Search Results - "EZEKOWITZ, R. A. B"
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Phylogenetic Perspectives in Innate Immunity
Published in Science (American Association for the Advancement of Science) (21-05-1999)“…The concept of innate immunity refers to the first-line host defense that serves to limit infection in the early hours after exposure to microorganisms. Recent…”
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2
systems biology analysis of the Drosophila phagosome
Published in Nature (04-01-2007)“…Phagocytes have a critical function in remodelling tissues during embryogenesis and thereafter are central effectors of immune defence. During phagocytosis,…”
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3
Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor
Published in Nature (London) (09-05-1991)“…Human exposure to Pneumocystis carinii is common but, in the absence of acquired or genetic dysfunction of either cellular or humoral immunity, exposure rarely…”
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4
The Gly-54-->Asp allelic form of human mannose-binding protein (MBP) fails to bind MBP-associated serine protease
Published in Biochemical journal (01-11-1995)“…The human mannose-binding protein (MBP) is a pattern recognition molecule that appears to play a role in initial host defence. MBP activates the complement…”
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Distinct and overlapping functions of allelic forms of human mannose binding protein
Published in Nature genetics (01-09-1992)“…Human mannose binding protein (MBP) is a C-type serum lectin involved in first-line host defense against a variety of bacterial, fungal and viral pathogens…”
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Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin
Published in Journal of general virology (01-03-1994)“…1 Department of Microbiology, University of Melbourne, Parkville, Victoria 3052, Australia and 2 Division of Hematology/Oncology, Children's Hospital and…”
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7
Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes
Published in Mammalian genome (01-02-1995)“…Mannose-binding protein (MBP) is a member of a family of collagenous lectins (collectins), which are believed to play an important role in first-line host…”
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The structure and function of vertebrate mannose lectin-like proteins
Published in Journal of cell science (1988)“…Sugar-specific recognition is now well established as an important determinant of cell-cell interactions and host defence mechanisms. Macrophages, in…”
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9
Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila
Published in Science (American Association for the Advancement of Science) (18-06-1999)“…Macrophages in the Drosophila embryo are responsible for the phagocytosis of apoptotic cells and are competent to engulf bacteria. Croquemort (CRQ) is a…”
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10
Spastic diplegia as a complication of interferon Alfa-2a treatment of hemangiomas of infancy
Published in The Journal of pediatrics (01-03-1998)“…We report the development of spastic diplegia in infants during the course of interferon Alfa-2a (IFN) therapy for potentially life-endangering hemangiomas…”
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Interferon Alfa-2a Therapy for Life-Threatening Hemangiomas of Infancy
Published in The New England journal of medicine (28-05-1992)“…HEMANGIOMA of infancy is an angiomatous disorder characterized by the proliferation of capillary endothelium, with multilamination of the basement membrane 1 ,…”
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The murine mannose-binding protein genes (Mbl 1 and Mbl 2) localize to chromosomes 14 and 19
Published in Mammalian genome (01-12-1994)Get full text
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Cerebral vasculopathy and neurologic sequelae in infants with cervicofacial hemangioma: report of eight patients
Published in Radiology (01-06-1998)“…To determine the association of cerebral arterial anomalies and progressive cerebral arterial occlusive disease in infants with facial hemangiomas. The cases…”
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14
Molecular characterization of the human macrophage mannose receptor : demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in cos-1 cells
Published in The Journal of experimental medicine (01-12-1990)“…The macrophage mannose receptor is an integral membrane protein expressed on the surface of tissue macrophages. After ligation of mannose-rich glycoconjugates…”
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15
Hepatic vascular anomalies in infancy: A twenty-seven-year experience
Published in The Journal of pediatrics (01-09-1996)“…OBJECTIVE: Infantile hemangioma and arteriovenous malformation (AVM) of the liver have a similar presentation but a different natural history, and therefore…”
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The human mannose-binding protein functions as an opsonin
Published in The Journal of experimental medicine (01-05-1989)“…The human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains: a cysteine-rich NH2-terminal domain that stabilizes…”
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Monoclonal Antibodies to a Particulate Superoxide-Forming System Stimulate a Respiratory Burst in Intact Guinea Pig Neutrophils
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1986)“…Monoclonal rat antibodies were produced against a subcellular preparation of phorbol 12-myristate 13-acetate (PMA)-stimulated guinea pig neutrophils that…”
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Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype
Published in The Journal of immunology (1950) (01-09-2005)Get full text
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Successful treatment of infantile Hemangiomas with Interferon-α-2b
Published in Journal of pediatric hematology/oncology (01-05-1997)Get full text
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Association of familial deficiency of mannose-binding lectin and meningococcal disease
Published in The Lancet (British edition) (25-09-1999)“…We report the case of an 18-year-old man with meningococcal meningitis and low serum concentrations of mannose-binding lectin (MBL). His mother and…”
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