Search Results - "ENGELHARD, Martin"

Quest for the chemical synthesis of proteins by Engelhard, Martin

“…The chemical synthesis of proteins has been the wish of chemists since the early 19th century. There were decisive methodological steps necessary to accomplish…”
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Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease by Ulbrich, Sarah, Janning, Petra, Seidel, Ralf, Matschke, Jakob, Gonsberg, Anika, Jung, Sebastian, Glatzel, Markus, Engelhard, Martin, Winklhofer, Konstanze F, Tatzelt, Jörg

“…The cellular prion protein (PrPC) is implicated in neuroprotective signaling and neurotoxic pathways in both prion diseases and Alzheimer's disease (AD)…”
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Secondary Structure, Dynamics, and Topology of a Seven-Helix Receptor in Native Membranes, Studied by Solid-State NMR Spectroscopy by Etzkorn, Manuel, Martell, Swetlana, Andronesi, Ovidiu C., Seidel, Karsten, Engelhard, Martin, Baldus, Marc

“…In the loop: High‐resolution solid‐state NMR spectroscopy is used to study the secondary structure, dynamics, and membrane topology of an entire seven‐helix…”
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Molecular Impact of the Membrane Potential on the Regulatory Mechanism of Proton Transfer in Sensory Rhodopsin II by Jiang, Xiue, Engelhard, Martin, Ataka, Kenichi, Heberle, Joachim

“…Metabolism establishes a potential difference across the cell membrane of every living cell which drives and regulates secondary ion and solute transfer across…”
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Structural Characterization of Polyglutamine Fibrils by Solid-State NMR Spectroscopy by Schneider, Robert, Schumacher, Miria C., Mueller, Henrik, Nand, Deepak, Klaukien, Volker, Heise, Henrike, Riedel, Dietmar, Wolf, Gerhard, Behrmann, Elmar, Raunser, Stefan, Seidel, Ralf, Engelhard, Martin, Baldus, Marc

“…Protein aggregation via polyglutamine stretches occurs in a number of severe neurodegenerative diseases such as Huntington's disease. We have investigated…”
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Photostability of 4,4′-Dihydroxythioindigo, a Mimetic of Indigo by Dittmann, Marc, Graupner, Franziska F., Maerz, Benjamin, Oesterling, Sven, de Vivie-Riedle, Regina, Zinth, Wolfgang, Engelhard, Martin, Lüttke, Wolfgang

“…The photochemical properties of indigo, a widely used industrial dye, has attracted both experimentalists and theoreticians from the beginning. Especially the…”
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Complex Formation and Light Activation in Membrane-Embedded Sensory Rhodopsin II as Seen by Solid-State NMR Spectroscopy by Etzkorn, Manuel, Seidel, Karsten, Li, Lin, Martell, Swetlana, Geyer, Matthias, Engelhard, Martin, Baldus, Marc

“…Microbial rhodopsins execute diverse biological functions in the cellular membrane. A mechanistic understanding of their functional profile is, however, still…”
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Signaling and Adaptation Modulate the Dynamics of the Photosensoric Complex of Natronomonas pharaonis by Orekhov, Philipp S, Klose, Daniel, Mulkidjanian, Armen Y, Shaitan, Konstantin V, Engelhard, Martin, Klare, Johann P, Steinhoff, Heinz-Jürgen

“…Motile bacteria and archaea respond to chemical and physical stimuli seeking optimal conditions for survival. To this end transmembrane chemo- and…”
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Development of the signal in sensory rhodopsin and its transfer to the cognate transducer by Engelhard, Martin, Büldt, Georg, Moukhametzianov, Rouslan, Klare, Johann P, Efremov, Rouslan, Baeken, Christian, Göppner, Annika, Labahn, Jörg, Gordeliy, Valentin I

“…The microbial phototaxis receptor sensory rhodopsin II (NpSRII, also named phoborhodopsin) mediates the photophobic response of the haloarchaeon Natronomonas…”
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Active State of Sensory Rhodopsin II: Structural Determinants for Signal Transfer and Proton Pumping by Gushchin, Ivan, Reshetnyak, Anastasia, Borshchevskiy, Valentin, Ishchenko, Andrii, Round, Ekaterina, Grudinin, Sergei, Engelhard, Martin, Büldt, Georg, Gordeliy, Valentin

