Search Results - "ENOCH, M. A"

Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women by Ducci, F, Enoch, M-A, Hodgkinson, C, Xu, K, Catena, M, Robin, R W, Goldman, D

“…Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among male subjects, a…”
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Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence by Enoch, M-A, Gorodetsky, E, Hodgkinson, C, Roy, A, Goldman, D

“…The 5-HT3 receptor is rapidly potentiated by ethanol and mediates fast excitatory serotonin (5-HT) transmission that modulates dopamine release in the reward…”
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Expression of glutamatergic genes in healthy humans across 16 brain regions; altered expression in the hippocampus after chronic exposure to alcohol or cocaine by Enoch, M.‐A., Rosser, A. A., Zhou, Z., Mash, D. C., Yuan, Q., Goldman, D.

“…We analyzed global patterns of expression in genes related to glutamatergic neurotransmission (glutamatergic genes) in healthy human adult brain before…”
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The interactive effect of MAOA‐LPR genotype and childhood physical neglect on aggressive behaviors in Italian male prisoners by Gorodetsky, E., Bevilacqua, L., Carli, V., Sarchiapone, M., Roy, A., Goldman, D., Enoch, M.‐A.

“…Aggressive disorders are moderately heritable; therefore, identification of genetic influences is important. The X‐linked MAOA gene, encoding the MAOA enzyme,…”
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The influence of FKBP5 genotype on expression of FKBP5 and other glucocorticoid‐regulated genes, dependent on trauma exposure by Yeo, S., Enoch, M.‐A., Gorodetsky, E., Akhtar, L., Schuebel, K., Roy, A., Goldman, D.

“…The FK506 binding protein 51 (FKBP5), an intrinsic regulator of the glucocorticoid receptor, has been associated with pathological behaviors particularly in…”
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Predictors for self‐directed aggression in Italian prisoners include externalizing behaviors, childhood trauma and the serotonin transporter gene polymorphism 5‐HTTLPR by Gorodetsky, E., Carli, V., Sarchiapone, M., Roy, A., Goldman, D., Enoch, M.‐A.

“…Suicidal behavior and self‐mutilation can be regarded as the expression of self‐directed aggression and both are common in prison populations. We investigated…”
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Early life stress, MAOA, and gene‐environment interactions predict behavioral disinhibition in children by Enoch, M.‐A., Steer, C. D., Newman, T. K., Gibson, N., Goldman, D.

“…Several, but not all, studies have shown that the monoamine oxidase A functional promoter polymorphism (MAOA‐LPR) interacts with childhood adversity to predict…”
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The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects by Ray, L. A., Sehl, M., Bujarski, S., Hutchison, K., Blaine, S., Enoch, M.‐A.

“…The corticotropin‐releasing hormone type I receptor (CRHR1) gene has been implicated in the liability for neuropsychiatric disorders, particularly under…”
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COMT Val158Met and cognition: main effects and interaction with educational attainment by Enoch, M.‐A., Waheed, J. F., Harris, C. R., Albaugh, B., Goldman, D.

“…Studies in children have shown that the genetic influence on cognition is positively correlated with socioeconomic status. Catechol‐O‐methyltransferase (COMT)…”
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Association of galanin haplotypes with alcoholism and anxiety in two ethnically distinct populations by BELFER, I, HIPP, H, GOLDMAN, D, ENOCH, M. A, MCKNIGHT, C, EVANS, C, BUZAS, B, BOLLETTINO, A, ALBAUGH, B, VIRKKUNEN, M, YUAN, Q, MAX, M. B

“…The neuropeptide galanin (GAL) is widely expressed in the central nervous system. Animal studies have implicated GAL in alcohol abuse and anxiety: chronic…”
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EEG phenotype in alcoholism: increased coherence in the depressive subtype by Winterer, G., Enoch, M.-A., White, K. V., Saylan, M., Coppola, R., Goldman, D.

“…Objective:  Electroencephalography (EEG) power and coherence changes may be trait markers for alcoholism providing clues to brain mechanisms of vulnerability…”
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A preliminary study suggests that nicotine and prefrontal dopamine affect cortico‐striatal areas in smokers with performance feedback by Lee, M. R., Gallen, C. L., Ross, T. J., Kurup, P., Salmeron, B. J., Hodgkinson, C. A., Goldman, D., Stein, E. A., Enoch, M. A.

“…Nicotine and tonic dopamine (DA) levels [as inferred by catechol‐O‐methyl tranferase (COMT) Val158Met genotype] interact to affect prefrontal processing…”
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Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/A by ENOCH, M.-A, GOLDMAN, D, BARNETT, R, SHER, L, MAZZANTI, C. M, ROSENTHAL, N. E

“…Genes involved in serotonin metabolism are good candidates for the pathogenesis of seasonal affective disorder (SAD). A functional variant in the serotonin…”
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Alcoholism is associated with GALR3 but not two other galanin receptor genes by Belfer, I., Hipp, H., Bollettino, A., McKnight, C., Evans, C., Virkkunen, M., Albaugh, B., Max, M. B., Goldman, D., Enoch, M. A.

“…The neuropeptide galanin is widely expressed in the periphery and the central nervous system and mediates diverse physiological processes and behaviors…”
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5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder by ENOCH, M.-A, KAYE, W. H, ROTONDO, A, GREENBERG, B. D, MURPHY, D. L, GOLDMAN, D

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The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G x E effects by RAY, L. A, SEHL, M, BUJARSKI, S, HUTCHISON, K, BLAINE, S, ENOCH, M.-A

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Genetics of alcoholism and substance abuse by Enoch, M A, Goldman, D

“…Twin studies have demonstrated that addictive disorders are genetically and environmentally influenced. Our knowledge of behavioral differences predisposing to…”
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Association of Low-Voltage Alpha EEG With a Subtype of Alcohol Use Disorders by Enoch, Mary-Anne, White, Kenneth V., Harris, Claudia R., Robin, Robert W., Ross, Jerilyn, Rohrbaugh, John W., Goldman, David

“…Background: Neurophysiological traits may identify more homogeneous subgroups of alcoholics. Such discoveries could yield information regarding…”
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Understanding behaviour in a complex environment. The sixth annual meeting of the International Behavioural and Neural Genetics Society, New Orleans, LA, USA, November 5–7, 2003 by Bouwknecht, J A., Enoch, M.‐A.

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Does a reduced sensitivity to bitter taste increase the risk of becoming nicotine addicted? by Enoch, Mary-Anne, Harris, Claudia R, Goldman, David

“…Cigarette smoking appears to be on the increase in adolescents. The initiation of regular smoking nearly always begins before adulthood. It is therefore…”
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