Search Results - "EarL, A"
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STRUCTURE HARVESTER: a website and program for visualizing STRUCTURE output and implementing the Evanno method
Published in Conservation genetics resources (01-06-2012)“…We present STRUCTURE HARVESTER (available at http://taylor0.biology.ucla.edu/structureHarvester/ ), a web-based program for collating results generated by the…”
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Gut microbiota utilize immunoglobulin A for mucosal colonization
Published in Science (American Association for the Advancement of Science) (18-05-2018)“…The immune system responds vigorously to microbial infection while permitting lifelong colonization by the microbiome. Mechanisms that facilitate the…”
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Raman spectroscopy and machine learning for biomedical applications: Alzheimer’s disease diagnosis based on the analysis of cerebrospinal fluid
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-03-2021)“…[Display omitted] •Raman spectroscopy and machine learning is a universal tool for medical diagnosis.•Alzheimer’s disease is the most common form of dementia…”
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Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery
Published in Cell (16-06-2016)“…Recent advances in single-particle cryoelecton microscopy (cryo-EM) are enabling generation of numerous near-atomic resolution structures for well-ordered…”
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Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex
Published in Cell (05-10-2017)“…Prokaryotic cells possess CRISPR-mediated adaptive immune systems that protect them from foreign genetic elements, such as invading viruses. A central element…”
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Resolution advances in cryo-EM enable application to drug discovery
Published in Current opinion in structural biology (01-12-2016)“…•There is rapid growth in number of structures determined using cryo-EM methods.•Single particle cryo-EM can now achieve resolutions better than 2Å.•Drug…”
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Incidence and Early Course of Retinopathy of Prematurity
Published in Ophthalmology (Rochester, Minn.) (01-04-2020)“…In the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (ROP), 4099 infants weighing less than 1251 g at birth underwent sequential ophthalmic…”
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The Aerobic and Cognitive Exercise Study (ACES) for Community-Dwelling Older Adults With or At-Risk for Mild Cognitive Impairment (MCI): Neuropsychological, Neurobiological and Neuroimaging Outcomes of a Randomized Clinical Trial
Published in Frontiers in aging neuroscience (04-05-2018)“…Prior research has found that cognitive benefits of physical exercise and brain health in older adults may be enhanced when mental exercise is interactive…”
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Screening Examination of Premature Infants for Retinopathy of Prematurity
Published in Pediatrics (Evanston) (2013)“…This statement revises a previous statement on screening of preterm infants for retinopathy of prematurity (ROP) that was published in 2006. ROP is a…”
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Exergaming and older adult cognition: a cluster randomized clinical trial
Published in American journal of preventive medicine (01-02-2012)“…Dementia cases may reach 100 million by 2050. Interventions are sought to curb or prevent cognitive decline. Exercise yields cognitive benefits, but few older…”
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Raman spectroscopy of blood serum for Alzheimer's disease diagnostics: specificity relative to other types of dementia
Published in Journal of biophotonics (01-07-2015)“…The key moment for efficiently and accurately diagnosing dementia occurs during the early stages. This is particularly true for Alzheimer's disease (AD). In…”
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Seroprevalence of Brucella spp. and Rift Valley fever virus among slaughterhouse workers in Isiolo County, northern Kenya
Published in PLoS neglected tropical diseases (05-10-2023)“…Brucella spp. and Rift Valley fever virus (RVFV) are classified as priority zoonotic agents in Kenya, based on their public health and socioeconomic impact on…”
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A multi-hazard risk prioritisation framework for cultural heritage assets
Published in Natural hazards and earth system sciences (20-05-2020)“…Multi-hazard risk assessment of building portfolios is of primary importance in natural-hazard-prone regions, particularly for the prioritisation of disaster…”
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OrthoPhyl—streamlining large-scale, orthology-based phylogenomic studies of bacteria at broad evolutionary scales
Published in G3 : genes - genomes - genetics (07-08-2024)“…Abstract There are a staggering number of publicly available bacterial genome sequences (at writing, 2.0 million assemblies in NCBI's GenBank alone), and the…”
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A genome-wide perspective on the evolutionary history of enigmatic wolf-like canids
Published in Genome research (01-08-2011)“…High-throughput genotyping technologies developed for model species can potentially increase the resolution of demographic history and ancestry in wild…”
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N- and O-Glycans Modulate Galectin-1 Binding, CD45 Signaling, and T Cell Death
Published in The Journal of biological chemistry (22-01-2010)“…Galectin-1, a β-galactoside-binding protein highly expressed in the thymus, induces apoptosis of specific thymocyte subsets and activated T cells. Galectin-1…”
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Cryo‐electron microscopy – a primer for the non‐microscopist
Published in The FEBS journal (01-01-2013)“…Cryo‐electron microscopy (cryo‐EM) is increasingly becoming a mainstream technology for studying the architecture of cells, viruses and protein assemblies at…”
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High-field magnetic resonance imaging of brain iron: birth of a biomarker?
Published in NMR in biomedicine (01-11-2004)“…The brain has an unusually high concentration of iron, which is distributed in an unusual pattern unlike that in any other organ. The physiological role of…”
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Galectin multimerization and lattice formation are regulated by linker region structure
Published in Glycobiology (Oxford) (01-01-2011)“…Galectins regulate cellular functions by binding to glycan ligands on cell surface glycoprotein receptors. Prototype galectins, such as galectin-1, are one…”
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