Search Results - "ERTRACHT, Offir"
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The mitochondria as a target for cardioprotection in acute myocardial ischemia
Published in Pharmacology & therapeutics (Oxford) (01-04-2014)“…The ischemic heart suffers from nutrient deprivation, lack of oxygen, metabolic acidosis, hyperkalemia and Ca(2+) overload as well as high level of reactive…”
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The impact of empagliflozin on cardiac physiology and fibrosis early after myocardial infarction in non-diabetic rats
Published in Cardiovascular diabetology (02-07-2021)“…Myocardial fibrosis is a multistep process, which results in collagen deposition in the injured muscle. Empagliflozin, a sodium-glucose cotransporter 2…”
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The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications
Published in Journal of diabetes research (19-10-2022)“…Background. Type 2 diabetes mellitus (T2DM), especially hyperglycemia, is associated with increased glucose cell toxicity and oxidative stress that can lead to…”
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Resolving the conflicts around Par2 opposing roles in regeneration by comparing immune-mediated and toxic-induced injuries
Published in Inflammation and Regeneration (29-11-2022)“…Abstract Background Different factors may lead to hepatitis. Among which are liver inflammation and poisoning. We chose two hepatitis models, typical for these…”
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The Role of Extracellular Signal-Regulated Kinase Pathways in Different Models of Cardiac Hypertrophy in Rats
Published in Biomedicines (22-08-2023)“…Cardiac hypertrophy develops following different triggers of pressure or volume overload. In several previous studies, different hypertrophy types were…”
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High-Intensity Training Improves Global and Segmental Strains in Severe Congestive Heart Failure
Published in Journal of cardiac failure (01-05-2017)“…Abstract Background High intensity training (HIT) is superior to moderate aerobic training (MAT) for improving quality of life in congestive heart failure…”
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Localized Antileptin Therapy Prevents Aortic Root Dilatation and Preserves Left Ventricular Systolic Function in a Murine Model of Marfan Syndrome
Published in Journal of the American Heart Association (18-05-2020)“…Background Marfan syndrome (MFS) is a genetically transmitted connective tissue disorder characterized by aortic root dilatation, dissection, and rupture…”
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Layer-specific strain analysis by speckle tracking echocardiography reveals differences in left ventricular function between rats and humans
Published in American journal of physiology. Heart and circulatory physiology (01-09-2010)“…The rat heart is commonly used as an experimental model of the human heart in both health and disease states, assuming that heart function of rats and humans…”
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993 The molecular effects of SGLT2i (Empagliflozin) on α-Klotho and Nephrin/Podocin proteins in type II diabetic mice model
Published in Nephrology, dialysis, transplantation (23-05-2024)Get full text
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2601 THE MOLECULAR EFFECT OF SGLT2I ON THE AUTOPHAGY PATHWAY IN TYPE II DIABETES MELLITUS AND ITS VASCULAR COMPLICATIONS
Published in Nephrology, dialysis, transplantation (14-06-2023)Get full text
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Vasodilation and blood pressure-lowering effect mediated by 5,6-EEQ lactone in 5/6 nephrectomy hypertensive rats
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-12-2021)“…Microvascular dysfunction is a key contributor to vascular hypertension, one of the most common chronic diseases in the world. Microvascular dysfunction leads…”
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Electrospun extracellular matrix scaffold improves cardiac structure and function post‐myocardial infarction
Published in Polymers for advanced technologies (01-11-2022)“…The current unmet clinical need for post‐myocardial infarction (MI) treatments has driven the development of diverse scaffolds for regenerating the infarcted…”
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Paraoxonase 1 hydrolysis of EPA-derived lactone impairs endothelial-mediated vasodilation
Published in Prostaglandins & other lipid mediators (01-10-2022)“…Human serum paraoxonase-1 (PON1) is a lactonase that plays a significant role in anti-atherosclerotic high-density lipoprotein (HDL) activity. PON1 is also…”
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Opposite PAR2 roles in liver regeneration from autoimmune or direct damage. Solving the conflict
Published in Journal of hepatology (01-07-2022)Get full text
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Local delivery of mometasone furoate from an eluting endotracheal tube
Published in Journal of controlled release (28-02-2018)“…Laryngeal and tracheal morbidity is a common complication of endotracheal tube (ETT)-based airway management, and manifests as local irritation, inflammation,…”
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In-vitro assessment of the thrombolytic efficacy of therapeutic ultrasound
Published in Thrombosis research (01-06-2019)“…Ultrasound is mainly used as a diagnostic tool. Several studies demonstrated that therapeutic ultrasound (TUS) can enhance thrombolysis, but the optimal…”
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