwin D

“…Treatment with anthracycline-based chemotherapy regimens results in complete remission in 50 to 90 percent of patients with intermediate and high-grade…”
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Nuclear medicine in cancer diagnosis by Eary, Janet F

“…Nuclear medicine imaging has contributed significantly to diagnosis, treatment planning, and the evaluation of response to treatment in patients with cancer…”
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Samarium-153-EDTMP in Bone Metastases of Hormone Refractory Prostate Carcinoma: A Phase I/II Trial by Collins, Carolyn, Eary, Janet F, Donaldson, Gary, Vernon, Cheryl, Bush, Nigel E, Petersdorf, Stephen, Livingston, Robert B, Gordon, Edwin E, Chapman, C. Richard, Appelbaum, Frederick R

“…Samarium-153-ethylenediaminetetramethylene phosphoric acid (EDTMP), a bone-seeking radiopharmaceutical, was given to prostate cancer patients in a dose…”
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2-[C-11]thymidine imaging of malignant brain tumors by EARY, J. F, MANKOFF, D. A, SPENCE, A. M, BERGER, M. S, OLSHEN, A, LINK, J. M, O'SULLIVAN, F, KROHN, K. A

“…Malignant brain tumors pose diagnostic and therapeutic problems. Despite the advent of new brain imaging modalities, including magnetic resonance imaging (MRI)…”
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Imaging guidelines for children with Ewing sarcoma and osteosarcoma: A report from the Children's Oncology Group Bone Tumor Committee by Meyer, James S., Nadel, Helen R., Marina, Neyssa, Womer, Richard B., Brown, Kenneth L. B., Eary, J.F., Gorlick, Richard, Grier, Holcombe E., Randall, R. Lor, Lawlor, Elizabeth R., Lessnick, Stephen L., Schomberg, Paula J., Kailo, Mark D.

“…The Children's Oncology Group (COG) is a multi‐institutional cooperative group dedicated to childhood cancer research that has helped to increase the survival…”
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Tumor Metabolic Rates in Sarcoma Using FDG PET by Eary, Janet F, Mankoff, David A

“…In a busy clinical environment, the arterial blood sampling and long imaging time used for the determination of tumor metabolic rates are not always feasible…”
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Kinetic Analysis of 2-[Carbon-11]Thymidine PET Imaging Studies: Compartmental Model and Mathematical Analysis by Mankoff, David A, Shields, Anthony F, Graham, Michael M, Link, Jeanne M, Eary, Janet F, Krohn, Kenneth A

“…Carbon-11-thymidine is a PET tracer of DNA synthesis and cellular proliferation. Quantitative analysis of [11C]thymidine images is complicated by the presence…”
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Kinetic Analysis of 2-[11C]Thymidine PET Imaging Studies: Validation Studies by Mankoff, David A, Shields, Anthony F, Link, Jeanne M, Graham, Michael M, Muzi, Mark, Peterson, Lanell M, Eary, Janet F, Krohn, Kenneth A

“…2-[11C]thymidine has been tested as a PET tracer of cellular proliferation. We have previously described a model of thymidine and labeled metabolite kinetics…”
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Treatment of refractory non-Hodgkin's lymphoma with radiolabeled MB-1 (anti-CD37) antibody by Press, O W, Eary, J F, Badger, C C, Martin, P J, Appelbaum, F R, Levy, R, Miller, R, Brown, S, Nelp, W B, Krohn, K A

“…The biodistribution, toxicity, and therapeutic potential of anti-CD37 monoclonal antibody (MoAb) MB-1 labeled with iodine 131 (131I) was evaluated in ten…”
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Samarium-153-EDTMP Biodistribution and Dosimetry Estimation by Eary, Janet F, Collins, Carolyn, Stabin, Michael, Vernon, Cheryl, Petersdorf, Steve, Baker, Melissa, Hartnett, Shelley, Ferency, Sandra, Addison, Stanley J, Appelbaum, Frederick, Gordon, Edwin E

“…Fifty-two patients were treated with single doses of 153Sm-EDTMP in a Phase I escalating dose protocol for palliation of bone pain from metastatic prostate…”
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Tumor heterogeneity measurement using [18F] FDG PET/CT shows prognostic value in patients with non-small cell lung cancer by Hughes, N. M., Mou, T., O’Regan, K. N., Murphy, P., O’Sullivan, J. N., Wolsztynski, E., Huang, J., Kennedy, M. P., Eary, J. F., O’Sullivan, F.

“…Background The aim of this study was to evaluate primary tumor heterogeneity in patients with FDG-avid non-small cell lung cancer on PET/CT, with a view to…”
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Imaging of oncologic patients: benefit of combined CT and FDG PET in the diagnosis of malignancy by Eubank, WB, Mankoff, DA, Schmiedl, UP, Winter, TC, 3rd, Fisher, ER, Olshen, AB, Graham, MM, Eary, JF

“…The purpose of this study was to assess the benefit of combined CT and 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in diagnosing…”
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The use of radiolabeled anti-CD33 antibody to augment marrow irradiation prior to marrow transplantation for acute myelogenous leukemia by Appelbaum, F R, Matthews, D C, Eary, J F, Badger, C C, Kellogg, M, Press, O W, Martin, P J, Fisher, D R, Nelp, W B, Thomas, E D

“…Disease recurrence remains a major limitation to the use of marrow transplantation to treat leukemia. Previous transplant studies have demonstrated that higher…”
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