Search Results - "ERDOS, Benedek"
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The neuroendocrine stress response impairs hippocampal vascular function and memory in male and female rats
Published in Neurobiology of disease (15-06-2022)“…Chronic psychological stress affects brain regions involved in memory such as the hippocampus and accelerates age-related cognitive decline, including in…”
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2
Brain-derived neurotrophic factor modulates angiotensin signaling in the hypothalamus to increase blood pressure in rats
Published in American journal of physiology. Heart and circulatory physiology (15-03-2015)“…Brain-derived neurotrophic factor (BDNF) expression increases in the paraventricular nucleus of the hypothalamus (PVN) in response to hypertensive stimuli…”
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3
Nucleus of the solitary tract catecholaminergic neurons modulate the cardiovascular response to psychological stress in rats
Published in The Journal of physiology (01-10-2012)“…Key points • Exaggerated cardiovascular responses to stress increase risk for hypertension and cardiovascular disease, but the mechanisms controlling the…”
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4
Potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species
Published in Stroke (1970) (01-04-2004)“…Insulin resistance (IR) increases the risk of stroke in humans. One possible underlying factor is cerebrovascular dysfunction resulting from altered K(+)…”
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5
Novel mechanism within the paraventricular nucleus reduces both blood pressure and hypothalamic pituitary-adrenal axis responses to acute stress
Published in American journal of physiology. Heart and circulatory physiology (15-08-2015)“…Macrophage migration inhibitory factor (MIF) counteracts pressor effects of angiotensin II (ANG II) in the paraventricular nucleus of the hypothalamus (PVN) in…”
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6
Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling
Published in Pharmacology (01-01-2017)“…The aim of this study was to investigate the effect of a high salt (HS) diet on age-related changes in blood pressure (BP) and the possible role played by…”
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7
Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension
Published in Journal of hypertension (01-12-2007)“…OBJECTIVEThe present study employed a rat leptin antagonist to evaluate the role of elevated leptin in obesity-associated hypertension. METHODSFirst, leptin…”
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8
Adverse effects of reactive oxygen species on vascular reactivity in insulin resistance
Published in Antioxidants & redox signaling (01-07-2006)“…Insulin resistance (IR) has adverse effects on the reactivity of arteries and arterioles and promotes arterial hypertension and vascular occlusive diseases…”
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9
Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation
Published in Hypertension research (01-11-2009)“…We examined the effect of high-fat (HF) feeding on blood pressure (BP) regulation, including hypothalamic redox signaling, as well as the changes in diurnal…”
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10
Alterations in KATP and KCa channel function in cerebral arteries of insulin-resistant rats
Published in American journal of physiology. Heart and circulatory physiology (01-12-2002)“…We examined whether insulin resistance alters the function of ATP-dependent and Ca(2+)-activated K(+) channels (K(ATP) and K(Ca) channels, respectively) in…”
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11
BDNF shifts excitatory-inhibitory balance in the paraventricular nucleus of the hypothalamus to elevate blood pressure
Published in Journal of neurophysiology (01-10-2021)“…Presympathetic neurons in the paraventricular nucleus of the hypothalamus (PVN) play a key role in cardiovascular regulation. We have previously shown that…”
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12
Effect of age on angiotensin II-mediated downregulation of adrenomedullary catecholamine biosynthetic enzymes
Published in Experimental gerontology (01-08-2008)“…Expression of catecholamine biosynthesizing enzymes, tyrosine hydroxylase (TH) and dopamine beta hydroxylase (DβH) increase with age in the adrenal medulla,…”
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13
Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C
Published in Diabetes (New York, N.Y.) (01-05-2004)“…Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C Benedek Erdös 1 2 , James A. Snipes 1 , Allison W. Miller…”
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14
Hippocampal Vascular Dysfunction and Impaired Memory in a Neuroendocrine Model of Stress and Hypertension
Published in The FASEB journal (01-05-2021)“…The hippocampus is a deep brain structure critically involved in learning and memory that is highly susceptible to hypoxic/ischemic injury. Hypertension and…”
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15
BDNF‐Induced Changes in Synaptic Function within the Paraventricular Nucleus of the Hypothalamus (PVN) Increase Blood Pressure
Published in The FASEB journal (01-05-2021)“…Activation of PVN neurons projecting to the rostral ventrolateral medulla and spinal cord increases sympathetic activity and blood pressure (BP). Elevated…”
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16
Somatosensory pain does not affect total cerebral blood volume
Published in Neuroreport (07-05-2007)“…The effect of somatosensory pain on the total cerebral blood volume was investigated in anesthetized rats. Our results show for the first time that total…”
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17
Activation of mTOR signaling in the paraventricular nucleus of the hypothalamus (PVN) contributes to stress- and BDNF-induced hypertensive responses
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only The paraventricular nucleus of the hypothalamus (PVN) integrates afferent inputs from limbic, medullary and hypothalamic regions to orchestrate…”
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18
BDNF shifts excitatory‐inhibitory balance in the paraventricular nucleus of the hypothalamus (PVN) to elevate blood pressure
Published in The FASEB journal (01-04-2019)“…The PVN is an important cardiovascular and autonomic center involved in sympathetic nerve activity and blood pressure (BP) regulation. Stimulation of PVN…”
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19
Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-12-2004)“…Insulin-resistance (IR) impairs agonist-induced relaxation in cerebral arteries, but little is known about its effect on constrictor mechanisms. We examined…”
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20
BDNF Augments NMDA‐signaling and Reduces GABAA‐signaling in the Paraventricular Nucleus of the Hypothalamus (PVN) to Elevate Blood Pressure
Published in The FASEB journal (01-04-2020)“…Abstract only PVN presympathetic neurons, projecting to the rostral ventrolateral medulla (RVLM) or the spinal cord, play a critical role in the regulation of…”
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