Search Results - "ESHIMA, K."

65 TAS-114 Enhances S-1 Activity in Vivo When Used in Combination by Yokogawa, T, Wakasa, T, Yano, W, Yoshisue, K, Fujioka, A, Eshima, K, Fukuoka, M, Matsuo, K, Noguchi, K, Utsugi, T

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Low-Dose Edoxaban in Very Elderly Patients with Atrial Fibrillation by Okumura, Ken, Akao, Masaharu, Yoshida, Tetsuro, Kawata, Masahito, Okazaki, Osamu, Akashi, Shintaro, Eshima, Kenichi, Tanizawa, Kimihiko, Fukuzawa, Masayuki, Hayashi, Takuya, Akishita, Masahiro, Lip, Gregory Y.H, Yamashita, Takeshi

“…Elderly patients with atrial fibrillation who were not appropriate candidates for standard doses of oral anticoagulants because of a high risk of bleeding were…”
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D110 CELLULAR AND MOLECULAR INVESTIGATIONS IN THORACIC ONCOLOGY: Microsomal Prostaglandin E Synthase-1 Promotes Lung Metastasis By Enhancement Of Accumulation Of Mdscs From Bone Marrow by Takahashi, R, Amano, H, Eshima, K, Shizuo, A, Majima, M

“…Material and methods Murine prostate cancer cells (RM9) were intravenously injected to Wild type mice (WT) and mPGES-1 knockout mice (mPGES-1 KO). The number…”
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A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin‐dependent diabetes mellitus in the non‐obese diabetic mouse by Eshima, Koji, Mora, Conchi, Wong, F. Susan, Green, E. Allison, Grewal, Iqbal S., Flavell, Richard A.

“…Although the critical requirement of CD4 T cells in type I (insulin‐dependent) diabetes mellitus (T1DM) has been well documented, information on the exact…”
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Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice by Nishizawa, Nobuyuki, Ito, Yoshiya, Eshima, Koji, Ohkubo, Hirotoki, Kojo, Ken, Inoue, Tomoyoshi, Raouf, Joan, Jakobsson, Per-Johan, Uematsu, Satoshi, Akira, Shizuo, Narumiya, Shuh, Watanabe, Masahiko, Majima, Masataka

“…[Display omitted] •mPGES-1/PGE2/EP4 pathway is enhanced during hepatic I/R.•Recruitment of mPGES-1+Ly6Chigh -macrophages delays liver repair.•EP4 signaling…”
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Generation of a mouse model of familial Parkinson’s disease bearing patient iPSC-derived transplanted neurospheres by Obinata, Y., Iwashita, Y., Nagai, M., Hattori, A., Eshima, K., Obata, F., Okano, H., Ohta, E.

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Microsomal prostaglandin E synthase-1 promotes lung metastasis via SDF-1/CXCR4-mediated recruitment of CD11b+Gr1+MDSCs from bone marrow by Takahashi, Ryo, Amano, Hideki, Ito, Yoshiya, Eshima, Koji, Satoh, Takefumi, Iwamura, Masatsugu, Nakamura, Masaki, Kitasato, Hidero, Uematsu, Satoshi, Raouf, Joan, Jakobsson, Per-Johan, Akira, Shizuo, Majima, Masataka

“…[Display omitted] Accumulation of myeloid-derived suppressor cells (MDSCs) to tumors is related to cancer prognosis. We investigated the contribution of host…”
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A80-C MOLECULAR AND IMMUNOBIOLOGY OF LUNG CANCER: Microsomal Prostaglandin E Synthase-1 (mpges-1) Facilitates Mobilization Of Mdsc From Bone Marrow And Induces Lung Metastasis Formation by Takahashi, R, Amano, H, Eshima, K, Satoh, T, Akira, S, Majima, M

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Rivaroxaban Monotherapy in Patients With Atrial Fibrillation After Coronary Stenting: Insights From the AFIRE Trial by Matoba, Tetsuya, Yasuda, Satoshi, Kaikita, Koichi, Akao, Masaharu, Ako, Junya, Nakamura, Masato, Miyauchi, Katsumi, Hagiwara, Nobuhisa, Kimura, Kazuo, Hirayama, Atsushi, Matsui, Kunihiko, Ogawa, Hisao

“…The aim of this AFIRE (Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease) trial subgroup analysis was to…”
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A110 THORACIC CANCERS: PATHOGENESIS AND NOVEL TARGETS: Microsomal Prostaglandin E Synthase-1 Enhances Lung Metastasis Formation By Accumulating Mdscs by Takahashi, R, Amano, H, Eshima, K, Satoh, T, Shizuo, A, Majima, M

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Stimulatory Effect of Endothelin-1 on Neurons in the Nucleus Tractus Solitarii Is Mediated by Non-N-Methyl-D-Aspartate Receptors by SHIHARA, Miwako, HIROOKA, Yoshitaka, ESHIMA, Kenichi, HORI, Nobuaki, TAKESHITA, Akira

“…We previously demonstrated that endothlin-1 (ET-1) augments and ETA receptor antagonist attenuates excitatory neuronal response to glutamate (Glu) in brainstem…”
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Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model by Iizuka, Kenzo, Jin, Cheng, Eshima, Kokoro, Hong, Mei Hua, Eshima, Kiyoshi, Fukushima, Masakazu

“…Peritoneal disseminated ovarian cancer is one of the most difficult cancers to treat with conventional anti-cancer drugs and the treatment options are very…”
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Derivation of T‐cell receptor α‐chain double expresser lines from normal murine mature T cells by ESHIMA, K., SUZUKI, H., YAMAZAKI, S., SHINOHARA, N.

