Search Results - "ESPINOSA, VERONICA PAEZ"

Lenvatinib-Loaded Poly(lactic-co-glycolic acid) Nanoparticles with Epidermal Growth Factor Receptor Antibody Conjugation as a Preclinical Approach to Therapeutically Improve Thyroid Cancer with Aggressive Behavior by Revilla, Giovanna, Al Qtaish, Nuseibah, Caruana, Pablo, Sainz-Ramos, Myriam, Lopez-Mendez, Tania, Rodriguez, Francisco, Paez-Espinosa, Verónica, Li, Changda, Vallverdú, Núria Fucui, Edwards, Maria, Moral, Antonio, Pérez, José Ignacio, Escolà-Gil, Juan Carlos, Pedraz, José Luis, Gallego, Idoia, Corcoy, Rosa, Céspedes, María Virtudes, Puras, Gustavo, Mato, Eugènia

“…Lenvatinib, a tyrosine kinase inhibitor (TKI) approved for the treatment of progressive and radioactive iodine (RAI)-refractory differentiated thyroid cancer…”
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Thyroid Hormones Selectively Regulate the Posttranslational Processing of Prothyrotropin-Releasing Hormone in the Paraventricular Nucleus of the Hypothalamus by Perello, Mario, Friedman, Theodore, Paez-Espinosa, Veronica, Shen, Xiaoxiong, Stuart, Ronald C, Nillni, Eduardo A

“…Over the last few years, our laboratory has demonstrated that different physiological conditions or stressors affect the posttranslational processing of…”
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Cellular colocalization and coregulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism by Espinosa, Veronica Paez, Ferrini, Monica, Shen, Xiaoxiong, Lutfy, Kabirullah, Nillni, Eduardo A, Friedman, Theodore C

“…The prohormone convertases (PCs), PC1/3 and PC2, are involved in the tissue-specific endoproteolytic posttranslational processing of many hormonal precursors…”
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Effects of an antioxidants cocktail on glucose metabolism at rest, during exercise, and during a glucose load in healthy young subjects by Rodríguez, Ivan, Paez Espinosa, Enma Verónica, Zbinden-Foncea, Hermann, Echeverría, Francisca, Castro-Sepúlveda, Mauricio

“…ABSTRACT Background: Reactive oxygen species (ROS) regulate glucose metabolism (GM) in skeletal muscle by improving the translocation of GLUT4. Antioxidant…”
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Regulation of Cardiac Jak‐2 in Animal Models of Insulin Resistance by Rojas, Fernanda Alvarez, Carvalho, Carla R. O., Paez‐Espinosa, Veronica, Saad, Mario J. A.

“…Insulin induces phosphorylation and activation of JAK2 tyrosine, as well as its association with STAT1 and SHP2 in insulinsensitive tissues of intact rats,…”
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The 5‐HT 2A Receptor Antagonists Pizotifen and Cyproheptadine Inhibit Serotonin‐enhanced Platelet Function by Lin, Olivia, Espinosa, Enma Veronica Paez, Khasawneh, Fadi T

“…Abstract only In an effort to define new agents for antithrombotic purposes, there is an interest in repurposing FDA‐approved drugs as antiplatelet agents. The…”
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The C-terminal segment of the second extracellular loop of the thromboxane A 2 receptor plays an important role in platelet aggregation by Murad, John P., Espinosa, Enma Veronica Paez, Ting, Harold J., Khasawneh, Fadi T.

“…There is considerable interest in discovering novel antiplatelet approaches with an enhanced safety profile. To this end, in our efforts to define new targets…”
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DIFFERENTIAL REGULATION OF PC1/3, PC2 AND PHOSPHORYLATED CREB BY SHORT-TERM AND LONG-TERM MORPHINE TREATMENT: IMPLICATIONS FOR UNDERSTANDING THE “SWITCH” TO OPIATE ADDICTION by ESPINOSA, VERONICA PAEZ, LIU, YANJUN, FERRINI, MONICA, ANGHEL, ADRIAN, NIE, YING, TRIPATHI, PINKY V., PORCHE, RENE, JANSEN, ERIK, STUART, RONALD C., NILLNI, EDUARDO A., LUTFY, KABIRULLAH, FRIEDMAN, THEODORE C.

