Search Results - "ESSELTINE, Dixie L"
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Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma
Published in The New England journal of medicine (28-08-2008)“…Patients with newly diagnosed multiple myeloma who were ineligible for treatment with high-dose chemotherapy plus hematopoietic stem-cell transplantation were…”
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Bortezomib Plus Melphalan and Prednisone Compared With Melphalan and Prednisone in Previously Untreated Multiple Myeloma: Updated Follow-Up and Impact of Subsequent Therapy in the Phase III VISTA Trial
Published in Journal of clinical oncology (01-05-2010)“…The purpose of this study was to confirm overall survival (OS) and other clinical benefits with bortezomib, melphalan, and prednisone (VMP) versus melphalan…”
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Primary Therapy of Waldenström Macroglobulinemia With Bortezomib, Dexamethasone, and Rituximab: WMCTG Clinical Trial 05-180
Published in Journal of clinical oncology (10-08-2009)“…We examined the activity of bortezomib, dexamethasone, and rituximab (BDR) in patients with symptomatic, untreated Waldenström macroglobulinemia (WM). A cycle…”
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Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma
Published in The New England journal of medicine (16-06-2005)“…Bortezomib, an inhibitor of proteasomes (sites of protein degradation in cells), has activity against advanced multiple myeloma. This study compared bortezomib…”
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Bortezomib in recurrent and/or refractory multiple myeloma: Initial clinical experience in patients with impaired renal function
Published in Cancer (15-03-2005)Get full text
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Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma with less than optimal response to bortezomib alone
Published in Haematologica (Roma) (01-07-2006)“…St. Vincent's Comprehensive Cancer Center, 325 West 15th Street, New York, NY, USA. sjagannath@aptiumoncology.com BACKGROUND AND OBJECTIVEs: The efficacy and…”
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Safety of prolonged therapy with bortezomib in relapsed or refractory multiple myeloma
Published in Cancer (15-11-2005)“…BACKGROUND Bortezomib, a first‐in‐class proteasome inhibitor, is active with manageable toxicities in relapsed and/or refractory myeloma. METHODS Bortezomib…”
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Bortezomib in recurrent and/or refractory multiple myeloma
Published in Cancer (15-03-2005)“…BACKGROUND Bortezomib is a potent, reversible proteasome inhibitor that has been approved for the treatment of recurrent and/or refractory multiple myeloma,…”
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The Anti-Myeloma Effect of Bortezomib Is Associated with Osteoblastic Activity
Published in Blood (16-11-2005)“…Myeloma bone disease is characterized by osteolytic destruction associated with suppressed osteoblastic activity possibly through inhibition of the WNT…”
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Bortezomib in recurrent and/or refractory multiple myeloma. Initial clinical experience in patients with impared renal function
Published in Cancer (15-03-2005)“…Bortezomib is a potent, reversible proteasome inhibitor that has been approved for the treatment of recurrent and/or refractory multiple myeloma, but its…”
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