Search Results - "ERNST, Pierre"

Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…The long-term natural history of chronic obstructive pulmonary disease (COPD) in terms of successive severe exacerbations and mortality is unknown. The authors…”
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Comparative Effectiveness and Safety of LABA-LAMA vs LABA-ICS Treatment of COPD in Real-World Clinical Practice by Suissa, Samy, Dell’Aniello, Sophie, Ernst, Pierre

“…Long-acting β2-agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are recommended as initial maintenance treatments for COPD, with their…”
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Inhaled corticosteroids in COPD: the clinical evidence by Ernst, Pierre, Saad, Nathalie, Suissa, Samy

“…In this article, we focus on the scientific evidence from randomised trials supporting treatment with inhaled corticosteroids (ICS) in chronic obstructive…”
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Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…Long-acting β2 agonists (LABAs) and long-acting muscarinic antagonists (LAMAs) are the recommended initial maintenance treatment for chronic obstructive…”
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Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…The cardiovascular risk of concurrently using long-acting β -agonists (LABAs) and anticholinergics (LAMAs) in COPD is uncertain. We assessed the comparative…”
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Triple Inhaler versus Dual Bronchodilator Therapy in COPD: Real-World Effectiveness on Mortality by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…Randomized trials of triple therapy including an inhaled corticosteroid (ICS) for chronic obstructive pulmonary disease (COPD) reported remarkable benefits on…”
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Inhaled Corticosteroids and the Risks of Diabetes Onset and Progression by Suissa, Samy, PhD, Kezouh, Abbas, PhD, Ernst, Pierre, MD, MSc

“…Abstract Background Systemic corticosteroids are known to increase diabetes risk, but the effects of high-dose inhaled corticosteroids are unknown. We assessed…”
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Real-World Effectiveness of Single-Inhaler Triple Therapy for COPD: Impact of Diabetes Comorbidity by Eilat-Tsanani, Sophia, Ernst, Pierre, Suissa, Samy

“…Type 2 diabetes is a frequent comorbidity in chronic obstructive pulmonary disease (COPD) patients, with the GOLD treatment recommendations asserting that the…”
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Discontinuation of Inhaled Corticosteroids in COPD and the Risk Reduction of Pneumonia by Suissa, Samy, PhD, Coulombe, Janie, MSc, Ernst, Pierre, MD

“…Background The widespread use of inhaled corticosteroids (ICSs) for COPD treatment has been questioned. Recent studies of weaning some patients with COPD off…”
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Fluticasone-Based versus Budesonide-Based Triple Therapies in COPD: Real-World Comparative Effectiveness and Safety by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…Triple therapy for chronic obstructive pulmonary disease (COPD) is recommended for some patients, but the inhaled corticosteroids (ICS) may differ in…”
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Discontinuation of Inhaled Corticosteroids from Triple Therapy in COPD: Effects on Major Outcomes in Real World Clinical Practice by Suissa, Samy, Dell'Aniello, Sophie, Ernst, Pierre

“…Recent reports provide evidence-based guidelines for the withdrawal of inhaled corticosteroids (ICS) in COPD, but data on patients treated with ICS-based…”
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Effectiveness of Aspirin on Major COPD Outcomes: A Prevalent New-User Design Observational Study by Khouri, Charles, Dell'Aniello, Sophie, Ernst, Pierre, Suissa, Samy

“…Observational studies that have reported an association between aspirin use in chronic obstructive pulmonary disease (COPD) with reductions in mortality and…”
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The INPULSIS enigma: exacerbations in idiopathic pulmonary fibrosis by Suissa, Samy, Ernst, Pierre

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Comparative Effects of LAMA-LABA-ICS vs LAMA-LABA for COPD by Suissa, Samy, Dell’Aniello, Sophie, Ernst, Pierre

“…Triple therapy combinations of a long-acting muscarinic antagonist (LAMA), a long-acting beta2-agonist (LABA), and an inhaled corticosteroid (ICS) for COPD…”
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The use of inhaled corticosteroids and the risk of adrenal insufficiency by LAPI, Francesco, KEZOUH, Abbas, SUISSA, Samy, ERNST, Pierre

“…Adrenal insufficiency is a potential complication of therapy with an inhaled corticosteroid (ICS). Although prior studies found the highest risk of adrenal…”
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Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease and the Risk of Hospitalization for Pneumonia by Ernst, Pierre, Gonzalez, Anne V, Brassard, Paul, Suissa, Samy

“…Inhaled corticosteroids are commonly prescribed to patients with chronic obstructive pulmonary disease (COPD). To examine whether these medications might be…”
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Sodium glucose cotransporter 2 inhibitors and risk of major adverse cardiovascular events: multi-database retrospective cohort study by Filion, Kristian B, Lix, Lisa M, Yu, Oriana HY, Dell’Aniello, Sophie, Douros, Antonios, Shah, Baiju R, St-Jean, Audray, Fisher, Anat, Tremblay, Eric, Bugden, Shawn C, Alessi-Severini, Silvia, Ronksley, Paul E, Hu, Nianping, Dormuth, Colin R, Ernst, Pierre, Suissa, Samy

“…AbstractObjectiveTo compare the risk of cardiovascular events between sodium glucose cotransporter 2 (SGLT2) inhibitors and dipeptidyl peptidase-4 (DPP-4)…”
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Pneumonia risk in asthma patients using inhaled corticosteroids: a quasi‐cohort study by Qian, Christina J., Coulombe, Janie, Suissa, Samy, Ernst, Pierre

“…Aim Studies have linked the use of inhaled corticosteroids (ICSs) to excess pneumonia risk in chronic obstructive pulmonary disease patients. The risk in…”
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A Multicenter Observational Study of Incretin-based Drugs and Heart Failure by Filion, Kristian B, Azoulay, Laurent, Platt, Robert W, Dahl, Matthew, Dormuth, Colin R, Clemens, Kristin K, Hu, Nianping, Paterson, J. Michael, Targownik, Laura, Turin, Tanvir C, Udell, Jacob A, Ernst, Pierre

“…In this analysis of data from several large cohorts of patients with diabetes, antidiabetic incretin-based drugs were not associated with an increased risk of…”
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Cardiovascular morbidity and mortality in COPD by Huiart, Laetitia, Ernst, Pierre, Suissa, Samy

“…COPD and cardiovascular disease (CVD) share common risk factors. We undertook to estimate rates of hospitalization and death from CVD in COPD patients relative…”
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