Search Results - "Eames, Rhena"

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor by Maher, Toby M, Simpson, Juliet K, Porter, Joanna C, Wilson, Frederick J, Chan, Robert, Eames, Rhena, Cui, Yi, Siederer, Sarah, Parry, Simon, Kenny, Julia, Slack, Robert J, Sahota, Jagdeep, Paul, Lyn, Saunders, Peter, Molyneaux, Philip L, Lukey, Pauline T, Rizzo, Gaia, Searle, Graham E, Marshall, Richard P, Saleem, Azeem, Kang'ombe, Arthur R, Fairman, David, Fahy, William A, Vahdati-Bolouri, Mitra

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with poor prognosis and a significant unmet medical need. This study evaluated the…”
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Safety, Tolerability, and Pharmacokinetics of a New Formulation of Nemiralisib Administered via a Dry Powder Inhaler to Healthy Individuals by Wilson, Robert, Templeton, Alison, Leemereise, Claudia, Eames, Rhena, Banham-Hall, Edward, Hessel, Edith M., Cahn, Anthony

“…Nemiralisib, a phosphoinositide 3-kinase δ inhibitor, is being investigated as an immunomodulatory agent with anti-inflammatory properties in chronic…”
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A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled [alpha]v[beta]6 integrin inhibitor by Maher, Toby M, Simpson, Juliet K, Porter, Joanna C, Wilson, Frederick J, Chan, Robert, Eames, Rhena, Cui, Yi, Siederer, Sarah, Parry, Simon, Kenny, Julia, Slack, Robert J, Sahota, Jagdeep, Paul, Lyn, Saunders, Peter, Molyneaux, Philip L, Lukey, Pauline T, Rizzo, Gaia, Searle, Graham E, Marshall, Richard P, Saleem, Azeem, Kang'ombe, Arthur R, Fairman, David, Fahy, William A, Vahdati-Bolouri, Mitra

“…Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease with poor prognosis and a significant unmet medical need. This study…”
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Effects of Recombinant Human Angiotensin-Converting Enzyme 2 on Response to Acute Hypoxia and Exercise: A Randomised, Placebo-Controlled Study by Hall, David A., Hanrott, Kate, Badorrek, Philipp, Berliner, Dominik, Budd, David C., Eames, Rhena, Powley, William M., Hewens, Deborah, Siederer, Sarah, Lazaar, Aili L., Cahn, Anthony, Hohlfeld, Jens M.

“…Introduction Angiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin-angiotensin system (RAS) that has been implicated in the pathogenesis of acute…”
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