Search Results - "ESQUENAZI, Eduardo"
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Molecular Networking As a Drug Discovery, Drug Metabolism, and Precision Medicine Strategy
Published in Trends in pharmacological sciences (Regular ed.) (01-02-2017)“…Molecular networking is a tandem mass spectrometry (MS/MS) data organizational approach that has been recently introduced in the drug discovery, metabolomics,…”
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2
Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle
Published in Proceedings of the National Academy of Sciences - PNAS (06-01-2015)“…The candidate phylum TM7 is globally distributed and often associated with human inflammatory mucosal diseases. Despite its prevalence, the TM7 phylum remains…”
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3
Mechanism insight into esterification of levulinic acid with methanol on H-Beta Zeolite: A DFT study
Published in Catalysis today (01-02-2025)“…The esterification of levulinic acid (LA) to alkyl levulinate esters from biomass by heterogeneous acid catalysis is a potential chemical route for the…”
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4
Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat
Published in mBio (05-02-2019)“…The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors,…”
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5
Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages
Published in Proceedings of the National Academy of Sciences - PNAS (25-03-2008)“…In all probability, natural selection began as ancient marine microorganisms were required to compete for limited resources. These pressures resulted in the…”
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6
Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage
Published in PloS one (12-04-2011)“…Filamentous marine cyanobacteria are extraordinarily rich sources of structurally novel, biomedically relevant natural products. To understand their…”
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7
Imaging mass spectrometry of natural products
Published in Natural product reports (01-01-2009)“…This Highlight article describes three different imaging mass spectrometry (IMS) approaches, MALDI, DESI and SIMS and their recent applications in the analysis…”
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8
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2011)“…Filamentous cyanobacteria of the genus Lyngbya are important contributors to coral reef ecosystems, occasionally forming dominant cover and impacting the…”
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Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya
Published in Environmental microbiology (01-06-2011)“…Marine cyanobacteria are prolific producers of bioactive secondary metabolites responsible for harmful algal blooms as well as rich sources of promising…”
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10
Characterization of the Bacterial Community of the Chemically Defended Hawaiian Sacoglossan Elysia rufescens
Published in Applied and Environmental Microbiology (01-11-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses
Published in Applied and Environmental Microbiology (01-06-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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12
Probing marine natural product defenses with DESI-imaging mass spectrometry
Published in Proceedings of the National Academy of Sciences - PNAS (05-05-2009)Get full text
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13
Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging
Published in Molecular bioSystems (01-01-2008)“…Marine cyanobacteria and sponges are prolific sources of natural products with therapeutic applications. In this paper we introduce a mass spectrometry based…”
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14
Temporal dynamics of natural product biosynthesis in marine cyanobacteria
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…Sessile marine organisms are prolific sources of biologically active natural products. However, these compounds are often found in highly variable amounts,…”
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15
Evidence for Ectopic Neurotransmission at a Neuronal Synapse
Published in Science (American Association for the Advancement of Science) (15-07-2005)“…Neurotransmitter release is well known to occur at specialized synaptic regions that include presynaptic active zones and postsynaptic densities. At…”
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16
Phylogeny-Guided Isolation of Ethyl Tumonoate A from the Marine Cyanobacterium cf. Oscillatoria margaritifera
Published in Journal of natural products (Washington, D.C.) (26-08-2011)“…The evolutionary relationships of cyanobacteria, as inferred by their SSU (16S) rRNA genes, were used as predictors of their potential to produce varied…”
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51437 Development of GB00408 and GB00499 as Novel Therapeutic Aryl Hydrocarbon Receptor Modulating Agents
Published in Journal of the American Academy of Dermatology (01-09-2024)Get full text
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18
Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase
Published in Bioorganic & medicinal chemistry letters (01-01-2025)“…[Display omitted] •A pathway-targeted cell-based screen identifies Cladophorol-A as a cGAS inhibitor.•Non-cytotoxic concentrations of Cladophorol-A inhibits…”
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A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens
Published in Journal of natural products (Washington, D.C.) (26-05-2017)“…Genome sequencing of microorganisms has revealed a greatly increased capacity for natural products biosynthesis than was previously recognized from compound…”
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Palmyramide A, a Cyclic Depsipeptide from a Palmyra Atoll Collection of the Marine Cyanobacterium Lyngbya majuscula
Published in Journal of natural products (Washington, D.C.) (26-03-2010)“…Bioassay-guided fractionation of the extract of a consortium of a marine cyanobacterium and a red alga (Rhodophyta) led to the discovery of a novel compound,…”
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