Search Results - "Earp, Cody E"
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Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs
Published in Nature chemical biology (01-07-2023)“…Natural products research increasingly applies -omics technologies to guide molecular discovery. While the combined analysis of genomic and metabolomic…”
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A Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross‐Linked Cyclopeptides
Published in Angewandte Chemie International Edition (06-02-2023)“…Cyclopeptide alkaloids are an abundant class of plant cyclopeptides with over 200 analogs described and bioactivities ranging from analgesic to antiviral…”
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Wheldone Revisited: Structure Revision Via DFT-GIAO Chemical Shift Calculations, 1,1-HD-ADEQUATE NMR Spectroscopy, and X‑ray Crystallography Studies
Published in Journal of natural products (Washington, D.C.) (23-08-2024)“…Wheldone is a fungal metabolite isolated from the coculture of Aspergillus fischeri and Xylaria flabelliformis, displaying cytotoxic activity against breast,…”
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Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma -derived metabolite cues
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2023)“…Fungus-growing ants depend on a fungal mutualist that can fall prey to fungal pathogens. This mutualist is cultivated by these ants in structures called fungus…”
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Arenicolins: C‑Glycosylated Depsides from Penicillium arenicola
Published in Journal of natural products (Washington, D.C.) (27-03-2020)“…During investigation of the secondary metabolism of four strains of Penicillium arenicola, two new depsides, arenicolins A (1) and B (2), were isolated and…”
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Anti-cryptococcal activity of preussolides A and B, phosphoethanolamine-substituted 24-membered macrolides, and leptosin C from coprophilous isolates of Preussia typharum
Published in Journal of industrial microbiology & biotechnology (23-12-2021)“…Cryptococcus neoformans is a serious human pathogen with limited options for treatment. We have interrogated extracts from fungal fermentations to find…”
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Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae
Published in Journal of antibiotics (01-11-2023)“…As part of ongoing efforts to isolate biologically active fungal metabolites, a cyclic pentapeptide, sheptide A ( 1 ), was discovered from strain MSX53339 (…”
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Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster
Published in Metabolomics (02-08-2024)“…Introduction Fungi biosynthesize chemically diverse secondary metabolites with a wide range of biological activities. Natural product scientists have…”
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A Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side Chain Cross‐Linked Cyclopeptides
Published in Angewandte Chemie (06-02-2023)“…Cyclopeptide alkaloids are an abundant class of plant cyclopeptides with over 200 analogs described and bioactivities ranging from analgesic to antiviral…”
Get full text
Journal Article -
10
Studies on the hydrogen bond acidity, and other descriptors and properties for hydroxyflavones and hydroxyisoflavones
Published in Journal of molecular liquids (01-08-2015)“…An NMR method has been used to determine the hydrogen bond acidity, A, of a number of hydroxyisoflavones. Together with our previous studies on…”
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