“…Drug addiction is a state of altered brain reward and self-regulation mediated by both neurotransmitter and hormonal systems. Although an organism’s internal…”
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A Novel Antithrombotic Agent Targeting the Human Thromboxane A 2 Receptor by Murad, John P, Espinosa, Enma Veronica Paez, Ting, Harold J, McClure, Diane, Khasawneh, Fadi T

“…Abstract only In efforts to define new targets for antithrombotic purposes, there is interest in utilizing antibodies targeting ligand binding domains of…”
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Transient Receptor Potential Channel 6: Role in Hemostasis and Thrombogenesis by Espinosa, Enma Veronica Paez, Murad, John P, Ting, Harold J, Khasawneh, Fadi T

“…Abstract only Although the importance of cytosolic calcium (Ca 2+ ) elevation in the regulation of platelet activation has been widely acknowledged, the…”
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A novel antibody targeting the ligand binding domain of the thromboxane A2 receptor exhibits antithrombotic properties in vivo by Murad, John P., Espinosa, Enma Veronica Paez, Ting, Harold J., McClure, Diane, Khasawneh, Fadi T.

“…► C-EL2Ab exhibits thromboxane A2 receptor-specific antiplatelet activity, ex vivo. ► C-EL2Ab protects against the development of occlusive thrombotic…”
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The C-terminal segment of the second extracellular loop of the thromboxane A2 receptor plays an important role in platelet aggregation by MURAD, John P, ESPINOSA, Enma Veronica Paez, TING, Harold J, KHASAWNEH, Fadi T

“…There is considerable interest in discovering novel antiplatelet approaches with an enhanced safety profile. To this end, in our efforts to define new targets…”
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Interleukin-1β Regulates Phospholipase D-1 Expression in Rat Pancreatic β-Cells by Chen, Meng-Chi, Paez-Espinosa, Veronica, Welsh, Nils, Eizirik, Décio L.

“…Abstract The cytokine interleukin (IL)-1β induces a biphasic effect in rat pancreatic islets, with an early and transitory stimulation of insulin release…”
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Interleukin-1β Regulates Phospholipase D-1 Expression in Rat Pancreatic β-Cells1 by Chen, Meng-Chi, Paez-Espinosa, Veronica, Welsh, Nils, Eizirik, Décio L

“…The cytokine interleukin (IL)-1β induces a biphasic effect in rat pancreatic islets, with an early and transitory stimulation of insulin release followed by…”
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Regulation of insulin-stimulated tyrosine phosphorylation of Shc and Shc/Grb2 association in liver, muscle, and adipose tissue of epinephrine- and streptozotocin-treated rats by Páez-Espinosa, V, Rocha, E M, Velloso, L A, Saad, M J

“…Shc protein phosphorylation has been extensively characterized as the initial step that activates a complex mitogenic pathway through its association with…”
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Insulin induces tyrosine phosphorylation of Shc and stimulates Shc/GRB2 association in insulin-sensitive tissues of the intact rat by Páez-Espinosa, V, Carvalho, C R, Alvarez-Rojas, F, Janeri, L, Velloso, L A, Boschero, A C, Saad, M J

“…Shc is a novel type of tyrosine-phosphorylated protein activated in response to a wide variety of polypeptide ligands. In this study, we used…”
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Insulin-induced tyrosine phosphorylation of Shc in liver, muscle and adipose tissue of insulin resistant rats by Páez-Espinosa, E.Verónica, Rocha, Eduardo M, Velloso, Lı́cio A, Boschero, Antonio C, Saad, Mário J.A

“…Insulin stimulates rapid tyrosine phosphorylation of the protein Shc, which subsequently binds to Grb2, resulting in the activation of a complex mitogenic…”
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