Search Results - "Eades, Gabriel"

miR-200a Regulates Nrf2 Activation by Targeting Keap1 mRNA in Breast Cancer Cells by Eades, Gabriel, Yang, Muhua, Yao, Yuan, Zhang, Yongshu, Zhou, Qun

“…NF-E2-related factor 2 (Nrf2) is an important transcription factor that activates the expression of cellular detoxifying enzymes. Nrf2 expression is largely…”
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lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6 by Eades, Gabriel, Wolfson, Benjamin, Zhang, Yongshu, Li, Qinglin, Yao, Yuan, Zhou, Qun

“…Triple-negative (ER(-), HER2(-), PR(-)) breast cancer (TNBC) is an aggressive disease with a poor prognosis with no available molecularly targeted therapy…”
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miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells by Eades, Gabriel, Yao, Yuan, Yang, Muhua, Zhang, Yongshu, Chumsri, Saranya, Zhou, Qun

“…Evidence supports a critical role for microRNAs (miRNAs) in regulation of tissue-specific differentiation and development. Signifying a disruption of these…”
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Characterization of a stem-like subpopulation in basal-like ductal carcinoma in situ (DCIS) lesions by Li, Qinglin, Eades, Gabriel, Yao, Yuan, Zhang, Yongshu, Zhou, Qun

“…Previously, we found that basal-like ductal carcinoma in situ (DCIS) contains cancer stem-like cells. Here, we characterize stem-like subpopulations in a model…”
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Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer by Gernapudi, Ramkishore, Yao, Yuan, Zhang, Yongshu, Wolfson, Benjamin, Roy, Sanchita, Duru, Nadire, Eades, Gabriel, Yang, Peixin, Zhou, Qun

“…The tumor microenvironment plays a critical role in regulating breast tumor progression. Signaling between preadipocytes and breast cancer cells has been found…”
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The Krüppel-like factor 2 and Krüppel-like factor 4 genes interact to maintain endothelial integrity in mouse embryonic vasculogenesis by Chiplunkar, Aditi R, Curtis, Benjamin C, Eades, Gabriel L, Kane, Megan S, Fox, Sean J, Haar, Jack L, Lloyd, Joyce A

“…Krüppel-like Factor 2 (KLF2) plays an important role in vessel maturation during embryonic development. In adult mice, KLF2 regulates expression of the tight…”
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MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism by Yang, Muhua, Yao, Yuan, Eades, Gabriel, Zhang, Yongshu, Zhou, Qun

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Long non-coding RNAs in stem cells and cancer by Eades, Gabriel

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Adipocyte activation of cancer stem cell signaling in breast cancer by Wolfson, Benjamin, Eades, Gabriel, Zhou, Qun

“…Signaling within the tumor microenvironment has a critical role in cancer initiation and progression. Adipocytes, one of the major components of the breast…”
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MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism by Yang, Muhua, Yao, Yuan, Eades, Gabriel, Zhang, Yongshu, Zhou, Qun

“…NF-E2-related factor 2 (Nrf2) is an important transcription factor involved in antioxidant response. Nrf2 binds antioxidant response elements (ARE) within…”
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Estrogen Receptor α Signaling Regulates Breast Tumor-initiating Cells by Down-regulating miR-140 Which Targets the Transcription Factor SOX2 by Zhang, Yongshu, Eades, Gabriel, Yao, Yuan, Li, Qinglin, Zhou, Qun

