Search Results - "ESTEVES, M. I"
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Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease
Published in Neuroscience (14-06-2017)“…Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits…”
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2
Effect of Protein Flexibility from Coarse-Grained Elastic Network Parameterizations on the Calculation of Free Energy Profiles of Ligand Binding
Published in Journal of chemical theory and computation (14-07-2020)“…The characterization of the affinity and binding mechanism of specific molecules to a protein active site is scientifically and industrially relevant for many…”
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3
Spiro-Lactams as Novel Antimicrobial Agents
Published in Current topics in medicinal chemistry (01-01-2020)“…Structural modulation of previously identified lead spiro-β-lactams with antimicrobial activity was carried out. The main objective of this work was to…”
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4
Large unilamellar vesicles as trehalose-stabilised vehicles for vaccines: storage time and in vivo studies
Published in Journal of controlled release (03-07-2000)“…Liposomes, as a pharmaceutical formulation must display a long shelf life. The recombinant heat-shock protein from Mycobacterium leprae (18-kDa hsp) or its…”
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5
Helicobacter pylori Gastritis in Cats with Long-Term Natural Infection as a Model of Human Disease
Published in The American journal of pathology (01-02-2000)“…A natural infection with Helicobacter pylori(H. pylori) in domestic cats ( Felis cattus) less than 2 years of age has been well described in a closed colony of…”
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6
Effect of isoflurane on hematologic variables in ferrets
Published in American journal of veterinary research (01-10-1994)“…Effects of isoflurane on the CBC in ferrets were studied. There was rapid decrease in all hematologic variables after induction of anesthesia. Percentage…”
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7
Spontaneous leprosy in a wild-caught cynomolgus macaque
Published in International journal of leprosy and other mycobacterial diseases (01-06-1998)“…Naturally occurring Mycobacterium leprae has been previously documented in only two species of nonhuman primates from West Africa--the chimpanzee and the sooty…”
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8
A technique for catheterization of the urinary bladder in the ferret
Published in Laboratory animals (London) (01-04-1994)“…The technique of catheterization of the urinary bladder, an important clinical skill for the diagnosis of urinary tract disorders, has not been described for…”
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9
Estimation of glomerular filtration rate and evaluation of renal function in ferrets (Mustela putorius furo)
Published in American journal of veterinary research (01-01-1994)“…Three methods of determining glomerular filtration rate (GFR) were performed in adult ferrets, 9 months to 7 years old. Endogenous creatinine clearance was…”
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10
Isolation and characterization of a thrombin-like enzyme from the venom of Crotalus durissus terrificus
Published in Brazilian journal of medical and biological research (1986)“…A thrombin-like enzyme was isolated in 6% yield from the venom of Crotalus durissus terrificus by ammonium sulfate precipitation followed by gel filtration on…”
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11
Stabilisation of immunoconjugates by trehalose
Published in Biotechnology letters (01-03-2000)“…Stable immunoconjugates were prepared in the presence of 400 mM trehalose. Their residual activity after freeze-drying, rehydration and incubation for 9 h at…”
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12
Helicobacter pylori Infection in the Cat: Evaluation of Gastric Colonization, Inflammation and Function
Published in Helicobacter (Cambridge, Mass.) (01-03-2001)“…Background. Further elucidation of the consequences of Helicobacter pylori infection on gastric mucosal inflammation and gastric secretory function would be…”
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13
Distribution of technetium 99m-labeled red blood cells during isoflurane anesthesia in ferrets
Published in American journal of veterinary research (01-07-1997)“…To address the physiologic mechanism of isoflurane-associated reduction in hematologic variables in ferrets. 6 young adult female ferrets. Distribution of…”
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