Search Results - "EPSTEIN, David H"
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1
Improving translation of animal models of addiction and relapse by reverse translation
Published in Nature reviews. Neuroscience (01-11-2020)“…Critical features of human addiction are increasingly being incorporated into complementary animal models, including escalation of drug intake, punished drug…”
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2
Volitional social interaction prevents drug addiction in rat models
Published in Nature neuroscience (01-11-2018)“…Addiction treatment has not been appreciably improved by neuroscientific research. One problem is that mechanistic studies using rodent models do not…”
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3
Overdose mortality rates for opioids and stimulant drugs are substantially higher in men than in women: state-level analysis
Published in Neuropsychopharmacology (New York, N.Y.) (01-10-2023)“…Drug overdoses from opioids and stimulants are a major cause of mortality in the United States. It is unclear if there are stable sex differences in overdose…”
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4
Compulsive addiction-like aggressive behavior in mice
Published in Biological psychiatry (1969) (15-08-2017)“…Abstract Background Some people are highly motivated to seek aggressive encounters, and among those who have been incarcerated for such behavior, recidivism…”
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5
A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and Relapse
Published in Science (American Association for the Advancement of Science) (13-04-2012)“…Drug use and relapse involve learned associations between drug-associated environmental cues and drug effects. Extinction procedures in the clinic can suppress…”
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6
Incubation of Cue-Induced Cigarette Craving During Abstinence in Human Smokers
Published in Biological psychiatry (1969) (01-04-2011)“…Background Abstinent drug users remain at risk for relapse long after withdrawal subsides. Animal studies indicate that responses to drug-related cues not only…”
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7
Searching for a Signal: Self-Reported Kratom Dose-Effect Relationships Among a Sample of US Adults With Regular Kratom Use Histories
Published in Frontiers in pharmacology (01-03-2022)“…There is limited understanding regarding kratom use among US adults. Although motivations for use are increasingly understood, typical kratom doses, threshold…”
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Kratom Use in the US: Both a Regional Phenomenon and a White Middle-Class Phenomenon? Evidence From NSDUH 2019 and an Online Convenience Sample
Published in Frontiers in pharmacology (20-12-2021)“…Kratom products available in the United States are becoming increasingly diverse both in terms of content and in terms of how they are marketed. Prior survey…”
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9
Using Machine Learning to Predict Treatment Adherence in Patients on Medication for Opioid Use Disorder
Published in Journal of addiction medicine (01-01-2023)“…Patients receiving medication for opioid use disorder (MOUD) may continue using nonprescribed drugs or have trouble with medication adherence, and it is…”
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10
Nonfatal opioid overdoses before and after Covid-19: Regional variation in rates of change
Published in PloS one (09-03-2022)“…The Covid-19 pandemic and its accompanying public-health orders (PHOs) have led to (potentially countervailing) changes in various risk factors for overdose…”
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11
Real-time tracking of neighborhood surroundings and mood in urban drug misusers: Application of a new method to study behavior in its geographical context
Published in Drug and alcohol dependence (01-01-2014)“…Abstract Background Maladaptive behaviors may be more fully understood and efficiently prevented by ambulatory tools that assess people's ongoing experience in…”
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12
Examining the paradoxical effects of kratom: a narrative inquiry
Published in Frontiers in pharmacology (05-05-2023)“…Surveys and case reports have documented kratom use in the United States (US) for over a decade. However, those reports have generally not examined in depth…”
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13
Tailored, Interactive Text Messages for Enhancing Weight Loss Among African American Adults: The TRIMM Randomized Controlled Trial
Published in The American journal of medicine (01-08-2015)“…Abstract Background Helping patients control obesity remains a clinical challenge for internists, and African Americans experience obesity rates higher than…”
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14
Growing pains with kratom: experiences discussed in subreddits contrast with satisfaction expressed in surveys
Published in Frontiers in pharmacology (2024)“…"Kratom" refers to an array of bioactive products derived from , a tree indigenous to Southeast Asia. Most kratom consumers report analgesic and stimulatory…”
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15
Effect of the CRF1-receptor antagonist pexacerfont on stress-induced eating and food craving
Published in Psychopharmacology (01-12-2016)“…Rationale In rodents, antagonism of receptors for corticotropin-releasing factor (CRF) blocks stress-induced reinstatement of drug or palatable food seeking…”
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16
Tobacco, cocaine, and heroin: Craving and use during daily life
Published in Addictive behaviors (01-04-2010)“…Abstract Background Relationships among tobacco smoking, tobacco craving, and other drug use and craving may have treatment implications in polydrug-dependent…”
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17
Cheesecake-eating rats and the question of food addiction
Published in Nature neuroscience (01-05-2010)“…Rats given extended access to high-fat high-sugar food show behavioral and physiological changes that are similar to those caused by drugs of abuse. However,…”
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Health Outcomes by Neighborhood (HON): Effects of Neighborhood, Social Instability, and Health Factors on 12-Month Trajectories of Substance-Use Disorder Symptoms
Published in Substance use & misuse (2023)“…Previous studies have shown that environment and health can influence drug use trajectories and the effects of substance use disorder (SUD) treatments. We…”
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Prediction of stress and drug craving ninety minutes in the future with passively collected GPS data
Published in NPJ digital medicine (04-03-2020)“…Just-in-time adaptive interventions (JITAIs), typically smartphone apps, learn to deliver therapeutic content when users need it. The challenge is to “push”…”
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For Better or Worse: Self-reported Changes in Kratom and Other Substance Use as a Result of the COVID-19 Pandemic
Published in Substance abuse : research and treatment (01-09-2022)“…Background: Kratom is taken to self-treat pain and symptoms of psychiatric disorders, including substance-use disorders (SUDs) and opioid withdrawal. Before…”
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