Search Results - "EVERS, S. G"

K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung by Westra, W H, Slebos, R J, Offerhaus, G J, Goodman, S N, Evers, S G, Kensler, T W, Askin, F B, Rodenhuis, S, Hruban, R H

“…Point mutations in codon 12 of the K-ras protooncogene occur more frequently in lung adenocarcinomas from smokers (30%) than they do in lung adenocarcinomas…”
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Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung by Rodenhuis, S, van de Wetering, M L, Mooi, W J, Evers, S G, van Zandwijk, N, Bos, J L

“…To define the role of cellular oncogenes in human cancers, we studied the prevalence of mutational activation of ras oncogenes in untreated non-small-cell lung…”
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Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung by RODENHUIS, S, SLEBOS, R. J. C, BOOT, A. J. M, EVERS, S. G, MOOI, W. J, WAGENAAR, S. S, VAN BODEGOM, P. C, BOS, J. L

“…47 tumor samples, 45 of which were obtained at thoracotomy for non-small cell lung cancer were examined for mutational activation of the oncogenes H-ras,…”
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Sex hormone receptors in mammary tumours of GR mice by Sluyser, Mels, Evers, S. G, De Goeij, C. C. J

“…Studies of the growth behaviour and hormone receptor contents of GR-mouse mammary tumours suggest that the hormone responsive tumours are mixed populations of…”
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Cellular protoonocogenes are infrequently amplified in untreated non-small cell lung cancer by SLEBOS, R. J. C, EVERS, S. G, WAGENAAR, S. S, RODENHUIS, S

“…To examine a potential contribution of protooncogene abnormalities other than point-mutational activation of the K-ras protooncogene in the classification of…”
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Allele-specific detection of K-ras oncogene expression in human non-small-cell lung carcinomas by Slebos, R J, Habets, G G, Evers, S G, Mooi, W J, Rodenhuis, S

“…Point mutations in codon 12 of the K-ras oncogene are frequent in human lung adenocarcinomas. To study the expression of the K-ras gene in these tumors we have…”
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Different int-1 region DNA rearrangements within different zones of a single mouse mammary tumor by Sluyser, M, Moncharmont, B, van der Valk, M A, de Goeij, C C, Evers, S G

“…Fragments were taken from separate parts of hormone-dependent (HD) primary GR mouse mammary tumors and serially transplanted in estrone plus progesterone…”
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Hormonal regulation of mouse mammary tumor growth by Sluyser, M, Moncharmont, B, Ramp, G, de Goeij, C C, Evers, S G

“…In view of reports that human breast cancer cells secrete growth factors that can replace estradiol in sustaining tumor growth [1], we have investigated…”
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Chemotherapy and hormonal therapy of mouse mammary tumors by Sluyser, M, Evers, S G, de Goeij, C C

“…Single Cisplatin (Platinol) injections i.p. at 10 mg/kg dose level (LD10) caused a marked growth inhibition of both hormone dependent and independent GR mouse…”
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Combined endocrine therapy and chemotherapy of mouse mammary tumors by Sluyser, M, de Goeij, C C, Evers, S G

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Binding of 5S estradiol receptor to poly-deoxynucleotides by Sluyser, M, Evers, S G, Nijssen, T

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Changes in sensitivity to cyclophosphamide of mouse mammary tumors during serial transplantation by Sluyser, M, De Goeij, C C, Evers, S G

“…The effect of the cytostatic agent cyclophosphamide on the growth of several transplant generations of a GRS/A mouse mammary tumor line was studied…”
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Outgrowth of grafts containing different ratios of hormone-dependent and independent mouse mammary tumor cells by Sluyser, M, De Goeij, K C, Evers, S G

“…The growth properties of grafts composed of different mixtures of hormone-dependent and independent GR mouse mammary tumor cells were investigated. Grafts…”
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Effect of monohydroxytamoxifen on mouse mammary tumors by Sluyser, M, Evers, S G, de Goeij, C C

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A rapid and simple procedure for the routine detection of ras point mutations in formalin-fixed, paraffin-embedded tissues by Slebos, R J, Boerrigter, L, Evers, S G, Wisman, P, Mooi, W J, Rodenhuis, S

“…The use of the polymerase chain reaction (PCR) to detect specific DNA sequences in small amounts of tissues or cells has become a widespread tool in the field…”
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