Search Results - "EPPOLITO, C"

A prime/boost vaccine platform efficiently identifies CD27 agonism and depletion of myeloid-derived suppressor cells as therapies that rationally combine with checkpoint blockade in ovarian cancer by McGray, A. J. R., Eppolito, C., Miliotto, A., Singel, K. L., Stephenson, K., Lugade, A., Segal, B. H., Keler, T., Webster, G., Lichty, B., Kozbor, D., Odunsi, K.

“…Cancer immunotherapies have generated remarkable clinical responses for some patients with advanced/metastatic disease, prompting exploration of rational…”
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IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21 by Moroz, Adrianna, Eppolito, Cheryl, Li, Qingsheng, Tao, Jianming, Clegg, Christopher H, Shrikant, Protul A

“…Cytokines that use the common receptor gamma-chain for regulating CD8(+) T cell responses to Ag include IL-2, IL-15, and the recently identified IL-21. The…”
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Murine splenic macrophage tumoricidal activation by cytokines by Verstovsek, S, Eppolito, C, Ujhazy, P, Maccubbin, D L, Ehrke, M J, Mihich, E

“…Interleukin-2 (IL-2), IL-1 beta, interferon-gamma (IFN-gamma), and tumor necrosis factor-alpha (TNF-alpha), each alone and in all possible combinations, were…”
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Aspergillus fumigatus extract differentially regulates antigen-specific CD4+ and CD8+ T cell responses to promote host immunity by Tao, Jianming, Segal, Brahm H., Eppolito, Cheryl, Li, Qingsheng, Dennis, Carly G., Youn, Richard, Shrikant, Protul A.

“…Invasive aspergillosis is a major cause of morbidity and mortality in the severely immunocompromised. The paucity of information about the mechanisms by which…”
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The acute phase protein haptoglobin regulates host immunity by Huntoon, Kristin M., Wang, Yanping, Eppolito, Cheryl A., Barbour, Karen W., Berger, Franklin G., Shrikant, Protul A., Baumann, Heinz

“…The contribution of acute phase plasma proteins to host immune responses remains poorly characterized. To better understand the role of the acute phase…”
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TNF-alpha potentiation of the lymphokine-activated killer response of murine thymus cells by Ujházy, P, Maccubbin, D, Eppolito, C, Mihich, E, Ehrke, M J

“…The role of tumor necrosis factor (TNF-alpha) on in vitro generation of lymphokine-activated killer (LAK) cells from murine thymocytes was investigated and…”
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Inhibition by selected anticancer agents of the development of primary cell-mediated immunity against allogeneic tumor cells in culture by Orsini, F, Eppolito, C, Ehrke, M J, Mihich, E

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Identification, characterization, and cloning of TIP-B1, a novel protein inhibitor of tumor necrosis factor-induced lysis by BERLETH, E. S, NADADUR, S, HENN, A. D, EPPOLITO, C, SHIOJIRI, S, GURTOO, H. L, EHRKE, M. J, MIHICH, E

“…Some cancer cells evade elimination by virtue of their insensitivity to agents that induce apoptosis. Conversely, the side effects of anticancer agents could…”
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Doxorubicin plus tumor necrosis factor α combination treatments in EL4-lymphoma-bearing C57BL/6 mice by EHRKE, M. J, VERSTOVSEK, S, UJHAZY, P, MEER, J. M, EPPOLITO, C, MACCUBBIN, D. L, MIHICH, E

“…The therapeutic efficacy of a total of 42 single-agent or combination protocols involving doxorubicin (Adriamycin, ADM) and tumor necrosis factor alpha…”
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Immunological responses critical to the therapeutic effects of adriamycin plus interleukin 2 in C57BL/6 mice bearing syngeneic EL4 lymphoma by Ho, R L, Maccubbin, D L, Ujházy, P, Zaleskis, G, Eppolito, C, Mihich, E, Ehrke, M J

“…A safe and effective therapeutic combination of moderate doses of Adriamycin (doxorubicin, 4 mg/kg, IV, Days 1 and 8 or only Day 8) plus prolonged…”
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Selective modulation by α-difluoromethylornithine of T-lymphocyte and antibody-mediated cytotoxic responses to mouse tumor allografts by EHRKE, M. J, PORTER, C. W, EPPOLITO, C, MIHICH, E

“…alpha-Difluoromethylornithine (DFMO), an inhibitor of polyamine biosynthesis, has been shown to be growth inhibitory in a wide variety of normal and tumor cell…”
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The effect of PS-K, a protein bound polysaccharide, on immune responses against allogeneic antigens by Ehrke, M J, Reino, J M, Eppolito, C, Mihich, E

“…A single dose of PS-K administered to C57B1/6J mice after immunization augmented both the humoral and cellular allogeneic responses against P815 tumor cells…”
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