“…Several reports have indicated that miR-140, a possible tumor suppressor microRNA (miR), is down-regulated in breast tumors compared with normal breast…”
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An expanded universe of cancer targets by Hahn, William C., Bader, Joel S., Braun, Theodore P., Clemons, Paul A., Druker, Brian J., Fu, Haian, Kim, William, McManus, Michael T., B. Mills, Gordon, Mo, Xiulei, Sahni, Nidhi, Schreiber, Stuart L., Tamayo, Pablo, Tyner, Jeffrey W., Wagner, Bridget K., Weiss, William A., Dancik, Vlado, Gill, Shubhroz, Hua, Bruce, Sharifnia, Tanaz, Viswanathan, Vasanthi, Zou, Yilong, Dela Cruz, Filemon, Kung, Andrew, Stockwell, Brent, Boehm, Jesse, Manguso, Robert, Vazquez, Francisca, Du, Yuhong, Ivanov, Andrey, Moreno, Carlos S., Niu, Qiankun, Ramalingam, Suresh, Reyna, Matthew, Zhou, Wei, Grandori, Carla, Cai, Jitong, Chan, Issac S., Dunworth, Matthew, Ge, Yuchen, Grasset, Eloïse M., Knútsdóttir, Hildur, Lerner, Michael G., Padmanaban, Veena, Perrone, Matthew C., Suhail, Yasir, Tsehay, Yohannes, Warrier, Manisha, Morrow, Quin, Nechiporuk, Tamilla, Long, Nicola, Saultz, Jennifer, Kaempf, Andy, Minnier, Jessica, Tognon, Cristina E., Kurtz, Stephen E., Brown, Jordana, Watanabe-Smith, Kevin, Vu, Tania Q., Yan, Yunqi, Robinson, Bridget, Lind, Evan F., Kosaka, Yoko, Demir, Emek, Estabrook, Joseph, Grzadkowski, Michael, Nikolova, Olga, Deneen, Ben, Liang, Han, Bassik, Michael C., Bhattacharya, Asmita, Brennan, Kevin, Curtis, Christina, Ji, Hanlee P., Karlsson, Kasper A.J., Lo, Yuan-Hung, Liu, Katherine, Nakano, Michitaka, Smith, Amber R., Spees, Kaitlyn, Wong, Wing Hing, Yuki, Kanako, Hangauer, Matt, Kaufman, Dan S., Balmain, Allan, Chen, Wei-Ching, Fan, QiWen, Kersten, Kelly, Krummel, Matthew, Menard, Marie, Nasholm, Nicole, Schmidt, Christin, Serwas, Nina K., Yoda, Hiroyuki, Ashworth, Alan, Bandyopadhyay, Sourav, Bivona, Trevor, Eades, Gabriel, Oberlin, Stefan, Wang, Yuhao

“…The characterization of cancer genomes has provided insight into somatically altered genes across tumors, transformed our understanding of cancer biology, and…”
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Abstract 1463: Long non-coding RNA RoR and microRNA-145 regulate tumor cell invasion in triple-negative breast cancer via targeting of ADP-ribosylation factor 6 by Eades, Gabriel L., Zhou, Qun

“…Abstract Triple-negative (ER-, HER2-, PR-) breast cancer (TNBC) is an aggressive disease with a poor prognosis. Currently, there is no available molecularly…”
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Long non-coding RNAs in stem cells and cancer by Eades, Gabriel, Zhang, Yong-Shu, Li, Qing-Lin, Xia, Ji-Xiang, Yao, Yuan, Zhou, Qun

“…An overwhelming majority of the transcribed genome encodes for non-coding RNA (ncRNA) sequences. Deep sequencing of the transcriptome has uncovered tens of…”
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Examining estrogen regulation of cancer stem cells through multicolor lineage tracing by Zhang, Yongshu, Eades, Gabriel, Zhou, Qun

“…We have designed a dual-color fluorescent reporter that can track microRNA expression in vitro, which can be used for lineage tracing experiments. We have used…”
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Abstract 2302: Epigenetic activation of miR-200a targets the Nrf2-dependent chemoprevention pathway in breast cancer by Zhou, Qun, Yao, Yuan, Gabriel, Eades

“…Abstract NF-E2-related factor 2 (Nrf2) is an important transcription factor that activates the expression of cellular detoxifying enzymes. Nrf2 expression is…”
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Characterization of a Stem-like Subpopulation in Basal-like Ductal Carcinoma in Situ (DCIS) LesionsThis work was supported, in whole or in part, by grants from American Cancer Society and NCI, National Institutes of Health R01 CA163820 and R01 CA157779 (to Q. Z.) by Li, Qinglin, Eades, Gabriel, Yao, Yuan, Zhang, Yongshu, Zhou, Qun

“…Previously, we found that basal-like ductal carcinoma in situ (DCIS) contains cancer stem-like cells. Here, we characterize stem-like subpopulations in a model…”
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Abstract 107: miR-200a targets SIRT1 for malignant transformation by Eades, Gabriel, Yao, Yuan, Zhou, Qun

“…Abstract Evidence supports a critical role for microRNAs in regulation of tissue specific differentiation and development. Signifying a disruption of these…”
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Epigenetic Regulation of miRNAs and Breast Cancer Stem Cells by Duru, Nadire, Gernapudi, Ramkishore, Eades, Gabriel, Eckert, Richard, Zhou, Qun

“…MicroRNAs (miRNAs) have emerged as important targets of chemopreventive strategies in breast cancer. We have found that miRNAs are dysregulated at an early…”
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Abstract 3079: Estrogen signaling promotes cancer stem cell expansion via microRNA-140 targeting of pluripotency-associated factor SOX2 in ERα positive breast cancer cells by Zhang, Yongshu, Eades, Gabriel L., Yao, Yuan, Li, Qinglin, Zhou, Qun

“…Abstract Multiple reports indicate that the prospective tumor suppressor miR-140 is down regulated in breast tumors compared to normal breast tissues; however,…”
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