“…Because the T‐cell receptor (TCR) α‐chain locus is known to lack allelic exclusion of rearrangements, and as a recent report revealed the existence of α‐chain…”
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D18 OLD DOG, NEW TRICKS: ADVANCES IN LUNG CANCER BIOLOGY: Dendritic Cells Secreting Sdf-1 And Tgf-[Beta] Via Cox-2 Derived Pge2-Ep3 Signaling Induce Pre-Metastatic Niche Formation In Mediastinal Lymph Node On Lung Cancer by Ogawa, F, Amano, H, Eshima, K, Hosono, K, Satoh, Y, Narumiya, S, Kumagai, Y, Majima, M

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Rivaroxaban Monotherapy in Patients With Atrial Fibrillation After Coronary Stenting by Matoba, Tetsuya, Yasuda, Satoshi, Kaikita, Koichi, Akao, Masaharu, Ako, Junya, Nakamura, Masato, Miyauchi, Katsumi, Hagiwara, Nobuhisa, Kimura, Kazuo, Hirayama, Atsushi, Matsui, Kunihiko, Ogawa, Hisao, Koretsune, Yukihiro, Hiro, Takafumi, Sumiyoshi, Tetsuya, Kimura, Kazumi, Hashimoto, Yoichiro, Hirano, Teruyuki, Daida, Hiroyuki, Okada, Yasushi, Yamazaki, Tsutomu, Nakamura, A., Tamiya, E., Yamamoto, T., Suetake, S., Noguchi, T., Nakamura, S., Matsumura, A., Kojima, J., Suwa, S., Yamaguchi, H., Kaikita, K., Yasu, T., Nakajima, A., Yamada, T., Arai, H., Hata, Y., Sakanashi, T., Tateishi, H., Nakayama, T., Nozaki, Y., Akao, M., Okumura, Y., Tokue, M., Kuroki, N., Maruyama, Y., Matoba, T., Hagiwara, N., Suzuki, H., Nishida, Y., Ajioka, M., Yumoto, K., Shimizu, S., Aoyama, T., Shimomura, H., Takeda, T., Oshiro, K., Sugishita, N., Shibata, Y., Otonari, T., Kihara, H., Ogawa, H., Ohno, A., Hazama, M., Shimizu, M., Tsukahara, K., Haruta, S., Wakeyama, T., Haruna, T., Ito, M., Fujii, K., Atsuchi, N., Sata, M., Kimura, K., Hasebe, N., Kobayasi, Y., Ohsato, K., Hironaga, K., Naganuma, Y., Anzaki, K., Oiwa, K., Okazaki, S., Nakagawa, Y., Tokuhiro, K., Tanaka, K., Momose, T., Fukushima, Y., Kametani, R., Kawamitsu, K., Saito, Y., Akashi, S., Kumagai, K., Eshima, K., Tobaru, T., Seo, T., Okuhara, K., Kozuma, K., Ikari, Y., Takahashi, T., Michishita, I.

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Feasibility of total intravenous anesthesia by cardiologists with the support of anesthesiologists during catheter ablation of atrial fibrillation by Yamaguchi, Takanori, Shimakawa, Yusuke, Mitsumizo, Shinji, Fukui, Akira, Kawano, Yuki, Otsubo, Toyokazu, Takahashi, Yuya, Hirota, Kei, Tsuchiya, Takeshi, Eshima, Kenichi

“…•Total intravenous anesthesia by cardiologists for atrial fibrillation ablation may be feasible.•No major anesthesia-related complications were…”
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Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents by Fukushima, Masakazu, Iizuka, Kenzo, Jin, Cheng, Zhang, Chun, Hong, Mei, Eshima, Kiyoshi

“…To reduce 5-fluorouracil (5-FU)-induced serious toxicities without loss of antitumor activity, we have developed DFP-11207, a novel fluoropyrimidine, which…”
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Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin) by Masumoto, Akihiro, Hirooka, Yoshitaka, Hironaga, Kiyoshi, Eshima, Kenichi, Setoguchi, Soko, Egashira, Kensuke, Takeshita, Akira

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Cross-Positive Selection of Thymocytes Expressing a Single TCR by Multiple Major Histocompatibility Complex Molecules of Both Classes: Implications for CD4+ versus CD8+ Lineage Commitment by Eshima, Koji, Suzuki, Harumi, Shinohara, Nobukata

“…This study has investigated the cross-reactivity upon thymic selection of thymocytes expressing transgenic TCR derived from a murine CD8+ CTL clone. The…”
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Thoughts at a hospital bed by Eshima, K

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