Search Results - "ENGEL, Pablo"

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    Novel Role of 3'UTR-Embedded Alu Elements as Facilitators of Processed Pseudogene Genesis and Host Gene Capture by Viral Genomes by Farré, Domènec, Engel, Pablo, Angulo, Ana

    Published in PloS one (29-12-2016)
    “…Since the discovery of the high abundance of Alu elements in the human genome, the interest for the functional significance of these retrotransposons has been…”
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    Journal Article
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    Subversion of natural killer cell responses by a cytomegalovirus-encoded soluble CD48 decoy receptor by Martínez-Vicente, Pablo, Farré, Domènec, Sánchez, Carolina, Alcamí, Antonio, Engel, Pablo, Angulo, Ana

    Published in PLoS pathogens (04-04-2019)
    “…Throughout evolution, cytomegaloviruses (CMVs) have been capturing genes from their hosts, employing the derived proteins to evade host immune defenses. We…”
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    CD Maps-Dynamic Profiling of CD1-CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets by Kalina, Tomas, Fišer, Karel, Pérez-Andrés, Martin, Kuzílková, Daniela, Cuenca, Marta, Bartol, Sophinus J W, Blanco, Elena, Engel, Pablo, van Zelm, Menno C

    Published in Frontiers in immunology (23-10-2019)
    “…CD molecules are surface molecules expressed on cells of the immune system that play key roles in immune cell-cell communication and sensing the…”
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    SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen by Autio, Anu, Wang, Huan, Velázquez, Francisco, Newton, Gail, Parkos, Charles A, Engel, Pablo, Engelbertsen, Daniel, Lichtman, Andrew H, Luscinskas, Francis W

    Published in PloS one (2022)
    “…The SIRPα-CD47 axis plays an important role in T cell recruitment to sites of immune reaction and inflammation but its role in T cell antigen priming is…”
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    Discovery of the first PD-1 ligand encoded by a pathogen by Martínez-Vicente, Pablo, Poblador, Francesc, Leitner, Judith, Farré, Domènec, Steinberger, Peter, Engel, Pablo, Angulo, Ana

    Published in Frontiers in immunology (13-09-2022)
    “…Large double-stranded DNA viruses deploy multiple strategies to subvert host immune defenses. Some of these tactics are mediated by viral gene products…”
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    Cytomegalovirus m154 hinders CD48 cell-surface expression and promotes viral escape from host natural killer cell control by Zarama, Angela, Pérez-Carmona, Natàlia, Farré, Domènec, Tomic, Adriana, Borst, Eva Maria, Messerle, Martin, Jonjic, Stipan, Engel, Pablo, Angulo, Ana

    Published in PLoS pathogens (01-03-2014)
    “…Receptors of the signalling lymphocyte-activation molecules (SLAM) family are involved in the functional regulation of a variety of immune cells upon…”
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    Standardization of Workflow and Flow Cytometry Panels for Quantitative Expression Profiling of Surface Antigens on Blood Leukocyte Subsets: An HCDM CDMaps Initiative by Kužílková, Daniela, Puñet-Ortiz, Joan, Aui, Pei M, Fernández, Javier, Fišer, Karel, Engel, Pablo, van Zelm, Menno C, Kalina, Tomáš

    Published in Frontiers in immunology (11-02-2022)
    “…The Human Cell Differentiation Molecules (HCDM) organizes Human Leukocyte Differentiation Antigen (HLDA) workshops to test and name clusters of antibodies that…”
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    Decreased and Heterogeneous Neutralizing Antibody Responses Against RBD of SARS-CoV-2 Variants After mRNA Vaccination by Hernández-Luis, Pablo, Aguilar, Ruth, Pelegrin-Pérez, Judit, Ruiz-Olalla, Gemma, García-Basteiro, Alberto L, Tortajada, Marta, Moncunill, Gemma, Dobaño, Carlota, Angulo, Ana, Engel, Pablo

    Published in Frontiers in immunology (06-04-2022)
    “…The rapid spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerging variants raises concerns about their capacity to evade immune…”
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    Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family by Martínez-Vicente, Pablo, Farré, Domènec, Engel, Pablo, Angulo, Ana

    Published in Viruses (28-07-2020)
    “…The genesis of gene families by the capture of host genes and their subsequent duplication is a crucial process in the evolution of large DNA viruses. CD48 is…”
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    Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation by Zheng, Chaowen, Ricci, Jerec, Zhang, Qinqin, Alawieh, Ali, Yang, Xiaofeng, Nadig, Satish, He, Songqing, Engel, Pablo, Jin, Junfei, Atkinson, Carl, Tomlinson, Stephen

    Published in Frontiers in immunology (25-11-2021)
    “…The complement system has long been recognized as a potential druggable target for a variety of inflammatory conditions. Very few complement inhibitors have…”
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    Autoimmune B Cell Repertoire in a Mouse Model of Sjögren's Syndrome by Sáez Moya, Manuel, Gutiérrez-Cózar, Rebeca, Puñet-Ortiz, Joan, Rodríguez de la Concepción, María Luisa, Blanco, Julià, Carrillo, Jorge, Engel, Pablo

    Published in Frontiers in immunology (23-04-2021)
    “…In genetically prone individuals, chronic immune activation may lead to expansion of autoreactive lymphocyte clones that can induce organ damage developing…”
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    Ly9 (CD229) Antibody Targeting Depletes Marginal Zone and Germinal Center B Cells in Lymphoid Tissues and Reduces Salivary Gland Inflammation in a Mouse Model of Sjögren's Syndrome by Puñet-Ortiz, Joan, Sáez Moya, Manuel, Cuenca, Marta, Caleiras, Eduardo, Lazaro, Adriana, Engel, Pablo

    Published in Frontiers in immunology (16-11-2018)
    “…Sjögren's Syndrome (SjS) is a common chronic autoimmune disease characterized by the B cell hyperactivation, lymphocyte infiltration, and tissue damage of…”
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    Cutting Edge: MyD88 Controls Phagocyte NADPH Oxidase Function and Killing of Gram-Negative Bacteria by Laroux, F. Stephen, Romero, Xavier, Wetzler, Lee, Engel, Pablo, Terhorst, Cox

    Published in The Journal of immunology (1950) (01-11-2005)
    “…MyD88 is an adaptor protein for the TLR family of proteins that has been implicated as a critical mediator of innate immune responses to pathogen detection. In…”
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