“…The molecular mechanism of transmembrane signal transduction is still a pertinent question in cellular biology. Generally, a receptor can transfer an external…”
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Microbial rhodopsins: scaffolds for ion pumps, channels, and sensors by Klare, Johann P, Chizhov, Igor, Engelhard, Martin

“…Microbial rhodopsins have been intensively researched for the last three decades. Since the discovery of bacteriorhodopsin, the scope of microbial rhodopsins…”
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Voltage- and pH-Dependent Changes in Vectoriality of Photocurrents Mediated by Wild-type and Mutant Proteorhodopsins upon Expression in Xenopus Oocytes by Lörinczi, Éva, Verhoefen, Mirka-Kristin, Wachtveitl, Josef, Woerner, Andreas C., Glaubitz, Clemens, Engelhard, Martin, Bamberg, Ernst, Friedrich, Thomas

“…Proteorhodopsin (PR), a light-driven proton pump from marine proteobacteria, exhibits photocycle characteristics similar to bacteriorhodopsin (BR) at neutral…”
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Deposition of bacteriorhodopsin protein in a purple membrane form on nitrocellulose membranes for enhanced photoelectric response by Kim, Young Jun, Neuzil, Pavel, Nam, Chang-Hoon, Engelhard, Martin

“…Bacteriorhodopsin protein (bR)-based systems are one of the simplest known biological energy converters. The robust chemical, thermal and electrochemical…”
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Transmembrane signal transduction in archaeal phototaxis: The sensory rhodopsin II-transducer complex studied by electron paramagnetic resonance spectroscopy by Klare, Johann P., Bordignon, Enrica, Engelhard, Martin, Steinhoff, Heinz-Jürgen

“…Archaeal photoreceptors, together with their cognate transducer proteins, mediate phototaxis by regulating cell motility through two-component signal…”
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Bioenergetics of the Archaea by SCHÄFER, G, ENGELHARD, M, MÜLLER, V

“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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First Steps of Retinal Photoisomerization in Proteorhodopsin by Lenz, Martin O., Huber, Robert, Schmidt, Bernhard, Gilch, Peter, Kalmbach, Rolf, Engelhard, Martin, Wachtveitl, Josef

“…The early steps (<1 ns) in the photocycle of the detergent solubilized proton pump proteorhodopsin are analyzed by ultrafast spectroscopic techniques. A…”
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Native chemical ligation of hydrophobic peptides in organic solvents by Dittmann, Marc, Sauermann, Jörg, Seidel, Ralf, Zimmermann, Wolfgang, Engelhard, Martin

“…The application of chemistry to hydrophobic peptides and membrane‐spanning helices is hampered by the fact that they are only poorly soluble in aqueous buffers…”
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Temperature and Halide Dependence of the Photocycle of Halorhodopsin from Natronobacterium pharaonis by Chizhov, Igor, Engelhard, Martin

“…The photocycle kinetics of halorhodopsin from Natronobacterium pharaonis (pHR 575) was analyzed at different temperatures and chloride concentrations as well…”
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The archaeal sensory rhodopsin II/transducer complex: a model for transmembrane signal transfer by Klare, Johann P, Gordeliy, Valentin I, Labahn, Jörg, Büldt, Georg, Steinhoff, Heinz-Jürgen, Engelhard, Martin

“…Archaebacterial photoreceptors mediate phototaxis by regulating cell motility through two-component signalling cascades. Homologs of this sensory pathway occur…”
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Transducer Binding Establishes Localized Interactions to Tune Sensory Rhodopsin II by Cisneros, David A., Oberbarnscheidt, Leoni, Pannier, Angela, Klare, Johann P., Helenius, Jonne, Engelhard, Martin, Oesterhelt, Filipp, Muller, Daniel J.

“…In haloarchaea, sensory rhodopsin II (SRII) mediates a photophobic response to avoid photo-oxidative damage in bright light. Upon light activation the receptor…”
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